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Interactive Features

Test Your Knowledge
Quiz: Can Luspatercept Reduce the Severity of MDS-Related Anemia?
02/26/2020
True or False: Luspatercept reduces the severity of anemia in patients with lower-risk MDS receiving regular red-cell transfusions.
True or False: Luspatercept reduces the severity of anemia in patients with lower-risk MDS receiving regular red-cell transfusions.
True or False: Luspatercept...
02/26/2020
Oncology
Test Your Knowledge
Quiz: Ruxolitinib Combo for Polycythemia Vera and Myelofibrosis
02/21/2020
True or false: Ruxolitinib in combination with low-dose pegylated interferon-α2 improves cell counts and reduces symptom burden in patients with polycythemia vera and myelofibrosis.
True or false: Ruxolitinib in combination with low-dose pegylated interferon-α2 improves cell counts and reduces symptom burden in patients with polycythemia vera and myelofibrosis.
True or false: Ruxolitinib in...
02/21/2020
Oncology

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Test Your Knowledge
Quiz: Does Lenalidomide Added to Azacitidine Benefit Patients With High-Risk Myeloid Malignancies?
08/05/2019
True or false: The addition of lenalidomide to azacitidine demonstrates no clinical benefit in patients with high-risk MDS, AML, and CMML.
True or false: The addition of lenalidomide to azacitidine demonstrates no clinical benefit in patients with high-risk MDS, AML, and CMML.
True or false: The addition of...
08/05/2019
Oncology
Test Your Knowledge
Quiz: Does Circulating Tumor DNA Predict Relapse of AML or MDS Post-Transplant?
04/18/2019
True or False: The noninvasive testing of serum circulating tumor DNA persistence after allogeneic stem cell transplantation could predict relapse of acute myeloid leukemia and myelodysplastic syndrome.
True or False: The noninvasive testing of serum circulating tumor DNA persistence after allogeneic stem cell transplantation could predict relapse of acute myeloid leukemia and myelodysplastic syndrome.
True or False: The noninvasive...
04/18/2019
Oncology
Test Your Knowledge
Quiz: Secondary MDS, AML in Recipients of Chemo for Solid Tumors
03/27/2019
True or False: The risk for therapy-related myelodysplastic syndrome or acute myeloid leukemia after chemotherapy is excessive and present in patients with almost all solid tumor types.
True or False: The risk for therapy-related myelodysplastic syndrome or acute myeloid leukemia after chemotherapy is excessive and present in patients with almost all solid tumor types.
True or False: The risk for...
03/27/2019
Oncology

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Interactive Case Report
Interactive Case Report: Sweet Syndrome Associated With ET Transformation to AML
10/10/2018
Read the case of a 62-year-old man diagnosed with Sweet syndrome associated with transformation to AML from ET.
Read the case of a 62-year-old man diagnosed with Sweet syndrome associated with transformation to AML from ET.
Read the case of a 62-year-old...
10/10/2018
Oncology

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Recent News

News
Osimertinib Lacks Activity in Neoadjuvant Setting for Early-Stage Non-Small Cell Lung Cancer With EGFR Mutation
08/08/2024
Results from a phase 2 study demonstrated that neoadjuvant osimertinib did not improve the major pathological response rate among patients with early-stage non-small cell lung cancer harboring an EGFR mutation.
Results from a phase 2 study demonstrated that neoadjuvant osimertinib did not improve the major pathological response rate among patients with early-stage non-small cell lung cancer harboring an EGFR mutation.
Results from a phase 2 study...
08/08/2024
Oncology
FDA Approval
FDA Approves Denileukin Diftitox for Patients With R/R Cutaneous T-Cell Lymphoma
08/08/2024
The US Food and Drug Administration approved novel immunotherapy denileukin diftitox-cxdl for the treatment of patients with relapsed/refractory cutaneous T-cell lymphoma after at least 1 prior systemic therapy.
The US Food and Drug Administration approved novel immunotherapy denileukin diftitox-cxdl for the treatment of patients with relapsed/refractory cutaneous T-cell lymphoma after at least 1 prior systemic therapy.
The US Food and Drug...
08/08/2024
Oncology
News
Tailored Dose-Dense Chemotherapy Improved Survival Outcomes Among Patients With High-Risk Early Breast Cancer
08/07/2024
According to results from the phase 3 PANTHER trial, tailored and dose-dense chemotherapy in the adjuvant setting improved survival outcomes compared to standard chemotherapy among patients with high-risk early breast cancer.
According to results from the phase 3 PANTHER trial, tailored and dose-dense chemotherapy in the adjuvant setting improved survival outcomes compared to standard chemotherapy among patients with high-risk early breast cancer.
According to results from the...
08/07/2024
Oncology
News
Frontline Treatment Management for Patients With FL Reduces Risk of High-Grade Transformation to DLBCL
08/07/2024
A recent study demonstrated that frontline treatment management reduced the risk of high-grade transformation to diffuse large B-cell lymphoma among patients with follicular lymphoma, but not among patients with marginal zone lymphoma.
A recent study demonstrated that frontline treatment management reduced the risk of high-grade transformation to diffuse large B-cell lymphoma among patients with follicular lymphoma, but not among patients with marginal zone lymphoma.
A recent study demonstrated that...
08/07/2024
Oncology
News
Optimal Sotorasib Dose for Patients With KRAS G12C-Mutated Advanced Non-Small Cell Lung Cancer
08/07/2024
Results from a phase 2 study found that 960 mg of sotorasib is preferable to 240 mg among patients with previously treated KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer.
Results from a phase 2 study found that 960 mg of sotorasib is preferable to 240 mg among patients with previously treated KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer.
Results from a phase 2 study...
08/07/2024
Oncology
FDA Approval
FDA Approves Vorasidenib for Patients With IDH1/IDH2-Mutated Grade 2 Astrocytoma or Oligodendroglioma
08/06/2024
Based on results from the INDIGO trial, the FDA has approved vorasidenib for adult and pediatric patients 12 years and older with grade 2 astrocytoma or oligodendroglioma with a susceptible IDH1 or IDH2 mutation following surgery.
Based on results from the INDIGO trial, the FDA has approved vorasidenib for adult and pediatric patients 12 years and older with grade 2 astrocytoma or oligodendroglioma with a susceptible IDH1 or IDH2 mutation following surgery.
Based on results from the INDIGO...
08/06/2024
Oncology
FDA Approval
FDA Approves Afamitresgene Autoleucel for Certain Unresectable or Metastatic Synovial Sarcoma
08/02/2024
On August 2, 2024, the US Food and Drug Administration (FDA) granted accelerated approval to afamitresgene autoleucel for the treatment of adult patients with certain unresectable or metastatic synovial sarcomas who had received prior...
On August 2, 2024, the US Food and Drug Administration (FDA) granted accelerated approval to afamitresgene autoleucel for the treatment of adult patients with certain unresectable or metastatic synovial sarcomas who had received prior...
On August 2, 2024, the US Food...
08/02/2024
Oncology
FDA Approval
FDA Approves Dostarlimab Plus Chemotherapy for Patients With Primary Advanced or Recurrent Endometrial Cancer
08/01/2024
The FDA approved dostarlimab plus carboplatin and paclitaxel, followed by single-agent dostarlimab for patients with primary advanced or recurrent endometrial cancer.
The FDA approved dostarlimab plus carboplatin and paclitaxel, followed by single-agent dostarlimab for patients with primary advanced or recurrent endometrial cancer.
The FDA approved dostarlimab...
08/01/2024
Oncology
News
Iadademstat and Azacitidine Combination Therapy Demonstrates Manageable Safety, Promising Efficacy for Patients With Newly Diagnosed AML
08/01/2024
The first-line combination of iadademstat and azacitidine demonstrates a manageable safety profile and promising results among patients with acute myeloid leukemia, according to phase 2 results from the ALICE trial.
The first-line combination of iadademstat and azacitidine demonstrates a manageable safety profile and promising results among patients with acute myeloid leukemia, according to phase 2 results from the ALICE trial.
The first-line combination of...
08/01/2024
Oncology
News
Effect of Food on Selumetinib Dosing for Adolescent Patients With Neurofibromatosis Type 1 With Plexiform Neurofibromas
08/01/2024
In the phase 1 trial, the addition of a low-fat meal with doses of selumetinib did not significantly impact selumetinib exposure or gastrointestinal toxicities among adolescent patients with neurofibromatosis type 1 with plexiform...
In the phase 1 trial, the addition of a low-fat meal with doses of selumetinib did not significantly impact selumetinib exposure or gastrointestinal toxicities among adolescent patients with neurofibromatosis type 1 with plexiform...
In the phase 1 trial, the...
08/01/2024
Oncology

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