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Population Study of Psoriasis Prevalence and Associated Comorbidities
According to a study published in the Journal of Clinical Medicine, there are significant associations between psoriasis and cardiac, psychological, and musculoskeletal comorbidities.
Researchers focused on investigating the prevalence of psoriasis in a large-scale, population-based cohort and describing its comorbidities. The study utilized electronic health records from the EpiChron Cohort, encompassing 31,178 individuals diagnosed with psoriasis in 2019.
The prevalence of psoriasis in the cohort was found to be 2.84%, with a higher prevalence in men (3.31% vs 2.43%). Chronic comorbidities associated with psoriasis were extensively examined, revealing that disorders of lipid metabolism (35.87%), hypertension (35.50%), and other nutritional-endocrine-metabolic disorders (21.79%) were the most frequent.
The study employed logistic regression models to analyze the likelihood of comorbidities occurring with psoriasis. Notably, conditions significantly associated with psoriasis included tuberculosis (odds ratio [OR], 2.36; 95% CI: 1.24–4.49) and cystic fibrosis (OR, 2.15; 95% CI: 1.25–3.69), among others. However, the study did not find a significant association between psoriasis and hypertension or neoplasms (OR, 0.90; 95% CI: 0.86–0.95).
In conclusion, this study highlighted the prevalence of psoriasis in a sizable cohort and shed light on its associations with various comorbidities. The findings indicated significant links between psoriasis and conditions affecting the cardiac, psychological, and musculoskeletal systems. The comprehensive analysis contributes valuable insights into the broader health implications of psoriasis, providing a foundation for further research and potential improvements in the management of this chronic skin disease.
Reference
Almenara-Blasco M, Gracia-Cazaña T, Poblador-Plou B, et al. Multimorbidity of psoriasis: a large-scale population study of its associated comorbidities. J Clin Med. Published online January 16, 2024. doi:10.3390/jcm13020492
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