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Lenvatinib Plus Pembrolizumab Did Not Significantly Improve Survival Among Patients with Metastatic Colorectal Cancer

Results From the Phase 3 LEAP-017 Trial

Featuring Akihito Kawazoe, MD


At the 2023 World Congress on Gastrointestinal Cancers, Akihito Kawazoe, MD, National Cancer Center East, Kashiwa, Japan, shared results from the phase 3 LEAP-017 trial, evaluating lenvatinib plus pembrolizumab among previously treated patients with metastatic colorectal cancer. While the lenvatainib plus pembrolizumab arm trended toward longer overall survival, progression-free survival, and objective response rate than the standard of care, the differences were not statistically significant.


Source:

Kawazoe A, Passhak M, Teng H, et al. Lenvatinib plus pembrolizumab versus standard of care for previously treated metastatic colorectal cancer (mCRC): the phase 3 LEAP-017 study. Presented at the 2023 World Congress on Gastrointestinal Cancers; June 28-July 1, 2023; Barcelona, Spain. Abstract LBA-5

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Any views and opinions expressed are those of the author(s) and/or participants and do not necessarily reflect the views, policy, or position of Oncology Learning Network or HMP Global, their employees, and affiliates.

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