Differentiated Thyroid Carcinoma Excellence Forum

Differentiated Thyroid Carcinoma

Excellence Forum

Lori Wirth, MD, Massachusetts General Hospital

Videos

Selpercatinib for Advanced RET-Driven Advanced Thyroid Cancer

03/14/2025

Lori Wirth, MD, discusses the selpercatinib for advanced RET-mutant medullary thyroid cancer and RET fusion-positive, radioactive iodine-refractory differentiated thyroid cancer.

Lori Wirth, MD, discusses the...

03/14/2025

Oncology

Neoadjuvant TKI to Downstage Unresectable DTC

Videos

Potential of Neoadjuvant Tyrosine Kinase Inhibitors to Downstage Unresectable Differentiated Thyroid Cancer

03/14/2025

Mira Milas, MD, and Christian Nasr, MD, discuss the potential of neoadjuvant tyrosine kinase inhibition to downstage unresectable differentiated thyroid cancer.

Mira Milas, MD, and Christian...

03/14/2025

Oncology

Videos

Potential of Neoadjuvant Tyrosine Kinase Inhibitors to Downstage Unresectable Differentiated Thyroid Cancer

03/14/2025

Mira Milas, MD, and Christian Nasr, MD, discuss the potential of neoadjuvant tyrosine kinase inhibition to downstage unresectable differentiated thyroid cancer.

Mira Milas, MD, and Christian...

03/14/2025

Oncology

Luz Castellanos, MD, MD Anderson Cancer Center

Videos

Omitting Adjuvant Radioactive Iodine for Select Patients With Pediatric Papillary Thyroid Carcinoma

02/27/2025

Luz Castellanos , MD;

Luz Castellanos, MD, discusses results from a study evaluating the omission of adjuvant radioactive iodine for patients with pediatric papillary thyroid carcinoma.

Luz Castellanos, MD, discusses...

02/27/2025

Oncology

Videos

The Role of BRAF V600E As Prognostic Indicator for Patients With Papillary Thyroid Carcinoma

02/27/2025

Mahsa Javid , DPhil;

Mahsa Javid, DPhil, FRCS, FRCSC, explores whether BRAF V600E mutation should still be considered a prognostic marker for patients with papillary thyroid carcinoma.

Mahsa Javid, DPhil, FRCS, FRCSC,...

02/27/2025

Oncology

Recent News

News

Modakafusp Alfa Demonstrates Antitumor Activity Among Patients With Relapsed/Refractory Multiple Myeloma

04/02/2025

Emily Estrada ;

At a tolerable and safe dose, the anti-CD38 antibody, modakafusp alfa demonstrated decreased tumor activity and immune activation among patients with relapsed/refractory multiple myeloma.

At a tolerable and safe dose,...

04/02/2025

Oncology

News

Quadruplet Therapy Demonstrates Efficacy for Treatment of Transplant-Ineligible Newly Diagnosed Multiple Myeloma

04/02/2025

Emily Estrada ;

Quadruplet therapy with isatuximab, weekly bortezomib, lenalidomide, and limited dexamethasone demonstrated safety and efficacy for older patients with transplant-ineligible MM in a phase 2 clinical trial.

Quadruplet therapy with...

04/02/2025

Oncology

News

Co-Occurrence of High-Risk Cytogenetic Abnormalities as a Predictive Marker for Multiple Myeloma

04/02/2025

Emily Estrada ;

The presence of 2 or more high-risk cytogenetic abnormalities among patients with multiple myeloma was associated with poor survival outcomes, according to a systematic review and meta-analysis.

The presence of 2 or more...

04/02/2025

Oncology

News

Pembrolizumab Plus Bevacizumab Shows Promise Among Previously Untreated Patients With Melanoma Brain Metastases

04/01/2025

Stephanie Holland ;

According to results from a phase 2 study, pembrolizumab plus bevacizumab demonstrated promise among previously untreated patients with melanoma brain metastases.

According to results from a...

04/01/2025

Oncology

News

Outcomes Without Adjuvant Radioactive Iodine Among Pediatric Patients With Papillary Thyroid Cancer

04/01/2025

Allison Casey ;

According to a retrospective cohort study, omitting adjuvant radioactive iodine therapy for pediatric patients with papillary thyroid cancer did not compromise outcomes.

According to a retrospective...

04/01/2025

Oncology

News

Lenvatinib Plus High-Dose Radioiodine Therapy Shows Promise for Patients With Metastatic Well-Differentiated Thyroid Cancer

04/01/2025

Allison Casey ;

A study found the addition of lenvatinib to high-dose radioiodine therapy showed promise in improving response for patients with metastatic well-differentiated radioiodine-avid thyroid cancer.

A study found the addition of...

04/01/2025

Oncology

News

Zenocutuzumab Demonstrates Durable Activity in NRG1 Fusion–Positive Solid Tumors

03/31/2025

Janelle Bradley ;

Findings from a phase 2 study show zenocutuzumab demonstrated durable clinical activity and a favorable safety profile in patients with NRG1 fusion–positive solid tumors, particularly non–small-cell lung and pancreatic cancers.

Findings from a phase 2 study...

03/31/2025

Oncology

FDA Approval

Durvalumab Approved for Muscle Invasive Bladder Cancer

03/31/2025

Allison Casey ;

The US FDA approved neoadjuvant durvalumab plus gemcitabine-cisplatin followed by adjuvant durvalumab after radical cystectomy for patients with muscle invasive bladder cancer.

The US FDA approved neoadjuvant...

03/31/2025

Oncology

FDA Approval

FDA Expands Approval of Lutetium Lu 177 Vipivotide Tetraxetan for Metastatic Castration-Resistant Prostate Cancer

03/28/2025

Stephanie Holland ;

Based on results from the PSMAfore trial, the FDA has expanded the approval of lutetium Lu 177 vipivotide tetraxetan to include patients with PSMA-positive metastatic castration-resistant prostate cancer previously treated with ARPIs and...

Based on results from the...

03/28/2025

Oncology

FDA Approval

FDA Approves Cabozantinib for Patients With Locally Advanced or Metastatic Well-Differentiated pNETs and epNETs

03/26/2025

Stephanie Holland ;

Based on results from the CABINET trial, the FDA has approved cabozantinib for patients 12 years of age and older with unresectable locally advanced or metastatic well-differentiated pNETs and epNETs who experienced disease progression after...

Based on results from the...

03/26/2025

Oncology