Expert Insights

Anup Kasi, MD, University of Kansas Cancer Center

Videos

Neoadjuvant Treatment Options for MSI-High Gastroesophageal Junction Cancers

04/12/2023

At the 2023 GDU GI meeting, Anup Kasi, MD, participating in a debate on treatment options for patients with microsatellite instability-high locally resectably gastric or gastroesophageal junction adenocarcinoma.

At the 2023 GDU GI meeting, Anup...

04/12/2023

Oncology

Milind Javle, MD, MD Anderson Cancer Center

Videos

The Changing Treatment Landscape of Cholangiocarcinoma

04/12/2023

At the 2023 Great Debates and Updates in GI Malignancies, Milind Javle, MD, discusses the recent developments in the treatment of patients with cholangiocarcinoma.

At the 2023 Great Debates and...

04/12/2023

Oncology

Sarah Lee, MD, NYU Langone Health, New York, NY

Videos

Effect of TMB, MSI-H, and MMR Status on Clinical Outcomes in Endometrial Cancer

04/06/2023

Sarah Lee, MD, presents data at the SGO Annual Meeting on Women’s Cancers examining the effect high tumor mutational burden, high microsatellite stability, and mismatch repair deficiency may have on clinical outcomes of patients with...

Sarah Lee, MD, presents data at...

04/06/2023

Oncology

Videos

Recent Approvals for Cholangiocarcinoma Treatment

04/06/2023

While at the 2023 Great Debates and Updates in GI Malignancies meeting in Chicago, Milind Javle, MD, reviews the latest FDA approvals in the cholangiocarcinoma space.

While at the 2023 Great Debates...

04/06/2023

Oncology

Mansoor Raza Mirza, MD, Copenhagen University Hospital, Denmark

Videos

First-Line Dostarlimab Plus Chemotherapy for Endometrial Cancer

04/06/2023

At the SGO Annual Meeting on Women’s Cancer, Mansoor Raza Mirza, MD, presents the results of the ENGOT-EN6-NSGO/GOG-3031/RUBY trial, investigating the efficacy of dostarlimab plus chemotherapy in the first line for endometrial cancer.

At the SGO Annual Meeting on...

04/06/2023

Oncology

Videos

Prognostic Value of Cutaneous Disease Severity Estimates for Chronic Graft-Versus-Host Disease

04/05/2023

Emily Baumrin, MD, shares research on the value of cutaneous disease severity estimates in predicting survival outcomes in patients with chronic GVHD.

Emily Baumrin, MD, shares...

04/05/2023

Oncology

Joyce Barlin, MD, Women’s Cancer Care Associates, Albany, NY

Videos

Chemotherapy and Radiation Sandwich Therapy vs Standard of Care for Advanced Endometrial Cancer

04/05/2023

Joyce Barlin, MD, presents data from the Lunchbox trial at the SGO Annual Meeting on Women’s Cancer, comparing chemotherapy and radiation sandwich therapy vs chemotherapy alone for patients with advanced endometrial cancer.

Joyce Barlin, MD, presents data...

04/05/2023

Oncology

Videos

High-Grade Urothelial Carcinoma With Deep Muscle Invasion

04/05/2023

Matt Galsky, MD, discusses the course of treatment he would take for a patient with high-grade urothelial carcinoma with deep muscle invasion.

Matt Galsky, MD, discusses the...

04/05/2023

Oncology

Videos

The Role of Genetics in the Management of Patients with Gastrointestinal Cancer

04/01/2023

At the 2023 Great Debates & Updates in Gastrointestinal Malignancies in Chicago, regional co-chair Sonia Kupfer, MD, discussed the significant part that genetics play when treating patients with gastrointestinal cancers.

At the 2023 Great Debates &...

04/01/2023

Oncology

Anjee Davis, MPPA, Fight Colorectal Cancer

Videos

The Importance of Patient Advocacy

04/01/2023

At the 2023 Great Debates & Updates in Gastrointestinal Malignancies in Chicago, President of Fight Colorectal Cancer, Anjee Davis, MPPA, shares the importance of patient advocacy and how clinicians can help support and empower their patients...

At the 2023 Great Debates &...

04/01/2023

Oncology

Recent News

News

Osimertinib Lacks Activity in Neoadjuvant Setting for Early-Stage Non-Small Cell Lung Cancer With EGFR Mutation

08/08/2024

Stephanie Holland ;

Results from a phase 2 study demonstrated that neoadjuvant osimertinib did not improve the major pathological response rate among patients with early-stage non-small cell lung cancer harboring an EGFR mutation.

Results from a phase 2 study...

08/08/2024

Oncology

FDA Approval

FDA Approves Denileukin Diftitox for Patients With R/R Cutaneous T-Cell Lymphoma

08/08/2024

Amber Denham ;

The US Food and Drug Administration approved novel immunotherapy denileukin diftitox-cxdl for the treatment of patients with relapsed/refractory cutaneous T-cell lymphoma after at least 1 prior systemic therapy.

The US Food and Drug...

08/08/2024

Oncology

News

Tailored Dose-Dense Chemotherapy Improved Survival Outcomes Among Patients With High-Risk Early Breast Cancer

08/07/2024

Stephanie Holland ;

According to results from the phase 3 PANTHER trial, tailored and dose-dense chemotherapy in the adjuvant setting improved survival outcomes compared to standard chemotherapy among patients with high-risk early breast cancer.

According to results from the...

08/07/2024

Oncology

News

Frontline Treatment Management for Patients With FL Reduces Risk of High-Grade Transformation to DLBCL

08/07/2024

Amber Denham ;

A recent study demonstrated that frontline treatment management reduced the risk of high-grade transformation to diffuse large B-cell lymphoma among patients with follicular lymphoma, but not among patients with marginal zone lymphoma.

A recent study demonstrated that...

08/07/2024

Oncology

News

Optimal Sotorasib Dose for Patients With KRAS G12C-Mutated Advanced Non-Small Cell Lung Cancer

08/07/2024

Stephanie Holland ;

Results from a phase 2 study found that 960 mg of sotorasib is preferable to 240 mg among patients with previously treated KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer.

Results from a phase 2 study...

08/07/2024

Oncology

FDA Approval

FDA Approves Vorasidenib for Patients With IDH1/IDH2-Mutated Grade 2 Astrocytoma or Oligodendroglioma

08/06/2024

Stephanie Holland ;

Based on results from the INDIGO trial, the FDA has approved vorasidenib for adult and pediatric patients 12 years and older with grade 2 astrocytoma or oligodendroglioma with a susceptible IDH1 or IDH2 mutation following surgery.

Based on results from the INDIGO...

08/06/2024

Oncology

FDA Approval

FDA Approves Afamitresgene Autoleucel for Certain Unresectable or Metastatic Synovial Sarcoma

08/02/2024

Allison Casey ;

On August 2, 2024, the US Food and Drug Administration (FDA) granted accelerated approval to afamitresgene autoleucel for the treatment of adult patients with certain unresectable or metastatic synovial sarcomas who had received prior...

On August 2, 2024, the US Food...

08/02/2024

Oncology

FDA Approval

FDA Approves Dostarlimab Plus Chemotherapy for Patients With Primary Advanced or Recurrent Endometrial Cancer

08/01/2024

Allison Casey ;

The FDA approved dostarlimab plus carboplatin and paclitaxel, followed by single-agent dostarlimab for patients with primary advanced or recurrent endometrial cancer.

The FDA approved dostarlimab...

08/01/2024

Oncology

News

Iadademstat and Azacitidine Combination Therapy Demonstrates Manageable Safety, Promising Efficacy for Patients With Newly Diagnosed AML

08/01/2024

Amber Denham ;

The first-line combination of iadademstat and azacitidine demonstrates a manageable safety profile and promising results among patients with acute myeloid leukemia, according to phase 2 results from the ALICE trial.

The first-line combination of...

08/01/2024

Oncology

News

Effect of Food on Selumetinib Dosing for Adolescent Patients With Neurofibromatosis Type 1 With Plexiform Neurofibromas

08/01/2024

Allison Casey ;

In the phase 1 trial, the addition of a low-fat meal with doses of selumetinib did not significantly impact selumetinib exposure or gastrointestinal toxicities among adolescent patients with neurofibromatosis type 1 with plexiform...

In the phase 1 trial, the...

08/01/2024

Oncology