Videos

Pertuzumab Retreatment Improves OS in HER2-Positive Locally Advanced or Metastatic Breast Cancer

06/08/2023

Yutaka Yamamoto, MD, Kumamoto University Hospital, Kunamoto, Japan, discusses overall survival (OS) results from the phase 3 PRECIOUS trial that evaluated pertuzumab retreatment in patients with HER2-positive locally advanced or metastatic breast cancer.

The trial demonstrated that retreatment with pertuzumab in combination with trastuzumab and chemotherapy lead to a significant improvement in OS compared to treatment with trastuzumab and chemotherapy alone.

Dr Yamamoto presented these findings at the 2023 American Society of Clinical Oncology (ASCO) Annual Meeting.

Source:

Yamamoto Y, Iwata H, Takahashi M, et al. Pertuzumab retreatment in patients with HER2-positive locally advanced/metastatic breast cancer: Overall survival results of a phase III randomized trial (JBCRG-M05: PRECIOUS). Presented at 2023 ASCO Annual Meeting; June 2-6, 2023; Chicago, IL. Abstract 1015

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