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HER2 and PD-L1 Immunohistochemistry Expression Among Patients With Advanced Bladder Cancer
At the 2024 ASCO Genitourinary Cancers Symposium, David Aggen, MD, Memorial Sloan Kettering Cancer Center, New York, New York, shared results from a retrospective analysis describing HER2 and PD-L1 expression and HER2 genomic alterations seen among patients with advanced bladder cancer.
This study found an inverse correlation between HER2 immunohistochemistry expression and PD-L1 combined positive score. These data can provide foundation for further trials in HER2-directed therapies for advanced bladder cancer.
Source:
Aggen DH, Shah NJ, Zheng J, et al. HER2 and PD-L1 immunohistochemistry (IHC) expression, and HER2 genomic alterations: Associations and clinical outcomes for advanced bladder cancer. Presented at the 2024 ASCO Genitourinary Cancers Symposium; January 25-27, 2024; San Francisco, California. Abstract 538