Videos

Sorafenib Added to CLAG-M Produces High Rates of Complete Remission With MRD Negativity in AML and Myeloid Neoplasms

12/14/2022

Anna Halpern, MD, presents study findings showing the addition of sorafenib to cladribine, high-dose cytarabine, G-CSF, and mitoxantrone (CLAG-M) produces high rates of complete remission with MRD negativity in newly diagnosed acute myeloid leukemia (AML) and high-grade myeloid neoplasms.

This phase 1/2 trial was presented at the 2022 American Society of Hematology (ASH) Annual Meeting & Exposition in New Orleans, LA.

Source:

Halpern AB, Rodriguez-Arboli EP, Othus M, et al. Addition of Sorafenib to Cladribine, High-Dose Cytarabine, G-CSF, and Mitoxantrone (CLAG-M) in Adults with Newly-Diagnosed Acute Myeloid Leukemia (AML) and High-Grade Myeloid Neoplasms Independent of FLT3-Mutation Status: Final Results of a Phase 1/2 Study. Presented at the ASH Annual Meeting & Exposition; December 10-13, 2022; New Orleans, LA, and virtual. Abstract 4057.

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