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Epidemiological evolution of colorectal cancer over 10 years: Incidence, mortality and survival: Experience of the medical oncology department of Fez
Background
Colorectal cancer is one of the most common types of cancer worldwide with an increase incidence over the years. The purpose of this study was to assess trends in incidence and presentation of colorectal cancer (CRC) over a period of 10 years.
Methods
This is a retrospective study of 664 patients with colon cancer treated at the medical oncology department of Fez over a period from December 2010 to September 2020. Kaplan Meier method was used to estimate median survival.
Results
The incidence of colorectal increased from 48 cases /year in 2010 to 85 new cases /year during 2020. A total of 140 cases were recorded between 2009-2012 versus 190 cases between 2017-2020. A rejuvenation of colorectal cancer has been observed with an average age ranging from 75 years in 2010 against 65 years in 2020. The sex ratio was 1.6 in 2009 versus 1.2 in 2020. The proportion of earlier stages at diagnosis increased significantly in recent years. We observed non-significant variations in tumor localization throughout the observation period. 63% were metastatic in the ten past years versus 52%. Colorectal mortality were highest during 2010(38%) versus (16%) in 2020. The median overall survival was 23 years versus 32 years in the latest years.
Conclusions
Our study showed an increased survival and reduces mortality over the 10 past years. Considerable progress has been observed in the treatment of metastatic colorectal cancer in recent years.
Legal entity responsible for the study
The author.
Funding
Department of medical oncology.
Disclosures
All authors have declared no conflicts of interest.
