Meeting Materials

This work was sponsored by University of California, San Francisco - Fresno

This work was sponsored by University of California San Francisco

This trial was funded by Otsuka Pharmaceutical Development & Commercialization, Inc.

Psychosis is a complex syndrome that involves multiple biopsychosocial factors.

Acute intermittent porphyria (AIP) is a rare autosomal dominant disease that is caused by heterozygosity for a pathogenic variant in the gene encoding porphobilinogen deaminase, also called hydroxymethylbilane synthase.

This work was sponsored by Cingulate Therapeutics, LLC

Purpose: To evaluate the safety and efficacy of CTx-1301 in adults with ADHD in a laboratory classroom setting. This study assessed the onset and duration of effect by evaluating PERMP scores.

This work was sponsored by Boehringer Ingelheim and Click Therapeutics

The drastic escalation in the mental health crisis affects 53 million Americans, resulting in a tremendous demand for psychiatric medications. However, only 37% of treatments are successful.

This work was sponsored by Noven Pharmaceuticals, Inc.

This study was funded by Otsuka Pharmaceutical Development & Commercialization, Inc.

This work was sponsored by Otsuka Pharmaceutical Development & Commercialization Inc. (Princeton, NJ, USA) and Lundbeck LLC (Deerfield, IL, USA).

This work was sponsored by Otsuka Pharmaceutical Development & Commercialization Inc. (Princeton, NJ, USA) and Lundbeck LLC (Deerfield, IL, USA).

This work was sponsored by AbbVie

This work was sponsored by BioXcel Therapeutics

Introduction: Obligate mirror alternating hemi-prosopometamorphopsia has not heretofore been described. Such a case is presented.

This work was sponsored by Myriad Genetics, Inc.

This study was funded by Avadel Pharmaceuticals.

Clozapine is the only FDA-approved drug for treatment resistance schizophrenia (TRS) and is highly effective. However, clozapine is also the third most toxic drug in the US after oxycodone and fentanyl.

This work was sponsored by Otsuka Pharmaceutical Development & Commercialization Inc. (Princeton, NJ, USA) and H. Lundbeck A/S (Valby, Denmark).

This work was sponsored by Alkermes, Inc.

This work was sponsored by Otsuka Pharmaceutical Development & Commercialization Inc. (Princeton, NJ, USA) and Lundbeck LLC (Deerfield, IL, USA).

This work was sponsored by Axsome Therapeutics

This work was sponsored by Janssen Scientific Affairs, LLC

This work was sponsored by Axsome Therapeutics

Research and clinical attention on clozapine-induced gastrointestinal hypomotility (CIGH) tends to focus primarily on constipation. However, CIGH is known to affect all aspects of the GI tract including gastric emptying and esophageal hypomotility.

This work was sponsored by Alkermes, Inc.

This work was sponsored by Teva Branded Pharmaceutical Products R&D, Inc.

This work was supported by funding from Sumitomo Pharma America (formerly Sunovion Pharmaceuticals Inc)

This study was sponsored by Otsuka Pharmaceutical Development & Commercialization Inc., Princeton, NJ, USA, and H. Lundbeck LLC, Deerfield, IL, USA.

This study was sponsored by Otsuka Pharmaceutical Development & Commercialization Inc., Princeton, NJ, USA, and H. Lundbeck LLC, Deerfield, IL, USA.

This work was sponsored by Alkermes, Inc.

This work was sponsored by Zevra Therapeutics

This work was sponsored by Jazz Pharmaceuticals

Introduction: This study compared the odds of cardiovascular (CV) conditions in patients with idiopathic hypersomnia (IH) versus matched non-IH controls.

This work was sponsored by AbbVie

Background:Post-hoc analysis investigated efficacy and tolerability of adjunctive cariprazine (CAR) in patients with major depressive disorder (MDD) using number needed to treat (NNT), number needed to harm (NNH), likelihood to be helped/harmed (LHH).

This work was sponsored by Karuna Therapeutics.

This trial was funded by Otsuka Pharmaceutical Development & Commercialization, Inc.

This work was sponsored by Intra-Cellular Therapies, Inc.

This work was sponsored by CVS Health Clinical Trial Services, LLC, Woonsocket, RI, USA<br>Sage Therapeutics, Inc., Cambridge, MA USA<br>Biogen Inc., Cambridge, MA USA

This study was funded by Avadel Pharmaceuticals.

This work was sponsored by Recognify Life Sciences and atai Life Sciences

In inpatient postpartum settings, psychiatrists are often asked to evaluate a mother's ability to care for her infant in urgent "maternal capacity consults" before discharge.

This work was sponsored by Otsuka Pharmaceutical Development & Commercialization Inc., Princeton, NJ, USA and H. Lundbeck LLC, Deerfield, IL, USA

This work was sponsored by Janssen Scientific Affairs, LLC

Synthetic Cannabinoids (SCs) have been linked to several cases of catatonia in patients without a pre-existing affective or psychotic disorder.

Male, 54 y.o., a successful chef, started at the age of 47 to display symptoms of a psychotic state. The patient reported the presence of lice under the scalp, felt their bites and movements, and believed that these are very special lice that can only be infected by pigeons.

This study was funded by Avadel Pharmaceuticals.

Background: Suicide is the tenth leading cause of overall death in the US. Despite the extensive array of literature about suicide-related visits to the emergency department (ED), little is known about the factors that predict revisits to the hospital for these issues.

This work was sponsored by Boston VA Healthcare System

This work was sponsored by Otsuka Pharmaceutical Development & Commercialization Inc. (Princeton, NJ, USA) and H. Lundbeck A/S (Valby, Denmark).

This work was sponsored by Jazz Pharmaceuticals

This study was sponsored by Alkermes, Inc.

With increasing awareness of how identity impacts mental health, there is a need to understand if and how race and sexual orientation influence the stigma surrounding the treatment of generalized anxiety disorder (GAD) and major depressive disorder (MDD).

This work was sponsored by Teva Branded Pharmaceutical Products R&D, Inc.

This study was sponsored by Otsuka Pharmaceutical Development & Commercialization Inc., Princeton, NJ, USA, and H. Lundbeck LLC, Deerfield, IL, USA.

This work was sponsored by Teva Branded Pharmaceutical Products R&D, Inc.

This work was supported by Otsuka Pharmaceutical Development & Commercialization Inc. (Princeton, NJ, USA) and H. Lundbeck A/S (Valby, Denmark)

Background: Recent evidence suggests that personalizing transcranial magnetic stimulation (TMS) to a person’s individual alpha frequency (IAF) (8, 9, 10, or 11 Hz) may yield better outcomes. Our question is: does a person’s IAF predict outcome?

This work was sponsored by AbbVie

Background: Post-hoc analysis evaluating efficacy of adjunctive cariprazine (CAR) treatment on anhedonia symptoms in patients with major depressive disorder (MDD).

This work was sponsored by H. Lundbeck A/S

This work was sponsored by H. Lundbeck A/S

This work was sponsored by Otsuka Canada Pharmaceutical Inc. (Saint-Laurent, Quebec, Canada) and Lundbeck Canada Inc. (Saint-Laurent, Quebec, Canada)

This work was sponsored by Jazz Pharmaceuticals

This work was sponsored by Axsome Therapeutics and Jazz Pharmaceuticals

This work was sponsored by Boehringer Ingelheim and Click Therapeutics.

Introduction

These studies are funded by Boehringer Ingelheim.

This work was sponsored by Janssen Scientific Affairs, LLC

This work was sponsored by Janssen Research & Development, LLC

This work was sponsored by Janssen Scientific Affairs, LLC

This study was funded by Funded by MAPS and Steven and Alexandra Cohen Foundation, Inc. and organized by MAPS PBC.

This work was sponsored by Otsuka Pharmaceutical Development & Commercialization Inc. (Princeton, NJ, USA) and H. Lundbeck A/S (Valby, Copenhagen, Denmark)

This study was funded by Teva Pharmaceuticals.

This work was sponsored by Indivior Inc.This study was funded by Teva Pharmaceuticals.

This work was sponsored by Intra-Cellular Therapies, Inc.

The ability to regulate emotions effectively has been associated with resilience to psychopathology. Emotion regulation difficulties have been proposed as a component of clinical disorders and are a primary target of a form of psychotherapy known as dialectical behavior therapy (DBT).

This work was sponsored by Cerevel Therapeutics

The pandemic was a major driving force that spurred telemedicine's rapid adoption and expansion.

This work was sponsored by Mindful Health Solutions

We thank the patients who participated. This study was funded by Janssen, medical writing by Costello Medical, UK.

This work was sponsored by Sage Therapeutics, Inc. and Biogen Inc.

Schizophrenia, depression, bipolar disorder, and anxiety are all serious mental health conditions that are highly prevalent amongst incarcerated patients.

This work was sponsored by Intra-Cellular Therapies, Inc.

This work was sponsored by Teva Pharmaceuticals

This work was sponsored by Myriad Genetics, Inc.

Introduction: Tinnitus exacerbation with opioid withdrawal and relief upon re-administration of opioids has not been described. Methods: Case report: A 37-year-old male presented with a persistent ringing sensation in his ears for three years after cessation of chronic heroin abuse.

This work was sponsored by Ironshore, manufacturer of DR/ER-MPH (formerly HLD200)

This work was sponsored by H. Lundbeck A/S

This study was funded by Sumitomo Pharma America (formerly Sunovion Pharmaceuticals Inc).

This work was sponsored by AbbVie

This work was sponsored by Alkermes, Inc.

This work was sponsored by Eastern Virginia Medical School

This work was sponsored by AbbVie

Objective: To evaluate the effects of cariprazine adjunctive to antidepressant therapy (ADT) on health-related quality of life (HRQoL) in patients with major depressive disorder (MDD).

This work was sponsored by Axsome Therapeutics

This study was funded by Teva Pharmaceuticals.

This work was sponsored by Eisai Inc.

This work was sponsored by Teva Branded Pharmaceutical Products R&D, Inc.

The purpose of this project is to examine the impact of exercise regimens in improving the symptoms of depression. Clinical depression is a mental health illness characterized by sadness, loss of interest or pleasure in activities, and numerous physical and emotional symptoms.

This work was sponsored by Axsome Therapeutics

This work was sponsored by Eisai Inc.

The individual studies herein were sponsored by Sage Therapeutics, Inc. (201B, MOUNTAIN); Sage Therapeutics, Inc., and Biogen Inc (WATERFALL); or Shionogi & Co., Ltd. (1818A3731).

This work was sponsored by AbbVie

This work was sponsored by Teva Branded Pharmaceutical Products R&D, Inc.

This work was sponsored by National Network of Depression Centers (NNDC) Geriatric Mood Disorders Task Group and the Depression and Bipolar Support Alliance (DBSA)

Currently, Binocular Vision Disorder (BVD) is not a differential diagnosis that appears on the radar of the majority of psychiatric providers. BVD is a vision disorder that currently can only be diagnosed and treated by a NeuroVisual Medicine Specialist.

This work was sponsored by Alkermes, Inc.

This work was sponsored by Alkermes, Inc.

Meningioma is slow growing tumor of meninges. The symptoms can be subtle and non-neurological leading to delay in diagnosis.

This work was sponsored by Janssen Scientific Affairs, LLC

Purpose: To describe long-term efficacy of esketamine nasal spray (ESK) in adults with treatment-resistant depression (TRD) dosed according to US prescribing information.

This work was sponsored by Janssen Research & Development, LLC

Aim: To assess long-term safety and efficacy of esketamine nasal spray in treatment-resistant depression (TRD).

This work was sponsored by Janssen Scientific Affairs, LLC

Purpose: To describe long-term safety of esketamine nasal spray (ESK) in adults with treatment-resistant depression (TRD) dosed according to US prescribing information.

This study was funded by Avadel Pharmaceuticals.

This work was sponsored by Teva Branded Pharmaceutical Products R&D, Inc.

This work was sponsored by Intra-Cellular Therapies, Inc.

This work was sponsored by Intra-Cellular Therapies, Inc.

Introduction: The optimal strategy for delivering TMS beyond acute treatment in patients who have achieved optimal clinical response remains unclear.

Medical Management of Capgras Syndrome with Underlying Lewy Body Dementia in an Elderly Patient with Mild Cognitive Impairment

This study was funded by Sage Therapeutics, Inc. and Biogen Inc. Medical writing and editorial support were provided by Humana Healthcare Research, Inc. and funded by Sage Therapeutics, Inc., and Biogen Inc.

This work was sponsored by Alkermes, Inc.

Objective: Evaluate use of Primary Care Path program for depression management in primary care clinical settings and its impact on shared decision-making (SDM), treatment, symptoms, and goal setting and attainment.

This study was funded by Multidisciplinary Association for Psychedelic Studies (MAPS) and organized by MAPS Public Benefit Corporation (PBC).

This work was sponsored by Alkermes, Inc.

This work was sponsored by Alkermes, Inc.

This work was sponsored by Alkermes, Inc.

This work was sponsored by Jazz Pharmaceuticals, with participation of the Hypersomnia Foundation

This work was sponsored by Sage Therapeutics, Inc. and Biogen, Inc.

The study reported in this abstract was funded by an educational grant from Takeda Pharmaceuticals U.S.A., Inc.

This study was funded by Avadel Pharmaceuticals.

This work was sponsored by Boehringer Ingelheim

Rationale

This work was sponsored by Medscape Education

Objective: To examine whether multiple continuing medical education (CME) interventions can improve provider knowledge, competence, and confidence related to pharmacogenomic (PGx) testing for patients with major depressive disorder (MDD).

This work was sponsored by Otsuka Pharmaceutical Development & Commercialization Inc. (Princeton, NJ, USA) and H. Lundbeck A/S (Valby, Denmark).

This work was sponsored by Shandong Luye Pharmaceutical Co., Ltd.

Burnout can have a detrimental impact on both medical providers and patients. We quantified burnout in the PA workforce using a robust national 2021 dataset (111,726) from the National Commission on Certification of Physician Assistants (NCCPA).

This work was sponsored by Jazz Pharmaceuticals, with participation of the Hypersomnia Foundation

This work was sponsored by Shandong Luye Pharmaceutical Co., Ltd.

This work was sponsored by Medscape Education

Objective: Ketamine has shown promise as a rapidly acting antidepressant, but real-world effectiveness rates are lower than those reported in clinical trials.

Despite the abundance of approved antidepressants, the majority of depressed patients do not respond to their first prescribed antidepressant, with >30% not responding to subsequent drugs.

Supported by funding from Sumitomo Pharma America, Inc. and Otsuka Pharmaceuticals Development & Commercialization, Inc.

This work was sponsored by Teva Branded Pharmaceutical Products R&D, Inc.

Background: Although long-acting injectable antipsychotics (LAIs) improve adherence and reduce schizophrenia relapse rates, they remain underutilized in clinical practice.

Sexual dysfunction is a prevalent issue that can impact both men and women, leading to significant challenges in relationships. Among these dysfunctions, Premature Ejaculation (PE) and Female Orgasmic Disorder (FOD) are two conditions that are often interconnected.

This work was sponsored by University of Arizona, College of Medicine - Phoenix

This work was sponsored by Sumitomo Pharma America Inc.

This work was sponsored by Supernus Pharmaceuticals, Inc.

This work was sponsored by Janssen Global Services, LLC

This work was sponsored by Project Vida Health Clinic (FQHC)

This work was sponsored by Teva Branded Pharmaceutical Products R&D, Inc.

This work was sponsored by Teva Branded Pharmaceutical Products R&D, Inc.

This work was sponsored by Teva Branded Pharmaceutical Products R&D, Inc.

This work was sponsored by Takeda Pharmaceuticals U.S.A., Inc.

This work was sponsored by Janssen Scientific Affairs, LLC

This work was sponsored by Janssen Research & Development, LLC

It is well documented that clozapine is under-utilized in the US, even though it is the most effective medication for treatment-resistant schizophrenia. In addition, clinical assessments of a patient's drug status have been proven inaccurate.

This work was sponsored by Karuna Therapeutics

This work was sponsored by Jazz Pharmaceuticals

This work was sponsored by Sage Therapeutics, Inc., and Biogen Inc.

Given the prevalence of Obsessive Compulsive Disorder (OCD) in the United States, the need for accurate screening tools has progressively risen. In order to meet this need, existing screening tools must be re-evaluated to optimize their efficacy.

This work was sponsored by American Association of Psychiatric Pharmacists (AAPP)

This work was sponsored by Takeda Pharmaceuticals U.S.A., Inc., and Lundbeck LLC

This work was sponsored by Teva Branded Pharmaceutical Products R&D, Inc.

This work was sponsored by Axsome Therapeutics

This work was sponsored by Axsome Therapeutics and Jazz Pharmaceuticals

Medication for opioid use disorder (OUD) with methadone or buprenorphine/naloxone is recommended for pregnant women with OUD.

This study was funded by Axsome Therapeutics and Jazz Pharmaceuticals. This presentation was supported by Axsome Therapeutics and Pharmanovia.

This work was sponsored by Neurocrine Biosciences, Inc.

This work was sponsored by Neurocrine Biosciences Inc.

Residual sedation from hypnotic drugs is a causal factor for many motor vehicle accidents.

Generalized Anxiety Disorder (GAD) is among the most prevalent mental health problems in children and adolescents. (SSRIs) are among the main treatment modalities that are used in pediatric anxiety.

Our hypothesis postulates that those who had employer-based insurance were negatively affected and those who had public insurance were positively affected. Those who were on public insurance may not have been affected, however, Many of those who lost job-based health insurance.

Background: IDgenetix is a pharmacogenomics (PGx) test that incorporates the results of a multi-gene variant panel with drug-drug interactions (DDI) and lifestyle factors to provide medication recommendations for patients diagnosed with major depressive disorder (MDD) or other mental illnesses.

This work was sponsored by AbbVie

With the development of the Adverse Childhood Experiences (ACE) questionnaire, Felitti et al. (1998) established that childhood trauma has a wide-ranging impact on adult health.

Although literature supports the role of emotion dysregulation and pain endurance as independent predictors of non-suicidal self-injury (NSSI) and disordered eating behaviors, there remains little investigation of the interaction of these variables.

Background: Digital applications are having a long-lasting impact on our day-to-day lives, and digital technologies like robots are becoming increasingly omnipresent in our modern world. In the psychiatric setting the SAR “Pepper” holds a lot of potential. Objectives:

We thank the patients who participated. This study was funded by Janssen, medical writing by Costello Medical, UK.

This work was sponsored by Department of Veterans Affairs / Veterans Health Administration

Background: The Russian invasion of Ukraine has greatly affected access to mental health services in the country. To address this, TeleHelp Ukraine, a non-profit organization, offers telemedicine visits and mental health support through a secure telemedicine platform.

This work was sponsored by Teva Branded Pharmaceutical Products R&D, Inc.

This work was sponsored by Alkermes, Inc.

This work was sponsored by Teva Branded Pharmaceutical Products R&D, Inc.

This work was sponsored by Janssen Scientific Affairs, LLC

This work was sponsored by Janssen Scientific Affairs, LLC

This work was sponsored by Sage Therapeutics, Inc. and Biogen Inc.

This work was sponsored by Otsuka Pharmaceutical

This work was supported by Otsuka Pharmaceutical Development & Commercialization, Inc. Princeton, NJ, USA and Lundbeck LLC. DH and SKare employees of Otsuka Pharmaceutical Development & Commercialization Inc., Princeton, NJ, USA. BT is an employee of Lundbeck LLC, Deerfield, IL, USA.

This work was sponsored by AbbVie

Background: Tardive dyskinesia is a persistent, often irreversible movement disorder that may develop after chronic, cumulative exposure to antipsychotics.

This work was sponsored by Lehigh Valley Health Network

This work was sponsored by Myriad Genetics, Inc.

This work was sponsored by Neurocrine Biosciences, Inc.

We would be honored to present our program, Veterans Intensive Primary Care Mental Health Integration Bootcamp (VIP Bootcamp) with some initial pilot data at your conference.

This work was sponsored by Supernus Pharmaceuticals, Inc.

Introduction: Catatonia is a psychomotor syndrome with well-defined clinical characteristics, although the neurological mechanisms involved remain unknown.

This study was sponsored by Sage Therapeutics, Inc., and Biogen Inc.