onc Videos

Videos

Virgina Kaklamani, MD, MD Anderson Cancer Center, Houston, Texas

Videos

Elacestrant Efficacy Associated With Duration of Prior CDK4/6 Inhibitor Treatment

12/09/2022

At the 2022 San Antonio Breast Cancer Symposium, Virgina Kaklamani, MD, discusses the impact of the duration of CDK4/6 inhibitor treatment on the efficacy of elacestrant for patients with metastatic ER-postiive, HER2-negative breast cancer.

At the 2022 San Antonio Breast...

12/09/2022

Oncology

Mariana Chavez-MacGregor, MD, MD Anderson Cancer Center

Videos

No Improvement From Everolimus Added to Standard Endocrine Therapy for HR-Positive/HER2-Negative Breast Cancer

12/08/2022

Mariana Chavez-MacGregor, MD, shares results from the phase 3 SWOG S1207 trial, evaluating the addition of everolimus to standard endocrine therapy for patients with hormone receptor-positive, human epidermal growth factor 2-negative breast...

Mariana Chavez-MacGregor, MD,...

12/08/2022

Oncology

Leif Ellisen, MD, PhD, Mass General Cancer Center

Videos

Understanding Mechanisms of Resistance to Antibody Drug Conjugates for Breast Cancers

12/08/2022

At the 2022 San Antonio Breast Cancer Symposium, Leif Ellisen, MD, PhD, presented an educational session on mechanisms of resistance to antibody drug conjugates.

At the 2022 San Antonio Breast...

12/08/2022

Oncology

Sara Tolaney, MD, MPH, Dana-Farber Cancer Institute

Videos

How to Select Patients for Trastuzumab Deruxtecan

12/08/2022

Sara Tolaney, MD, MPH, discusses strategies for selecting patients with HER2 low breast cancer for treatment with trastuzumab deruxtecan.

Sara Tolaney, MD, MPH, discusses...

12/08/2022

Oncology

Sara Hurvitz, MD, David Geffen School of Medicine

Videos

Trastuzumab Deruxtecan Superior to T-DM1 in the Second-Line Setting for HER2-Positive Metastatic Breast Cancer

12/07/2022

Sara Hurvitz, MD, presents updated results from the phase 3 Destiny-Breast03 trial, comparing trastuzumab deruxtecan with trastuzumab emtansine in patients with HER2-positive metastatic breast cancer who progressed on first-line treatment.

Sara Hurvitz, MD, presents...

12/07/2022

Oncology

Videos

An Argument Against HER2 Low as a New Breast Cancer Subtype

12/07/2022

At the 2022 San Antonio Breast Cancer Symposium, Sara Tolaney, MD, MPH, makes the case that HER2 low should not be considered a new breast cancer subtype.

At the 2022 San Antonio Breast...

12/07/2022

Oncology

Videos

Considerations for Cardiovascular Adverse Events Associated With BTK Inhibitors for Patients With CLL

12/06/2022

Javid Moslehi, MD, discusses the cardiovascular risks associated with utilization of BTK inhibitors for patients with CLL and outlines best practices for managing these adverse events.

Javid Moslehi, MD, discusses the...

12/06/2022

Oncology

Recent News

News

Osimertinib Lacks Activity in Neoadjuvant Setting for Early-Stage Non-Small Cell Lung Cancer With EGFR Mutation

08/08/2024

Stephanie Holland ;

Results from a phase 2 study demonstrated that neoadjuvant osimertinib did not improve the major pathological response rate among patients with early-stage non-small cell lung cancer harboring an EGFR mutation.

Results from a phase 2 study...

08/08/2024

Oncology

FDA Approval

FDA Approves Denileukin Diftitox for Patients With R/R Cutaneous T-Cell Lymphoma

08/08/2024

Amber Denham ;

The US Food and Drug Administration approved novel immunotherapy denileukin diftitox-cxdl for the treatment of patients with relapsed/refractory cutaneous T-cell lymphoma after at least 1 prior systemic therapy.

The US Food and Drug...

08/08/2024

Oncology

News

Tailored Dose-Dense Chemotherapy Improved Survival Outcomes Among Patients With High-Risk Early Breast Cancer

08/07/2024

Stephanie Holland ;

According to results from the phase 3 PANTHER trial, tailored and dose-dense chemotherapy in the adjuvant setting improved survival outcomes compared to standard chemotherapy among patients with high-risk early breast cancer.

According to results from the...

08/07/2024

Oncology

News

Frontline Treatment Management for Patients With FL Reduces Risk of High-Grade Transformation to DLBCL

08/07/2024

Amber Denham ;

A recent study demonstrated that frontline treatment management reduced the risk of high-grade transformation to diffuse large B-cell lymphoma among patients with follicular lymphoma, but not among patients with marginal zone lymphoma.

A recent study demonstrated that...

08/07/2024

Oncology

News

Optimal Sotorasib Dose for Patients With KRAS G12C-Mutated Advanced Non-Small Cell Lung Cancer

08/07/2024

Stephanie Holland ;

Results from a phase 2 study found that 960 mg of sotorasib is preferable to 240 mg among patients with previously treated KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer.

Results from a phase 2 study...

08/07/2024

Oncology

FDA Approval

FDA Approves Vorasidenib for Patients With IDH1/IDH2-Mutated Grade 2 Astrocytoma or Oligodendroglioma

08/06/2024

Stephanie Holland ;

Based on results from the INDIGO trial, the FDA has approved vorasidenib for adult and pediatric patients 12 years and older with grade 2 astrocytoma or oligodendroglioma with a susceptible IDH1 or IDH2 mutation following surgery.

Based on results from the INDIGO...

08/06/2024

Oncology

FDA Approval

FDA Approves Afamitresgene Autoleucel for Certain Unresectable or Metastatic Synovial Sarcoma

08/02/2024

Allison Casey ;

On August 2, 2024, the US Food and Drug Administration (FDA) granted accelerated approval to afamitresgene autoleucel for the treatment of adult patients with certain unresectable or metastatic synovial sarcomas who had received prior...

On August 2, 2024, the US Food...

08/02/2024

Oncology

FDA Approval

FDA Approves Dostarlimab Plus Chemotherapy for Patients With Primary Advanced or Recurrent Endometrial Cancer

08/01/2024

Allison Casey ;

The FDA approved dostarlimab plus carboplatin and paclitaxel, followed by single-agent dostarlimab for patients with primary advanced or recurrent endometrial cancer.

The FDA approved dostarlimab...

08/01/2024

Oncology

News

Iadademstat and Azacitidine Combination Therapy Demonstrates Manageable Safety, Promising Efficacy for Patients With Newly Diagnosed AML

08/01/2024

Amber Denham ;

The first-line combination of iadademstat and azacitidine demonstrates a manageable safety profile and promising results among patients with acute myeloid leukemia, according to phase 2 results from the ALICE trial.

The first-line combination of...

08/01/2024

Oncology

News

Effect of Food on Selumetinib Dosing for Adolescent Patients With Neurofibromatosis Type 1 With Plexiform Neurofibromas

08/01/2024

Allison Casey ;

In the phase 1 trial, the addition of a low-fat meal with doses of selumetinib did not significantly impact selumetinib exposure or gastrointestinal toxicities among adolescent patients with neurofibromatosis type 1 with plexiform...

In the phase 1 trial, the...

08/01/2024

Oncology