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Maintenance Chemotherapy With Tegafur-Uracil vs Observation for Locally Advanced Cervical Cancer


Keiichi Fujiwara, MD, PhD, Saitama Medical University International Medical Center, discusses findings from a phase 3 trial, showing that although well-tolerated, maintenance chemotherapy using tegafur-uracil for 2 years after definitive chemoradiation therapy did not improve progression-free survival (PFS) or overall survival (OS) among patients with locally advanced cervical cancer.

Dr Fujiwara presented these results at the 2022 European Society for Medical Oncology (ESMO) Congress.


Source:

Fujiwara K, Nishio S, Yamamoto K, et al. Randomized phase III trial of maintenance chemotherapy with tegafur-uracil versus observation following concurrent chemoradiotherapy for locally advanced cervical cancer, GOTIC-002 LUFT trial. Presented at: ESMO Congress; September 9-13, 2022. Paris, France and virtual. Abstract LBA31.
 

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