Interactive Features

Test Your Knowledge

Quiz: Does Ropeginterferon Show Clinical Benefit for MPN?

09/27/2021

True or false: Ropeginterferon, a novel agent also used to treat polycythemia, showed clinical benefit as an effective drug with less frequent doses and less side effects in the treatment of MPN.

True or false: Ropeginterferon,...

09/27/2021

Oncology

Test Your Knowledge

Quiz: Is Fedratinib Beneficial for Patients with MF?

09/23/2021

True or false: First-line fedratinib does not improve PFS in patients with MF.

True or false: First-line...

09/23/2021

Oncology

Test Your Knowledge

Which Oral JAK2 Inhibitor Improves PFS in MF?

08/31/2021

Study findings suggest that ______, an oral JAK2 inhibitor, significantly improves PFS versus placebo as a first-line treatment in patients with MF).

Study findings suggest that...

08/31/2021

Oncology

Test Your Knowledge

Quiz: Azacitidine With or Without Venetoclax for Antecedent MDS/MPNs

06/28/2021

True or False: Venetoclax plus azacitidine led to higher rates of complete remission, a longer DoR, and median OS than azacitidine monotherapy in treatment-naïve patients with therapy-related myeloid neoplasms and antecedent MDS or MPNs.

True or False: Venetoclax plus...

06/28/2021

Oncology

Test Your Knowledge

Quiz: Patient Characteristics Tied to Outcomes in tMN or A-MDS/MPNs

06/25/2021

Patients with tMN or A-MDS/MPNs may have poor outcomes due to which of the following characteristics?

Patients with tMN or A-MDS/MPNs...

06/25/2021

Oncology

Test Your Knowledge

Quiz: Do Experts Recommend Serum PCT as Biomarker in Ph-Negative MPNs?

04/20/2021

True or false: Experts recommend the use of serum procalcitonin as a disease biomarker in patients with MPNs.

True or false: Experts recommend...

04/20/2021

Oncology

Test Your Knowledge

Quiz: Combining Azacitidine With Eprenetapopt for the Treatment of TP53-Mutant MDS

02/19/2021

True or False: The addition of azacitidine to eprenetapopt led to significantly low rates of response and remission in a study of patients with TP53-mutant MDS and oligoblastic AML.

True or False: The addition of...

02/19/2021

Oncology

Test Your Knowledge

Quiz: Is There a Link Between Serum Ferritin Level and Fibrosis in Older Patients With MF?

02/19/2021

Is there a significant link between serum ferritin level and fibrosis in older patients with MF?

Is there a significant link...

02/19/2021

Oncology

Test Your Knowledge

Quiz: HCT Tied to Extended Survival, Early Death in Patients With MF

01/28/2021

True or False: A long-term survival advantage has been demonstrated with allogeneic HCT in certain patients with MF, at the expense of possible early death.

True or False: A long-term...

01/28/2021

Oncology

Test Your Knowledge

Quiz: Which Combo Regimen Showed Promise for Advanced MPN in the PHAZAR Trial?

01/18/2021

Which combo regimen did the PHAZAR trial confirm as being well-tolerated with comparable safety for patients with advanced-phase MPN/post-MPN AML?

Which combo regimen did the...

01/18/2021

Oncology

Recent News

News

Osimertinib Lacks Activity in Neoadjuvant Setting for Early-Stage Non-Small Cell Lung Cancer With EGFR Mutation

08/08/2024

Stephanie Holland ;

Results from a phase 2 study demonstrated that neoadjuvant osimertinib did not improve the major pathological response rate among patients with early-stage non-small cell lung cancer harboring an EGFR mutation.

Results from a phase 2 study...

08/08/2024

Oncology

FDA Approval

FDA Approves Denileukin Diftitox for Patients With R/R Cutaneous T-Cell Lymphoma

08/08/2024

Amber Denham ;

The US Food and Drug Administration approved novel immunotherapy denileukin diftitox-cxdl for the treatment of patients with relapsed/refractory cutaneous T-cell lymphoma after at least 1 prior systemic therapy.

The US Food and Drug...

08/08/2024

Oncology

News

Tailored Dose-Dense Chemotherapy Improved Survival Outcomes Among Patients With High-Risk Early Breast Cancer

08/07/2024

Stephanie Holland ;

According to results from the phase 3 PANTHER trial, tailored and dose-dense chemotherapy in the adjuvant setting improved survival outcomes compared to standard chemotherapy among patients with high-risk early breast cancer.

According to results from the...

08/07/2024

Oncology

News

Frontline Treatment Management for Patients With FL Reduces Risk of High-Grade Transformation to DLBCL

08/07/2024

Amber Denham ;

A recent study demonstrated that frontline treatment management reduced the risk of high-grade transformation to diffuse large B-cell lymphoma among patients with follicular lymphoma, but not among patients with marginal zone lymphoma.

A recent study demonstrated that...

08/07/2024

Oncology

News

Optimal Sotorasib Dose for Patients With KRAS G12C-Mutated Advanced Non-Small Cell Lung Cancer

08/07/2024

Stephanie Holland ;

Results from a phase 2 study found that 960 mg of sotorasib is preferable to 240 mg among patients with previously treated KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer.

Results from a phase 2 study...

08/07/2024

Oncology

FDA Approval

FDA Approves Vorasidenib for Patients With IDH1/IDH2-Mutated Grade 2 Astrocytoma or Oligodendroglioma

08/06/2024

Stephanie Holland ;

Based on results from the INDIGO trial, the FDA has approved vorasidenib for adult and pediatric patients 12 years and older with grade 2 astrocytoma or oligodendroglioma with a susceptible IDH1 or IDH2 mutation following surgery.

Based on results from the INDIGO...

08/06/2024

Oncology

FDA Approval

FDA Approves Afamitresgene Autoleucel for Certain Unresectable or Metastatic Synovial Sarcoma

08/02/2024

Allison Casey ;

On August 2, 2024, the US Food and Drug Administration (FDA) granted accelerated approval to afamitresgene autoleucel for the treatment of adult patients with certain unresectable or metastatic synovial sarcomas who had received prior...

On August 2, 2024, the US Food...

08/02/2024

Oncology

FDA Approval

FDA Approves Dostarlimab Plus Chemotherapy for Patients With Primary Advanced or Recurrent Endometrial Cancer

08/01/2024

Allison Casey ;

The FDA approved dostarlimab plus carboplatin and paclitaxel, followed by single-agent dostarlimab for patients with primary advanced or recurrent endometrial cancer.

The FDA approved dostarlimab...

08/01/2024

Oncology

News

Iadademstat and Azacitidine Combination Therapy Demonstrates Manageable Safety, Promising Efficacy for Patients With Newly Diagnosed AML

08/01/2024

Amber Denham ;

The first-line combination of iadademstat and azacitidine demonstrates a manageable safety profile and promising results among patients with acute myeloid leukemia, according to phase 2 results from the ALICE trial.

The first-line combination of...

08/01/2024

Oncology

News

Effect of Food on Selumetinib Dosing for Adolescent Patients With Neurofibromatosis Type 1 With Plexiform Neurofibromas

08/01/2024

Allison Casey ;

In the phase 1 trial, the addition of a low-fat meal with doses of selumetinib did not significantly impact selumetinib exposure or gastrointestinal toxicities among adolescent patients with neurofibromatosis type 1 with plexiform...

In the phase 1 trial, the...

08/01/2024

Oncology