Expert Insights

SPONSORED VIDEO

Case-Based Discussion on Management of Select Adverse Events | Part 1: Overview of a Treatment Option for Metastatic Triple-Negative Breast Cancer

03/12/2024

Watch this product theater to help understand the key efficacy and safety data for a treatment option in second-line and later metastatic triple-negative breast cancer (mTNBC) as well as the potential management strategies for certain adverse...

Watch this product theater to...

03/12/2024

Oncology

Jennifer Amengual, MD, Columbia University

Conference Coverage

Exploring Treatment Strategies for Elderly Patients With Aggressive Lymphoma Ineligible for CAR T-Cell Therapy

03/11/2024

Featuring Jennifer Amengual, MD

Featuring Jennifer Amengual, MD ...

At the Lymphoma, Leukemia & Myeloma Congress in New York, Jennifer Amengual, MD, discusses new approvals and treatment strategies for older patients with aggressive lymphoma who are ineligible for CAR T-cell therapy.

At the Lymphoma, Leukemia &...

03/11/2024

Lymphoma, Leukemia & Myeloma Network

Petros Grivas, MD, PhD, Fred Hutchinson Cancer Center

Podcasts

Sacituzumab Govitecan Plus Pembrolizumab in the TROPHY-U-01 Trial

03/07/2024

Featured Petros Grivas, MD, PhD

Featured Petros Grivas, MD, PhD ...

Petros Grivas, MD, PhD, shares results from the phase 2 TROPHY-U-01 study evaluating sacituzumab govetican plus pembrolizumab among patients with metastatic urothelial carcinoma following progression on platinum-chemotherapy.

Petros Grivas, MD, PhD, shares...

03/07/2024

Oncology

Considerations for Managing Patients With HER2-Positive Breast Cancer

Conference Coverage

Evaluating Chemo-Free Novel Agent Combination Therapies for Mantle Cell Lymphoma

03/01/2024

Featuring Jia Ruan, MD, PhD

At the Lymphoma, Leukemia & Myeloma Congress, Jia Ruan, MD, PhD, discusses the introduction of chemotherapy-free novel agents for the treatment of patients with mantle cell lymphoma.

At the Lymphoma, Leukemia &...

03/01/2024

Lymphoma, Leukemia & Myeloma Network

Conference Coverage

Use of BTK Inhibitors in the First-Line Mantle Cell Lymphoma Treatment Landscape

03/01/2024

Featuring Jia Ruan, MD, PhD

At the Lymphoma, Leukemia & Myeloma Congress, Jia Ruan, MD, PhD, provides insight into the use of BTK inhibitors in the frontline mantle cell lymphoma treatment space.

At the Lymphoma, Leukemia &...

03/01/2024

Lymphoma, Leukemia & Myeloma Network

Conference Coverage

Advances in Chemoimmunotherapy for Frontline Mantle Cell Lymphoma Treatment

03/01/2024

Featuring Jia Ruan, MD, PhD

At the Lymphoma, Leukemia & Myeloma Congress, Jia Ruan, MD, PhD, discusses advances in chemoimmunotherapy for the first-line treatment of patients with mantle cell lymphoma.

At the Lymphoma, Leukemia &...

03/01/2024

Lymphoma, Leukemia & Myeloma Network

Recent News

News

Osimertinib Lacks Activity in Neoadjuvant Setting for Early-Stage Non-Small Cell Lung Cancer With EGFR Mutation

08/08/2024

Stephanie Holland ;

Results from a phase 2 study demonstrated that neoadjuvant osimertinib did not improve the major pathological response rate among patients with early-stage non-small cell lung cancer harboring an EGFR mutation.

Results from a phase 2 study...

08/08/2024

Oncology

FDA Approval

FDA Approves Denileukin Diftitox for Patients With R/R Cutaneous T-Cell Lymphoma

08/08/2024

Amber Denham ;

The US Food and Drug Administration approved novel immunotherapy denileukin diftitox-cxdl for the treatment of patients with relapsed/refractory cutaneous T-cell lymphoma after at least 1 prior systemic therapy.

The US Food and Drug...

08/08/2024

Oncology

News

Tailored Dose-Dense Chemotherapy Improved Survival Outcomes Among Patients With High-Risk Early Breast Cancer

08/07/2024

Stephanie Holland ;

According to results from the phase 3 PANTHER trial, tailored and dose-dense chemotherapy in the adjuvant setting improved survival outcomes compared to standard chemotherapy among patients with high-risk early breast cancer.

According to results from the...

08/07/2024

Oncology

News

Frontline Treatment Management for Patients With FL Reduces Risk of High-Grade Transformation to DLBCL

08/07/2024

Amber Denham ;

A recent study demonstrated that frontline treatment management reduced the risk of high-grade transformation to diffuse large B-cell lymphoma among patients with follicular lymphoma, but not among patients with marginal zone lymphoma.

A recent study demonstrated that...

08/07/2024

Oncology

News

Optimal Sotorasib Dose for Patients With KRAS G12C-Mutated Advanced Non-Small Cell Lung Cancer

08/07/2024

Stephanie Holland ;

Results from a phase 2 study found that 960 mg of sotorasib is preferable to 240 mg among patients with previously treated KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer.

Results from a phase 2 study...

08/07/2024

Oncology

FDA Approval

FDA Approves Vorasidenib for Patients With IDH1/IDH2-Mutated Grade 2 Astrocytoma or Oligodendroglioma

08/06/2024

Stephanie Holland ;

Based on results from the INDIGO trial, the FDA has approved vorasidenib for adult and pediatric patients 12 years and older with grade 2 astrocytoma or oligodendroglioma with a susceptible IDH1 or IDH2 mutation following surgery.

Based on results from the INDIGO...

08/06/2024

Oncology

FDA Approval

FDA Approves Afamitresgene Autoleucel for Certain Unresectable or Metastatic Synovial Sarcoma

08/02/2024

Allison Casey ;

On August 2, 2024, the US Food and Drug Administration (FDA) granted accelerated approval to afamitresgene autoleucel for the treatment of adult patients with certain unresectable or metastatic synovial sarcomas who had received prior...

On August 2, 2024, the US Food...

08/02/2024

Oncology

FDA Approval

FDA Approves Dostarlimab Plus Chemotherapy for Patients With Primary Advanced or Recurrent Endometrial Cancer

08/01/2024

Allison Casey ;

The FDA approved dostarlimab plus carboplatin and paclitaxel, followed by single-agent dostarlimab for patients with primary advanced or recurrent endometrial cancer.

The FDA approved dostarlimab...

08/01/2024

Oncology

News

Iadademstat and Azacitidine Combination Therapy Demonstrates Manageable Safety, Promising Efficacy for Patients With Newly Diagnosed AML

08/01/2024

Amber Denham ;

The first-line combination of iadademstat and azacitidine demonstrates a manageable safety profile and promising results among patients with acute myeloid leukemia, according to phase 2 results from the ALICE trial.

The first-line combination of...

08/01/2024

Oncology

News

Effect of Food on Selumetinib Dosing for Adolescent Patients With Neurofibromatosis Type 1 With Plexiform Neurofibromas

08/01/2024

Allison Casey ;

In the phase 1 trial, the addition of a low-fat meal with doses of selumetinib did not significantly impact selumetinib exposure or gastrointestinal toxicities among adolescent patients with neurofibromatosis type 1 with plexiform...

In the phase 1 trial, the...

08/01/2024

Oncology