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Small-Cell Lung Cancer Specialty Channel

News
12/18/2024
Retrospective analysis results demonstrated that lurbinectedin shows promise as a potential new second-line option for patients with platinum-sensitive small cell lung cancer who experience relapse after platinum-based treatment.
Retrospective analysis results demonstrated that lurbinectedin shows promise as a potential new second-line option for patients with platinum-sensitive small cell lung cancer who experience relapse after platinum-based treatment.
Retrospective analysis results...
12/18/2024
Oncology
News
12/10/2024
According to results from a real-world analysis, chemoimmunotherapy demonstrated long-term efficacy among patients with extensive-stage small cell lung cancer.
According to results from a real-world analysis, chemoimmunotherapy demonstrated long-term efficacy among patients with extensive-stage small cell lung cancer.
According to results from a...
12/10/2024
Oncology
FDA Alerts
12/05/2024
Based on results from the ADRIATIC trial, the FDA has approved durvalumab for adult patients with limited-stage small cell lung cancer who have not experienced disease progression following concurrent platinum-based chemotherapy and...
Based on results from the ADRIATIC trial, the FDA has approved durvalumab for adult patients with limited-stage small cell lung cancer who have not experienced disease progression following concurrent platinum-based chemotherapy and...
Based on results from the...
12/05/2024
Oncology
News
12/04/2024
Phase 2 study results demonstrated the addition of talazoparib to maintenance atezolizumab improved survival outcomes for patients with SLFN11-positive extensive-stage small cell lung cancer.
Phase 2 study results demonstrated the addition of talazoparib to maintenance atezolizumab improved survival outcomes for patients with SLFN11-positive extensive-stage small cell lung cancer.
Phase 2 study results...
12/04/2024
Oncology
News
11/19/2024
Results from the phase 3 EXTENTORCH trial demonstrated that the addition of toripalimab to first-line chemotherapy significantly improved survival among patients with extensive-stage small cell lung cancer.
Results from the phase 3 EXTENTORCH trial demonstrated that the addition of toripalimab to first-line chemotherapy significantly improved survival among patients with extensive-stage small cell lung cancer.
Results from the phase 3...
11/19/2024
Oncology
News
11/14/2024
According to results from the phase 2 LC 08-01 trial, amrubicin plus irinotecan demonstrated promising efficacy and safety among chemotherapy-naïve patients with extensive-disease small cell lung cancer.
According to results from the phase 2 LC 08-01 trial, amrubicin plus irinotecan demonstrated promising efficacy and safety among chemotherapy-naïve patients with extensive-disease small cell lung cancer.
According to results from the...
11/14/2024
Oncology
News
11/04/2024
According to results from a real-world comparison study, first-line durvalumab plus platinum-doublet chemotherapy prolonged survival compared to first-line atezolizumab plus platinum-doublet chemotherapy for patients with extensive-stage...
According to results from a real-world comparison study, first-line durvalumab plus platinum-doublet chemotherapy prolonged survival compared to first-line atezolizumab plus platinum-doublet chemotherapy for patients with extensive-stage...
According to results from a...
11/04/2024
Oncology
News
10/23/2024
According to results from the phase 3 ADRIATIC trial, adjuvant durvalumab significantly extended survival compared to placebo among patients with limited-stage small cell lung cancer.
According to results from the phase 3 ADRIATIC trial, adjuvant durvalumab significantly extended survival compared to placebo among patients with limited-stage small cell lung cancer.
According to results from the...
10/23/2024
Oncology
Conference Coverage
10/09/2024
According to interim analysis results from the ongoing phase 2 IDeate-Lung01 trial, 12 mg/kg of ifinatamab deruxtecan is preferable to 8 mg/kg among patients with heavily pretreated extensive-stage small cell lung cancer.
According to interim analysis results from the ongoing phase 2 IDeate-Lung01 trial, 12 mg/kg of ifinatamab deruxtecan is preferable to 8 mg/kg among patients with heavily pretreated extensive-stage small cell lung cancer.
According to interim analysis...
10/09/2024
Oncology
Sally Lau, MD
Videos
10/08/2024
Sally Lau, MD, discusses results from the phase 1b DeLLphi-303 study which demonstrated that tarlatamab plus a PD-L1 inhibitor exhibited efficacy as a first-line maintenance therapy for patients with extensive-stage small cell lung cancer.
Sally Lau, MD, discusses results from the phase 1b DeLLphi-303 study which demonstrated that tarlatamab plus a PD-L1 inhibitor exhibited efficacy as a first-line maintenance therapy for patients with extensive-stage small cell lung cancer.
Sally Lau, MD, discusses results...
10/08/2024
Oncology
Conference Coverage
10/01/2024
According to interim analysis results from a phase 2 study, the addition of BMS-986012, a novel IgG1 monoclonal antibody, to carboplatin plus etoposide and nivolumab demonstrated promising efficacy and safety as first-line treatment for...
According to interim analysis results from a phase 2 study, the addition of BMS-986012, a novel IgG1 monoclonal antibody, to carboplatin plus etoposide and nivolumab demonstrated promising efficacy and safety as first-line treatment for...
According to interim analysis...
10/01/2024
Oncology

News

News
12/18/2024
Retrospective analysis results demonstrated that lurbinectedin shows promise as a potential new second-line option for patients with platinum-sensitive small cell lung cancer who experience relapse after platinum-based treatment.
Retrospective analysis results demonstrated that lurbinectedin shows promise as a potential new second-line option for patients with platinum-sensitive small cell lung cancer who experience relapse after platinum-based treatment.
Retrospective analysis results...
12/18/2024
Oncology
News
12/10/2024
According to results from a real-world analysis, chemoimmunotherapy demonstrated long-term efficacy among patients with extensive-stage small cell lung cancer.
According to results from a real-world analysis, chemoimmunotherapy demonstrated long-term efficacy among patients with extensive-stage small cell lung cancer.
According to results from a...
12/10/2024
Oncology
FDA Alerts
12/05/2024
Based on results from the ADRIATIC trial, the FDA has approved durvalumab for adult patients with limited-stage small cell lung cancer who have not experienced disease progression following concurrent platinum-based chemotherapy and...
Based on results from the ADRIATIC trial, the FDA has approved durvalumab for adult patients with limited-stage small cell lung cancer who have not experienced disease progression following concurrent platinum-based chemotherapy and...
Based on results from the...
12/05/2024
Oncology
News
12/04/2024
Phase 2 study results demonstrated the addition of talazoparib to maintenance atezolizumab improved survival outcomes for patients with SLFN11-positive extensive-stage small cell lung cancer.
Phase 2 study results demonstrated the addition of talazoparib to maintenance atezolizumab improved survival outcomes for patients with SLFN11-positive extensive-stage small cell lung cancer.
Phase 2 study results...
12/04/2024
Oncology
News
11/19/2024
Results from the phase 3 EXTENTORCH trial demonstrated that the addition of toripalimab to first-line chemotherapy significantly improved survival among patients with extensive-stage small cell lung cancer.
Results from the phase 3 EXTENTORCH trial demonstrated that the addition of toripalimab to first-line chemotherapy significantly improved survival among patients with extensive-stage small cell lung cancer.
Results from the phase 3...
11/19/2024
Oncology
News
11/14/2024
According to results from the phase 2 LC 08-01 trial, amrubicin plus irinotecan demonstrated promising efficacy and safety among chemotherapy-naïve patients with extensive-disease small cell lung cancer.
According to results from the phase 2 LC 08-01 trial, amrubicin plus irinotecan demonstrated promising efficacy and safety among chemotherapy-naïve patients with extensive-disease small cell lung cancer.
According to results from the...
11/14/2024
Oncology
News
11/04/2024
According to results from a real-world comparison study, first-line durvalumab plus platinum-doublet chemotherapy prolonged survival compared to first-line atezolizumab plus platinum-doublet chemotherapy for patients with extensive-stage...
According to results from a real-world comparison study, first-line durvalumab plus platinum-doublet chemotherapy prolonged survival compared to first-line atezolizumab plus platinum-doublet chemotherapy for patients with extensive-stage...
According to results from a...
11/04/2024
Oncology
News
10/23/2024
According to results from the phase 3 ADRIATIC trial, adjuvant durvalumab significantly extended survival compared to placebo among patients with limited-stage small cell lung cancer.
According to results from the phase 3 ADRIATIC trial, adjuvant durvalumab significantly extended survival compared to placebo among patients with limited-stage small cell lung cancer.
According to results from the...
10/23/2024
Oncology
Conference Coverage
10/09/2024
According to interim analysis results from the ongoing phase 2 IDeate-Lung01 trial, 12 mg/kg of ifinatamab deruxtecan is preferable to 8 mg/kg among patients with heavily pretreated extensive-stage small cell lung cancer.
According to interim analysis results from the ongoing phase 2 IDeate-Lung01 trial, 12 mg/kg of ifinatamab deruxtecan is preferable to 8 mg/kg among patients with heavily pretreated extensive-stage small cell lung cancer.
According to interim analysis...
10/09/2024
Oncology
Conference Coverage
10/01/2024
According to interim analysis results from a phase 2 study, the addition of BMS-986012, a novel IgG1 monoclonal antibody, to carboplatin plus etoposide and nivolumab demonstrated promising efficacy and safety as first-line treatment for...
According to interim analysis results from a phase 2 study, the addition of BMS-986012, a novel IgG1 monoclonal antibody, to carboplatin plus etoposide and nivolumab demonstrated promising efficacy and safety as first-line treatment for...
According to interim analysis...
10/01/2024
Oncology

Interactive Features

FDA Alerts
12/05/2024
Based on results from the ADRIATIC trial, the FDA has approved durvalumab for adult patients with limited-stage small cell lung cancer who have not experienced disease progression following concurrent platinum-based chemotherapy and...
Based on results from the ADRIATIC trial, the FDA has approved durvalumab for adult patients with limited-stage small cell lung cancer who have not experienced disease progression following concurrent platinum-based chemotherapy and...
Based on results from the...
12/05/2024
Oncology
Quiz
11/30/2022
What is the current treatment for patients with small cell lung cancer?
What is the current treatment for patients with small cell lung cancer?
What is the current treatment...
11/30/2022
Oncology
Quiz
11/09/2022
According to a retrospective study, how did the median PFS of patients with extensive stage SCLC receiving immune checkpoint inhibition and chemotherapy who had inflamed tumors compare to those patients with noninflamed tumors?
According to a retrospective study, how did the median PFS of patients with extensive stage SCLC receiving immune checkpoint inhibition and chemotherapy who had inflamed tumors compare to those patients with noninflamed tumors?
According to a retrospective...
11/09/2022
Oncology
Quiz
09/30/2022
Can PD-1 and PD-L1 inhibitors be used to treat small-cell lung cancer in addition to non-small cell lung cancer?
Can PD-1 and PD-L1 inhibitors be used to treat small-cell lung cancer in addition to non-small cell lung cancer?
Can PD-1 and PD-L1 inhibitors be...
09/30/2022
Oncology
Quiz
08/29/2022
Among patients with limited-stage SCLC, did patients in the PD-L1 positivity group of a phase 2 study published in the European Journal of Cancer experience longer PFS and OS vs patients who were PD-L1 negative when treated with durvalumab...
Among patients with limited-stage SCLC, did patients in the PD-L1 positivity group of a phase 2 study published in the European Journal of Cancer experience longer PFS and OS vs patients who were PD-L1 negative when treated with durvalumab...
Among patients with...
08/29/2022
Oncology
Quiz
07/25/2022
What treatment option in addition to platinum-based chemotherapy has become the current standard of care in the first-line setting for patients with extensive-stage small-cell lung cancer?
What treatment option in addition to platinum-based chemotherapy has become the current standard of care in the first-line setting for patients with extensive-stage small-cell lung cancer?
What treatment option in...
07/25/2022
Oncology
Quiz
07/20/2022
According to study findings, does the recently developed therapy targeting SCLC BAP1 activity iBAP-II inhibit SCLC cell viability and tumor growth in vivo?
According to study findings, does the recently developed therapy targeting SCLC BAP1 activity iBAP-II inhibit SCLC cell viability and tumor growth in vivo?
According to study findings,...
07/20/2022
Oncology
Quiz
07/14/2022
According to systemic review and meta-analysis, when does stereotactic radiosurgery not prolong overall survival compared to whole brain radiotherapy in treatment of patients with small-cell lung cancer and intracranial metastatic disease?
According to systemic review and meta-analysis, when does stereotactic radiosurgery not prolong overall survival compared to whole brain radiotherapy in treatment of patients with small-cell lung cancer and intracranial metastatic disease?
According to systemic review and...
07/14/2022
Oncology
Quiz
05/24/2022
Findings from the CAPSTONE-1 trial found that the addition of which of the following drugs to chemotherapy significantly improved overall survival in patients with extensive-stage SCLC?
Findings from the CAPSTONE-1 trial found that the addition of which of the following drugs to chemotherapy significantly improved overall survival in patients with extensive-stage SCLC?
Findings from the CAPSTONE-1...
05/24/2022
Oncology
Test Your Knowledge
02/24/2022
True or false: Discovering and targeting functional biomarkers for SCLC is crucial in understanding the molecular basis underlying tumorigenesis to better assist in improving clinical treatment.
True or false: Discovering and targeting functional biomarkers for SCLC is crucial in understanding the molecular basis underlying tumorigenesis to better assist in improving clinical treatment.
True or false: Discovering and...
02/24/2022
Oncology