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Waldenström Macroglobulinemia Specialty Channel

News
04/01/2024

Jordan Kadish

Jordan Kadish
Cyclophosphamide and rituximab with bortezomib demonstrated high efficacy and tolerability among patients with treatment-naive Waldenström macroglobulinemia, according to a phase 2 trial.
Cyclophosphamide and rituximab with bortezomib demonstrated high efficacy and tolerability among patients with treatment-naive Waldenström macroglobulinemia, according to a phase 2 trial.
Cyclophosphamide and rituximab...
04/01/2024
Oncology
News
02/14/2024

Amber Denham

Amber Denham
Sequential treatment escalation may improve the survival of patients with Waldenström macroglobulinemia, according to results from a recent study.
Sequential treatment escalation may improve the survival of patients with Waldenström macroglobulinemia, according to results from a recent study.
Sequential treatment escalation...
02/14/2024
Oncology
Quiz
02/02/2024
True or False: Findings from a final analysis of the phase 3 ASPEN trial indicated that zanubrutinib exhibited similar efficacy and improved safety and tolerability compared to ibrutinib among patients with Waldenström macroglobulinemia,...
True or False: Findings from a final analysis of the phase 3 ASPEN trial indicated that zanubrutinib exhibited similar efficacy and improved safety and tolerability compared to ibrutinib among patients with Waldenström macroglobulinemia,...
True or False: Findings from a...
02/02/2024
Oncology
Quiz
05/30/2023
According to findings from a trial assessing the use of bortezomib-dexamethasone, rituximab, and cyclophosphamide (B-DRC) as a first-line combination treatment for Waldenström macroglobulinemia, the median time to first response was ___ in...
According to findings from a trial assessing the use of bortezomib-dexamethasone, rituximab, and cyclophosphamide (B-DRC) as a first-line combination treatment for Waldenström macroglobulinemia, the median time to first response was ___ in...
According to findings from a...
05/30/2023
Oncology
News
04/19/2023

Jordan Kadish

Jordan Kadish
According to a recent trial, the use of bortezomib-dexamethasone, rituximab, and cyclophosphamide as a first-line combination treatment was safe and increased response rates among patients with Waldenström macroglobulinemia.
According to a recent trial, the use of bortezomib-dexamethasone, rituximab, and cyclophosphamide as a first-line combination treatment was safe and increased response rates among patients with Waldenström macroglobulinemia.
According to a recent trial, the...
04/19/2023
Oncology
Quiz
03/21/2023
True or False: According to findings of the phase 3 ASPEN trial, zanubrutinib yielded higher complete response rates and advantages in long-term safety versus ibrutinib among patients with Waldenström macroglobulinemia.
True or False: According to findings of the phase 3 ASPEN trial, zanubrutinib yielded higher complete response rates and advantages in long-term safety versus ibrutinib among patients with Waldenström macroglobulinemia.
True or False: According to...
03/21/2023
Oncology
News
06/26/2022
Study findings suggest venetoclax is safe and effective in previously treated patients with WM, including those previously exposed to BTK inhibitors.
Study findings suggest venetoclax is safe and effective in previously treated patients with WM, including those previously exposed to BTK inhibitors.
Study findings suggest...
06/26/2022
Oncology
News
05/13/2022

John Otrompke

John Otrompke
Ibrutinib added to rituximab significantly reduces risk of disease progression or death over rituximab alone for patients with Waldenström macroglobulinemia.
Ibrutinib added to rituximab significantly reduces risk of disease progression or death over rituximab alone for patients with Waldenström macroglobulinemia.
Ibrutinib added to rituximab...
05/13/2022
Oncology
News
04/07/2022

John Otrompke

John Otrompke
According to a pooled analysis of data, zanubrutinib monotherapy for patients with B-cell malignancies is consistent with the toxicity profile of BTK inhibitors.
According to a pooled analysis of data, zanubrutinib monotherapy for patients with B-cell malignancies is consistent with the toxicity profile of BTK inhibitors.
According to a pooled analysis...
04/07/2022
Oncology
Computer
Quiz
04/05/2022
True or false: A phase 2 trial found that ibrutinib monotherapy induces high rates of durable responses in patients with WM.
True or false: A phase 2 trial found that ibrutinib monotherapy induces high rates of durable responses in patients with WM.
True or false: A phase 2 trial...
04/05/2022
Oncology

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News

News
04/01/2024

Jordan Kadish

Jordan Kadish
Cyclophosphamide and rituximab with bortezomib demonstrated high efficacy and tolerability among patients with treatment-naive Waldenström macroglobulinemia, according to a phase 2 trial.
Cyclophosphamide and rituximab with bortezomib demonstrated high efficacy and tolerability among patients with treatment-naive Waldenström macroglobulinemia, according to a phase 2 trial.
Cyclophosphamide and rituximab...
04/01/2024
Oncology
News
02/14/2024

Amber Denham

Amber Denham
Sequential treatment escalation may improve the survival of patients with Waldenström macroglobulinemia, according to results from a recent study.
Sequential treatment escalation may improve the survival of patients with Waldenström macroglobulinemia, according to results from a recent study.
Sequential treatment escalation...
02/14/2024
Oncology
News
04/19/2023

Jordan Kadish

Jordan Kadish
According to a recent trial, the use of bortezomib-dexamethasone, rituximab, and cyclophosphamide as a first-line combination treatment was safe and increased response rates among patients with Waldenström macroglobulinemia.
According to a recent trial, the use of bortezomib-dexamethasone, rituximab, and cyclophosphamide as a first-line combination treatment was safe and increased response rates among patients with Waldenström macroglobulinemia.
According to a recent trial, the...
04/19/2023
Oncology
News
06/26/2022
Study findings suggest venetoclax is safe and effective in previously treated patients with WM, including those previously exposed to BTK inhibitors.
Study findings suggest venetoclax is safe and effective in previously treated patients with WM, including those previously exposed to BTK inhibitors.
Study findings suggest...
06/26/2022
Oncology
News
05/13/2022

John Otrompke

John Otrompke
Ibrutinib added to rituximab significantly reduces risk of disease progression or death over rituximab alone for patients with Waldenström macroglobulinemia.
Ibrutinib added to rituximab significantly reduces risk of disease progression or death over rituximab alone for patients with Waldenström macroglobulinemia.
Ibrutinib added to rituximab...
05/13/2022
Oncology
News
04/07/2022

John Otrompke

John Otrompke
According to a pooled analysis of data, zanubrutinib monotherapy for patients with B-cell malignancies is consistent with the toxicity profile of BTK inhibitors.
According to a pooled analysis of data, zanubrutinib monotherapy for patients with B-cell malignancies is consistent with the toxicity profile of BTK inhibitors.
According to a pooled analysis...
04/07/2022
Oncology
News
03/30/2022

John Otrompke

John Otrompke
Treatment of patients with R/R WM with the oral proteasome inhibitor ixazomib combined with subcutaneous rituximab was associated with a median duration of response of 36 months.
Treatment of patients with R/R WM with the oral proteasome inhibitor ixazomib combined with subcutaneous rituximab was associated with a median duration of response of 36 months.
Treatment of patients with R/R...
03/30/2022
Oncology
News
03/21/2022

John Otrompke

John Otrompke
Ibrutinib is a standard-of-care first line therapy for patients with WM. However, long-term follow-up results from a phase 2 trial found that for patients with WM treated with ibrutinib monotherapy, none experienced a complete response.
Ibrutinib is a standard-of-care first line therapy for patients with WM. However, long-term follow-up results from a phase 2 trial found that for patients with WM treated with ibrutinib monotherapy, none experienced a complete response.
Ibrutinib is a standard-of-care...
03/21/2022
Oncology
News
03/08/2022

John Otrompke

John Otrompke
MYD88 mutation and increased IgM peak levels help to distinguish WM from other indolent B-cell malignancies. In the study, the MYD88 mutation was found in almost all WM cases.
MYD88 mutation and increased IgM peak levels help to distinguish WM from other indolent B-cell malignancies. In the study, the MYD88 mutation was found in almost all WM cases.
MYD88 mutation and increased IgM...
03/08/2022
Oncology
News
03/01/2022
Almost half of post-relapse WM patients relapse again following auto-HCT, according to findings from a recent study.
Almost half of post-relapse WM patients relapse again following auto-HCT, according to findings from a recent study.
Almost half of post-relapse WM...
03/01/2022
Oncology

Interactive Features

Quiz
02/02/2024
True or False: Findings from a final analysis of the phase 3 ASPEN trial indicated that zanubrutinib exhibited similar efficacy and improved safety and tolerability compared to ibrutinib among patients with Waldenström macroglobulinemia,...
True or False: Findings from a final analysis of the phase 3 ASPEN trial indicated that zanubrutinib exhibited similar efficacy and improved safety and tolerability compared to ibrutinib among patients with Waldenström macroglobulinemia,...
True or False: Findings from a...
02/02/2024
Oncology
Quiz
05/30/2023
According to findings from a trial assessing the use of bortezomib-dexamethasone, rituximab, and cyclophosphamide (B-DRC) as a first-line combination treatment for Waldenström macroglobulinemia, the median time to first response was ___ in...
According to findings from a trial assessing the use of bortezomib-dexamethasone, rituximab, and cyclophosphamide (B-DRC) as a first-line combination treatment for Waldenström macroglobulinemia, the median time to first response was ___ in...
According to findings from a...
05/30/2023
Oncology
Quiz
03/21/2023
True or False: According to findings of the phase 3 ASPEN trial, zanubrutinib yielded higher complete response rates and advantages in long-term safety versus ibrutinib among patients with Waldenström macroglobulinemia.
True or False: According to findings of the phase 3 ASPEN trial, zanubrutinib yielded higher complete response rates and advantages in long-term safety versus ibrutinib among patients with Waldenström macroglobulinemia.
True or False: According to...
03/21/2023
Oncology
Computer
Quiz
04/05/2022
True or false: A phase 2 trial found that ibrutinib monotherapy induces high rates of durable responses in patients with WM.
True or false: A phase 2 trial found that ibrutinib monotherapy induces high rates of durable responses in patients with WM.
True or false: A phase 2 trial...
04/05/2022
Oncology
blood cell
Quiz
03/07/2022
True or false: The median post-relapse OS is longer in patients with WM who received ibrutinib following an auto-HCT.
True or false: The median post-relapse OS is longer in patients with WM who received ibrutinib following an auto-HCT.
True or false: The median...
03/07/2022
Oncology
blood cell
Test Your Knowledge
02/25/2022
True or false: CXCR4 mutations are associated with a lower chance of major and deep responses, as well as worse PFS, in patients with WM treated with ibrutinib therapy.
True or false: CXCR4 mutations are associated with a lower chance of major and deep responses, as well as worse PFS, in patients with WM treated with ibrutinib therapy.
True or false: CXCR4 mutations...
02/25/2022
Oncology
stethoscope
Test Your Knowledge
02/03/2022
True or false: Results of the double-blind, randomized, phase 3 iNNOVATE study confirmed the sustained efficacy of ibrutinib plus rituximab in patients with WM.
True or false: Results of the double-blind, randomized, phase 3 iNNOVATE study confirmed the sustained efficacy of ibrutinib plus rituximab in patients with WM.
True or false: Results of the...
02/03/2022
Oncology
health care
Test Your Knowledge
02/03/2022
Fill in the blank: A population-based study on patients with WM and LPL found the 5-year relative survival (RS) rate significantly ______ over time with the introduction of rituximab in the early-mid 2000s.
Fill in the blank: A population-based study on patients with WM and LPL found the 5-year relative survival (RS) rate significantly ______ over time with the introduction of rituximab in the early-mid 2000s.
Fill in the blank: A...
02/03/2022
Oncology
medical
Test Your Knowledge
01/31/2022
True or false: In contrast to prior studies, data from a real-world population-based analysis of frontline therapy found RCVP and BR had similar outcomes in patients with TN WM.
True or false: In contrast to prior studies, data from a real-world population-based analysis of frontline therapy found RCVP and BR had similar outcomes in patients with TN WM.
True or false: In contrast to...
01/31/2022
Oncology

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