VIDEOS

Amcenestrant vs Physician’s Choice of Endocrine Therapy in ER-Positive, HER2-Negative Breast Cancer
Findings From the Phase 2 AMEERA-3 Trial

09/13/2022

Sara Tolaney, MD, Dana-Faber Cancer Institute, Boston, MA, discusses results from AMEERA-3, an open-label randomized phase 2 trial that explored amcenestrant vs physician’s choice of endocrine therapy in patients with endocrine-resistant ER-positive, HER2-negative advanced breast cancer.

The trial results reveal that amcenestrant was not associated with a significant improvement in progression-free survival (PFS) vs physician’s choice of endocrine therapy in this patient population. Dr Tolaney presented these findings at the 2022 European Society for Medical Oncology (ESMO) Congress.

Source:

Tolaney SM, Chan A, Petrakova K, et al. AMEERA-3, a phase II study of amcenestrant (AMC) versus endocrine treatment of physician’s choice (TPC) in patients (pts) with endocrine-resistant ER+/HER2− advanced breast cancer (aBC). Presented at: ESMO Congress; September 9-13, 2022. Paris, France and virtual. Abstract 212MO.

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