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Effect of Proton Pump Inhibitor Use on Glioblastoma Survival Outcomes


Michael Castro, MD, Beverly Hills Cancer Center, California, discusses the results of a retrospective study evaluating the effect proton pump inhibition use may have on survival outcomes of patients with glioblastoma.

In this real-world evidence dataset, the use of proton pump inhibitors appeared to antagonize chemotherapy and have a negative impact on the survival of patients with glioblastoma. 


Source:

Castro MP, Quinn J, Wasserman A, et al. Use of proton pump inhibitors (PPI) in glioblastoma (GBM) and relationship to overall survival in a national real-world evidence (RWE) database.

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