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Hepatocellular carcinoma: 9 years of experience in the medical oncology department at Mohammed VI University Hospital in Marrakech, Morocco
Background
Hepatocellular carcinoma (HCC) is a primary malignant tumor of the liver, which remains asymptomatic for a long time. Diagnosis is most often late and its 5-year survival rate is less than 10%. It usually develops on cirrhosis, more rarely on chronic non-cirrhotic liver disease and up to 25% of patients have no risk factors. The objective of our study was to identify the incidence, epidemiology and presentation of hepatocellular carcinoma (HCC).
Methods
We undertook a monocentric retrospective study of patients treated for HCC, 50 patients were consecutively included in the registry of the medical oncology department of the Mohammed VI University Hospital Centre in Marrakech between January 2012 and December 2020.
Results
We have identified 50 patients followed for HCC. The mean average age of our patients was 56 years (range 19-86). The sex ratio was 1.31 (29 men / 21 women). The most frequent reason for consultation was pain in the right hypochondriac region (57.1%). The etiologies are dominated by cirrhosis in 42% of cases, hepatitis B and C viruses accounting for 40% of causes. histological diagnosis was obtained in 47% of cases. In the remaining cases, it was based on morphological and biological characteristic (52. 4%). according to the Child-Pugh score 36% of cases were classified as Child-Pugh B. Palliative treatment with Sorafenib was indicated in 65% of cases. The mortality remains high in patients who received palliative or symptomatic treatment.
Conclusions
Liver cancer remains a global health challenge, and hepatocellular carcinoma (HCC) represents the most common form with almost 90%. Clinical, radiological and histological data must all be taken into consideration for better management.
Legal entity responsible for the study
The author.
Funding
Has not received any funding.
Disclosures
All authors have declared no conflicts of interest.
