Mark Todtenkopf, PhD

A Combination of Olanzapine and Samidorphan in Adults With Schizophrenia and Bipolar I Disorder: Overview of Clinical Data

Objectives: Olanzapine effectively treats schizophrenia and bipolar I disorder (BD-I); however, its use is hindered by significant weight gain. A combination of olanzapine and samidorphan...

Mark Todtenkopf , PhD;

Lauren DiPetrillo , PhD;

Hannah Cummings , PhD;

Leslie Citrome , MD;

Adam Simmons , MPH;

David McDonnell , MD;

Ying Jiang , PhD;

Lei Sun , PhD;

Christine Graham , PhD;

Bernard Silverman , MD;

10/08/2020

Opioid Antagonists: Clinical Utility, Pharmacology, and Safety and Tolerability

Pharmacology, clinical uses, and safety/tolerability of FDA-approved opioid antagonists are reviewed. Opioid antagonists treat opioid overdose, alcohol/opioid use disorder, and opioid-ind...

Mark Todtenkopf , PhD;

10/26/2023