EZH2 Test Your Knowledge

Test Your Knowledge

Quiz: How Prevalent is the EZH2 Mutation in Patients With FL?

05/03/2021

Among patients with FL, approximately what percentage are reported as having activating mutations of EZH2?

Among patients with FL,...

05/03/2021

Oncology

Test Your Knowledge

Quiz: Is Tazemetostat FDA-Approved for Treating Relapsed/Refractory FL?

03/15/2021

True or false: The FDA has approved tazemetostat for the treatment of patients with confirmed EZH2-positive relapsed/refractory FL.

True or false: The FDA has...

03/15/2021

Oncology

Test Your Knowledge

Quiz: Has Tazemetostat Shown Efficacy in Treating Patients With Relapsed/Refractory FL?

02/03/2021

True or false: Tazemetostat has demonstrated durable activity in patients with relapsed/refractory FL and mutations in EZH2.

True or false: Tazemetostat has...

02/03/2021

Oncology

Test Your Knowledge

Quiz: Tumor Growth, Metastasis, and EZH2 Expression

10/15/2020

True or False: EZH2 plays a critical role in promotion of tumor growth and metastasis, and can be regulated through multiple pathways transcriptionally, post-transcriptionally, and post-translationally.

True or False: EZH2 plays a...

10/15/2020

Oncology

Test Your Knowledge

Quiz: Tazemetostat Monotherapy for Relapsed/Refractory Malignant Mesothelioma

08/13/2020

True or False: Tazemetostat is well-tolerated and yields anti-tumor activity in patients with BAP1-deficient relapsed or refractory malignant mesothelioma.

True or False: Tazemetostat is...

08/13/2020

Oncology

Test Your Knowledge

Quiz: Which of These Agents Yielded Durable Responses in Patients With Epithelioid Sarcoma?

08/13/2020

In a large clinical study, which of the following agents yielded durable responses in patients with epithelioid sarcoma?

In a large clinical study, which...

08/13/2020

Oncology

Recent News

News

Osimertinib Lacks Activity in Neoadjuvant Setting for Early-Stage Non-Small Cell Lung Cancer With EGFR Mutation

08/08/2024

Stephanie Holland ;

Results from a phase 2 study demonstrated that neoadjuvant osimertinib did not improve the major pathological response rate among patients with early-stage non-small cell lung cancer harboring an EGFR mutation.

Results from a phase 2 study...

08/08/2024

Oncology

FDA Approval

FDA Approves Denileukin Diftitox for Patients With R/R Cutaneous T-Cell Lymphoma

08/08/2024

Amber Denham ;

The US Food and Drug Administration approved novel immunotherapy denileukin diftitox-cxdl for the treatment of patients with relapsed/refractory cutaneous T-cell lymphoma after at least 1 prior systemic therapy.

The US Food and Drug...

08/08/2024

Oncology

News

Tailored Dose-Dense Chemotherapy Improved Survival Outcomes Among Patients With High-Risk Early Breast Cancer

08/07/2024

Stephanie Holland ;

According to results from the phase 3 PANTHER trial, tailored and dose-dense chemotherapy in the adjuvant setting improved survival outcomes compared to standard chemotherapy among patients with high-risk early breast cancer.

According to results from the...

08/07/2024

Oncology

News

Frontline Treatment Management for Patients With FL Reduces Risk of High-Grade Transformation to DLBCL

08/07/2024

Amber Denham ;

A recent study demonstrated that frontline treatment management reduced the risk of high-grade transformation to diffuse large B-cell lymphoma among patients with follicular lymphoma, but not among patients with marginal zone lymphoma.

A recent study demonstrated that...

08/07/2024

Oncology

News

Optimal Sotorasib Dose for Patients With KRAS G12C-Mutated Advanced Non-Small Cell Lung Cancer

08/07/2024

Stephanie Holland ;

Results from a phase 2 study found that 960 mg of sotorasib is preferable to 240 mg among patients with previously treated KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer.

Results from a phase 2 study...

08/07/2024

Oncology

FDA Approval

FDA Approves Vorasidenib for Patients With IDH1/IDH2-Mutated Grade 2 Astrocytoma or Oligodendroglioma

08/06/2024

Stephanie Holland ;

Based on results from the INDIGO trial, the FDA has approved vorasidenib for adult and pediatric patients 12 years and older with grade 2 astrocytoma or oligodendroglioma with a susceptible IDH1 or IDH2 mutation following surgery.

Based on results from the INDIGO...

08/06/2024

Oncology

FDA Approval

FDA Approves Afamitresgene Autoleucel for Certain Unresectable or Metastatic Synovial Sarcoma

08/02/2024

Allison Casey ;

On August 2, 2024, the US Food and Drug Administration (FDA) granted accelerated approval to afamitresgene autoleucel for the treatment of adult patients with certain unresectable or metastatic synovial sarcomas who had received prior...

On August 2, 2024, the US Food...

08/02/2024

Oncology

FDA Approval

FDA Approves Dostarlimab Plus Chemotherapy for Patients With Primary Advanced or Recurrent Endometrial Cancer

08/01/2024

Allison Casey ;

The FDA approved dostarlimab plus carboplatin and paclitaxel, followed by single-agent dostarlimab for patients with primary advanced or recurrent endometrial cancer.

The FDA approved dostarlimab...

08/01/2024

Oncology

News

Iadademstat and Azacitidine Combination Therapy Demonstrates Manageable Safety, Promising Efficacy for Patients With Newly Diagnosed AML

08/01/2024

Amber Denham ;

The first-line combination of iadademstat and azacitidine demonstrates a manageable safety profile and promising results among patients with acute myeloid leukemia, according to phase 2 results from the ALICE trial.

The first-line combination of...

08/01/2024

Oncology

News

Effect of Food on Selumetinib Dosing for Adolescent Patients With Neurofibromatosis Type 1 With Plexiform Neurofibromas

08/01/2024

Allison Casey ;

In the phase 1 trial, the addition of a low-fat meal with doses of selumetinib did not significantly impact selumetinib exposure or gastrointestinal toxicities among adolescent patients with neurofibromatosis type 1 with plexiform...

In the phase 1 trial, the...

08/01/2024

Oncology