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Board Review

The Dermatologist’s Board Review - June

June 2015

The contents of these questions are taken from the Galderma Pre-Board Webinar. The Pre-Board Webinar is now an on-line course, which is  available from April 15, 2015 through July 31, 2015. For details, go to www.galdermausa.com/Our-Commitment/Resident-Education.aspx 

 

1. Which statement about this disease is true?

a)The highest annual incidence is observed in northern European countries

b)The annual incidence among black Americans is 5 to 10 times higher than among white Americans 

c)The peak incidence in blacks is earlier than in other ethnic groups

d)The disease runs a more benign course in black Americans than in white Americans 

e) The incidence of erythema nodosum is about 25%

2. This disorder is the leading cause of acquired heart disease in children in developed countries. The incidence is highest in:

a) India 

b) Taiwan 

c) Korea

d) Japan 

e) United States

3. This patient developed a generalized eczematous eruption after ingestion of cetirizine. Patch testing would most likely show a positive reaction to:  

a) Tetramethylthiuram 

b) Nickel sulfate

c) Potassium dichromate 

d) Ethylenediamine

e) Balsam of Peru

4. What is a documented systemic manifestation of this condition?  

a) Colon cancer

b) Parathyroid adenoma 

c) Insulin-resistant diabetes

d) Monoclonal gammopathy 

e) Pheochromocytoma 

To learn the answers, go to page 2

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1. Sarcoidosis 

Which statement about this disease is true? 

a) The highest annual incidence is observed in northern European countries

The highest annual incidence of sarcoidosis has been observed in northern European countries. In the United States, the incidence among black Americans is approximately 3 times that of white Americans. In black Americans, the peak incidence occurs later in life (in the fourth decade) as compared with other ethnic groups. The disease is more likely to be chronic and fatal in black Americans. Erythema nodosum occurs in approximately 10% of patients with sarcoidosis and usually lasts for about 2 weeks. 

References

Haimovic A, Sanchez M, Judson MA, Prystowsky S. Sarcoidosis: a comprehensive review and update for the dermatologist: part I. Cutaneous disease. J Am Acad Dermatol. 2012;66(5):699.e1-18; quiz 717-718. 

Haimovic A, Sanchez M, Judson MA, Prystowsky S. Sarcoidosis: a comprehensive review and update for the dermatologist: part II. Extracutaneous disease. J Am Acad Dermatol. 2012;66(5):719.e1.-10; quiz 729-730. 

O’Regan A, Berman JS. Sarcoidosis. Ann Intern Med. 2012;156(9):ITC5-1, ITC5-2, ITC5-3, ITC5-4, ITC5-5, ITC5-6, ITC5-7, ITC5-8, ITC5-9, ITC5-10, ITC5-11, ITC5-12, ITC5-13, ITC5-14, ITC5-15; quiz ITC5-16. 

Dempsey OJ, Paterson EW, Kerr KM, Denison AR. Sarcoidosis. BMJ. 2009;339:b3206. 

2. Kawasaki Disease  

This disorder is the leading cause of acquired heart disease in children in developed countries. The incidence is the highest in:

d) Japan

Kawasaki disease is up to 20 times more common in Northeast Asians than in Caucasians, with the highest rates being reported in Japan. In 2005 to 2006, the annual incidence in Japan was 184/100,000 in children under 5 years of age. 

References

Holve TJ, Patel A, Chau Q, Marks AR, Meadows A, Zaroff JG. Long-term cardiovascular outcomes in survivors of Kawasaki disease. Pediatrics. 2014;133(2):e305-311. 

Scuccimarri R. Kawasaki disease. Pediatr Clin North Am. 2012;59(2):425-445. 

Harnden A, Takahashi M, Burgner D. Kawasaki disease. BMJ. 2009;338:b1514.

3. Systematic Allergic Contact Dermatitis 

This patient developed a generalized eczematous eruption after ingestion of cetirizine. Patch testing would most likely show a positive reaction to:

d) Ethylenediamine 

Cetirizine and hydroxyzine are structurally related to ethylenediamine, and their ingestion can provoke systemic allergic contact dermatitis. 

Reference

Veien NK. Systemic contact dermatitis. Int J Dermatol. 2011:50(12):1445-1456. 

4. Scleromyxedema (Lichen Myxedematosus) 

What is a documented systematic manifestation of this condition?

d) Monoclonal gammopathy 

Scleromyxedema is frequently associated with a monoclonal gammopathy. Intravenous immunoglobulins are a newly described treatment. 

Reference

Bolton JG, Satter EK. An interstitial granulomatous pattern in localized lichen myxedematosus with associated monoclonal gammopathy. J Cutan Pathol. 2012;39(3):395-398. 

 

Bruce Thiers, MD, FAAD, is professor and chairman of the Department of Dermatology and Dermatologic Surgery at the Medical University of South Carolina in Charleston, SC.

The contents of these questions are taken from the Galderma Pre-Board Webinar. The Pre-Board Webinar is now an on-line course, which is  available from April 15, 2015 through July 31, 2015. For details, go to www.galdermausa.com/Our-Commitment/Resident-Education.aspx 

 

1. Which statement about this disease is true?

a)The highest annual incidence is observed in northern European countries

b)The annual incidence among black Americans is 5 to 10 times higher than among white Americans 

c)The peak incidence in blacks is earlier than in other ethnic groups

d)The disease runs a more benign course in black Americans than in white Americans 

e) The incidence of erythema nodosum is about 25%

2. This disorder is the leading cause of acquired heart disease in children in developed countries. The incidence is highest in:

a) India 

b) Taiwan 

c) Korea

d) Japan 

e) United States

3. This patient developed a generalized eczematous eruption after ingestion of cetirizine. Patch testing would most likely show a positive reaction to:  

a) Tetramethylthiuram 

b) Nickel sulfate

c) Potassium dichromate 

d) Ethylenediamine

e) Balsam of Peru

4. What is a documented systemic manifestation of this condition?  

a) Colon cancer

b) Parathyroid adenoma 

c) Insulin-resistant diabetes

d) Monoclonal gammopathy 

e) Pheochromocytoma 

1. Sarcoidosis 

Which statement about this disease is true? 

a) The highest annual incidence is observed in northern European countries

The highest annual incidence of sarcoidosis has been observed in northern European countries. In the United States, the incidence among black Americans is approximately 3 times that of white Americans. In black Americans, the peak incidence occurs later in life (in the fourth decade) as compared with other ethnic groups. The disease is more likely to be chronic and fatal in black Americans. Erythema nodosum occurs in approximately 10% of patients with sarcoidosis and usually lasts for about 2 weeks. 

References

Haimovic A, Sanchez M, Judson MA, Prystowsky S. Sarcoidosis: a comprehensive review and update for the dermatologist: part I. Cutaneous disease. J Am Acad Dermatol. 2012;66(5):699.e1-18; quiz 717-718. 

Haimovic A, Sanchez M, Judson MA, Prystowsky S. Sarcoidosis: a comprehensive review and update for the dermatologist: part II. Extracutaneous disease. J Am Acad Dermatol. 2012;66(5):719.e1.-10; quiz 729-730. 

O’Regan A, Berman JS. Sarcoidosis. Ann Intern Med. 2012;156(9):ITC5-1, ITC5-2, ITC5-3, ITC5-4, ITC5-5, ITC5-6, ITC5-7, ITC5-8, ITC5-9, ITC5-10, ITC5-11, ITC5-12, ITC5-13, ITC5-14, ITC5-15; quiz ITC5-16. 

Dempsey OJ, Paterson EW, Kerr KM, Denison AR. Sarcoidosis. BMJ. 2009;339:b3206. 

2. Kawasaki Disease  

This disorder is the leading cause of acquired heart disease in children in developed countries. The incidence is the highest in:

d) Japan

Kawasaki disease is up to 20 times more common in Northeast Asians than in Caucasians, with the highest rates being reported in Japan. In 2005 to 2006, the annual incidence in Japan was 184/100,000 in children under 5 years of age. 

References

Holve TJ, Patel A, Chau Q, Marks AR, Meadows A, Zaroff JG. Long-term cardiovascular outcomes in survivors of Kawasaki disease. Pediatrics. 2014;133(2):e305-311. 

Scuccimarri R. Kawasaki disease. Pediatr Clin North Am. 2012;59(2):425-445. 

Harnden A, Takahashi M, Burgner D. Kawasaki disease. BMJ. 2009;338:b1514.

3. Systematic Allergic Contact Dermatitis 

This patient developed a generalized eczematous eruption after ingestion of cetirizine. Patch testing would most likely show a positive reaction to:

d) Ethylenediamine 

Cetirizine and hydroxyzine are structurally related to ethylenediamine, and their ingestion can provoke systemic allergic contact dermatitis. 

Reference

Veien NK. Systemic contact dermatitis. Int J Dermatol. 2011:50(12):1445-1456. 

4. Scleromyxedema (Lichen Myxedematosus) 

What is a documented systematic manifestation of this condition?

d) Monoclonal gammopathy 

Scleromyxedema is frequently associated with a monoclonal gammopathy. Intravenous immunoglobulins are a newly described treatment. 

Reference

Bolton JG, Satter EK. An interstitial granulomatous pattern in localized lichen myxedematosus with associated monoclonal gammopathy. J Cutan Pathol. 2012;39(3):395-398. 

 

Bruce Thiers, MD, FAAD, is professor and chairman of the Department of Dermatology and Dermatologic Surgery at the Medical University of South Carolina in Charleston, SC.

The contents of these questions are taken from the Galderma Pre-Board Webinar. The Pre-Board Webinar is now an on-line course, which is  available from April 15, 2015 through July 31, 2015. For details, go to www.galdermausa.com/Our-Commitment/Resident-Education.aspx 

 

1. Which statement about this disease is true?

a)The highest annual incidence is observed in northern European countries

b)The annual incidence among black Americans is 5 to 10 times higher than among white Americans 

c)The peak incidence in blacks is earlier than in other ethnic groups

d)The disease runs a more benign course in black Americans than in white Americans 

e) The incidence of erythema nodosum is about 25%

2. This disorder is the leading cause of acquired heart disease in children in developed countries. The incidence is highest in:

a) India 

b) Taiwan 

c) Korea

d) Japan 

e) United States

3. This patient developed a generalized eczematous eruption after ingestion of cetirizine. Patch testing would most likely show a positive reaction to:  

a) Tetramethylthiuram 

b) Nickel sulfate

c) Potassium dichromate 

d) Ethylenediamine

e) Balsam of Peru

4. What is a documented systemic manifestation of this condition?  

a) Colon cancer

b) Parathyroid adenoma 

c) Insulin-resistant diabetes

d) Monoclonal gammopathy 

e) Pheochromocytoma 

,

The contents of these questions are taken from the Galderma Pre-Board Webinar. The Pre-Board Webinar is now an on-line course, which is  available from April 15, 2015 through July 31, 2015. For details, go to www.galdermausa.com/Our-Commitment/Resident-Education.aspx 

 

1. Which statement about this disease is true?

a)The highest annual incidence is observed in northern European countries

b)The annual incidence among black Americans is 5 to 10 times higher than among white Americans 

c)The peak incidence in blacks is earlier than in other ethnic groups

d)The disease runs a more benign course in black Americans than in white Americans 

e) The incidence of erythema nodosum is about 25%

2. This disorder is the leading cause of acquired heart disease in children in developed countries. The incidence is highest in:

a) India 

b) Taiwan 

c) Korea

d) Japan 

e) United States

3. This patient developed a generalized eczematous eruption after ingestion of cetirizine. Patch testing would most likely show a positive reaction to:  

a) Tetramethylthiuram 

b) Nickel sulfate

c) Potassium dichromate 

d) Ethylenediamine

e) Balsam of Peru

4. What is a documented systemic manifestation of this condition?  

a) Colon cancer

b) Parathyroid adenoma 

c) Insulin-resistant diabetes

d) Monoclonal gammopathy 

e) Pheochromocytoma 

To learn the answers, go to page 2

{{pagebreak}}

1. Sarcoidosis 

Which statement about this disease is true? 

a) The highest annual incidence is observed in northern European countries

The highest annual incidence of sarcoidosis has been observed in northern European countries. In the United States, the incidence among black Americans is approximately 3 times that of white Americans. In black Americans, the peak incidence occurs later in life (in the fourth decade) as compared with other ethnic groups. The disease is more likely to be chronic and fatal in black Americans. Erythema nodosum occurs in approximately 10% of patients with sarcoidosis and usually lasts for about 2 weeks. 

References

Haimovic A, Sanchez M, Judson MA, Prystowsky S. Sarcoidosis: a comprehensive review and update for the dermatologist: part I. Cutaneous disease. J Am Acad Dermatol. 2012;66(5):699.e1-18; quiz 717-718. 

Haimovic A, Sanchez M, Judson MA, Prystowsky S. Sarcoidosis: a comprehensive review and update for the dermatologist: part II. Extracutaneous disease. J Am Acad Dermatol. 2012;66(5):719.e1.-10; quiz 729-730. 

O’Regan A, Berman JS. Sarcoidosis. Ann Intern Med. 2012;156(9):ITC5-1, ITC5-2, ITC5-3, ITC5-4, ITC5-5, ITC5-6, ITC5-7, ITC5-8, ITC5-9, ITC5-10, ITC5-11, ITC5-12, ITC5-13, ITC5-14, ITC5-15; quiz ITC5-16. 

Dempsey OJ, Paterson EW, Kerr KM, Denison AR. Sarcoidosis. BMJ. 2009;339:b3206. 

2. Kawasaki Disease  

This disorder is the leading cause of acquired heart disease in children in developed countries. The incidence is the highest in:

d) Japan

Kawasaki disease is up to 20 times more common in Northeast Asians than in Caucasians, with the highest rates being reported in Japan. In 2005 to 2006, the annual incidence in Japan was 184/100,000 in children under 5 years of age. 

References

Holve TJ, Patel A, Chau Q, Marks AR, Meadows A, Zaroff JG. Long-term cardiovascular outcomes in survivors of Kawasaki disease. Pediatrics. 2014;133(2):e305-311. 

Scuccimarri R. Kawasaki disease. Pediatr Clin North Am. 2012;59(2):425-445. 

Harnden A, Takahashi M, Burgner D. Kawasaki disease. BMJ. 2009;338:b1514.

3. Systematic Allergic Contact Dermatitis 

This patient developed a generalized eczematous eruption after ingestion of cetirizine. Patch testing would most likely show a positive reaction to:

d) Ethylenediamine 

Cetirizine and hydroxyzine are structurally related to ethylenediamine, and their ingestion can provoke systemic allergic contact dermatitis. 

Reference

Veien NK. Systemic contact dermatitis. Int J Dermatol. 2011:50(12):1445-1456. 

4. Scleromyxedema (Lichen Myxedematosus) 

What is a documented systematic manifestation of this condition?

d) Monoclonal gammopathy 

Scleromyxedema is frequently associated with a monoclonal gammopathy. Intravenous immunoglobulins are a newly described treatment. 

Reference

Bolton JG, Satter EK. An interstitial granulomatous pattern in localized lichen myxedematosus with associated monoclonal gammopathy. J Cutan Pathol. 2012;39(3):395-398. 

 

Bruce Thiers, MD, FAAD, is professor and chairman of the Department of Dermatology and Dermatologic Surgery at the Medical University of South Carolina in Charleston, SC.

The contents of these questions are taken from the Galderma Pre-Board Webinar. The Pre-Board Webinar is now an on-line course, which is  available from April 15, 2015 through July 31, 2015. For details, go to www.galdermausa.com/Our-Commitment/Resident-Education.aspx 

 

1. Which statement about this disease is true?

a)The highest annual incidence is observed in northern European countries

b)The annual incidence among black Americans is 5 to 10 times higher than among white Americans 

c)The peak incidence in blacks is earlier than in other ethnic groups

d)The disease runs a more benign course in black Americans than in white Americans 

e) The incidence of erythema nodosum is about 25%

2. This disorder is the leading cause of acquired heart disease in children in developed countries. The incidence is highest in:

a) India 

b) Taiwan 

c) Korea

d) Japan 

e) United States

3. This patient developed a generalized eczematous eruption after ingestion of cetirizine. Patch testing would most likely show a positive reaction to:  

a) Tetramethylthiuram 

b) Nickel sulfate

c) Potassium dichromate 

d) Ethylenediamine

e) Balsam of Peru

4. What is a documented systemic manifestation of this condition?  

a) Colon cancer

b) Parathyroid adenoma 

c) Insulin-resistant diabetes

d) Monoclonal gammopathy 

e) Pheochromocytoma 

1. Sarcoidosis 

Which statement about this disease is true? 

a) The highest annual incidence is observed in northern European countries

The highest annual incidence of sarcoidosis has been observed in northern European countries. In the United States, the incidence among black Americans is approximately 3 times that of white Americans. In black Americans, the peak incidence occurs later in life (in the fourth decade) as compared with other ethnic groups. The disease is more likely to be chronic and fatal in black Americans. Erythema nodosum occurs in approximately 10% of patients with sarcoidosis and usually lasts for about 2 weeks. 

References

Haimovic A, Sanchez M, Judson MA, Prystowsky S. Sarcoidosis: a comprehensive review and update for the dermatologist: part I. Cutaneous disease. J Am Acad Dermatol. 2012;66(5):699.e1-18; quiz 717-718. 

Haimovic A, Sanchez M, Judson MA, Prystowsky S. Sarcoidosis: a comprehensive review and update for the dermatologist: part II. Extracutaneous disease. J Am Acad Dermatol. 2012;66(5):719.e1.-10; quiz 729-730. 

O’Regan A, Berman JS. Sarcoidosis. Ann Intern Med. 2012;156(9):ITC5-1, ITC5-2, ITC5-3, ITC5-4, ITC5-5, ITC5-6, ITC5-7, ITC5-8, ITC5-9, ITC5-10, ITC5-11, ITC5-12, ITC5-13, ITC5-14, ITC5-15; quiz ITC5-16. 

Dempsey OJ, Paterson EW, Kerr KM, Denison AR. Sarcoidosis. BMJ. 2009;339:b3206. 

2. Kawasaki Disease  

This disorder is the leading cause of acquired heart disease in children in developed countries. The incidence is the highest in:

d) Japan

Kawasaki disease is up to 20 times more common in Northeast Asians than in Caucasians, with the highest rates being reported in Japan. In 2005 to 2006, the annual incidence in Japan was 184/100,000 in children under 5 years of age. 

References

Holve TJ, Patel A, Chau Q, Marks AR, Meadows A, Zaroff JG. Long-term cardiovascular outcomes in survivors of Kawasaki disease. Pediatrics. 2014;133(2):e305-311. 

Scuccimarri R. Kawasaki disease. Pediatr Clin North Am. 2012;59(2):425-445. 

Harnden A, Takahashi M, Burgner D. Kawasaki disease. BMJ. 2009;338:b1514.

3. Systematic Allergic Contact Dermatitis 

This patient developed a generalized eczematous eruption after ingestion of cetirizine. Patch testing would most likely show a positive reaction to:

d) Ethylenediamine 

Cetirizine and hydroxyzine are structurally related to ethylenediamine, and their ingestion can provoke systemic allergic contact dermatitis. 

Reference

Veien NK. Systemic contact dermatitis. Int J Dermatol. 2011:50(12):1445-1456. 

4. Scleromyxedema (Lichen Myxedematosus) 

What is a documented systematic manifestation of this condition?

d) Monoclonal gammopathy 

Scleromyxedema is frequently associated with a monoclonal gammopathy. Intravenous immunoglobulins are a newly described treatment. 

Reference

Bolton JG, Satter EK. An interstitial granulomatous pattern in localized lichen myxedematosus with associated monoclonal gammopathy. J Cutan Pathol. 2012;39(3):395-398. 

 

Bruce Thiers, MD, FAAD, is professor and chairman of the Department of Dermatology and Dermatologic Surgery at the Medical University of South Carolina in Charleston, SC.

1. Sarcoidosis 

Which statement about this disease is true? 

a) The highest annual incidence is observed in northern European countries

The highest annual incidence of sarcoidosis has been observed in northern European countries. In the United States, the incidence among black Americans is approximately 3 times that of white Americans. In black Americans, the peak incidence occurs later in life (in the fourth decade) as compared with other ethnic groups. The disease is more likely to be chronic and fatal in black Americans. Erythema nodosum occurs in approximately 10% of patients with sarcoidosis and usually lasts for about 2 weeks. 

References

Haimovic A, Sanchez M, Judson MA, Prystowsky S. Sarcoidosis: a comprehensive review and update for the dermatologist: part I. Cutaneous disease. J Am Acad Dermatol. 2012;66(5):699.e1-18; quiz 717-718. 

Haimovic A, Sanchez M, Judson MA, Prystowsky S. Sarcoidosis: a comprehensive review and update for the dermatologist: part II. Extracutaneous disease. J Am Acad Dermatol. 2012;66(5):719.e1.-10; quiz 729-730. 

O’Regan A, Berman JS. Sarcoidosis. Ann Intern Med. 2012;156(9):ITC5-1, ITC5-2, ITC5-3, ITC5-4, ITC5-5, ITC5-6, ITC5-7, ITC5-8, ITC5-9, ITC5-10, ITC5-11, ITC5-12, ITC5-13, ITC5-14, ITC5-15; quiz ITC5-16. 

Dempsey OJ, Paterson EW, Kerr KM, Denison AR. Sarcoidosis. BMJ. 2009;339:b3206. 

2. Kawasaki Disease  

This disorder is the leading cause of acquired heart disease in children in developed countries. The incidence is the highest in:

d) Japan

Kawasaki disease is up to 20 times more common in Northeast Asians than in Caucasians, with the highest rates being reported in Japan. In 2005 to 2006, the annual incidence in Japan was 184/100,000 in children under 5 years of age. 

References

Holve TJ, Patel A, Chau Q, Marks AR, Meadows A, Zaroff JG. Long-term cardiovascular outcomes in survivors of Kawasaki disease. Pediatrics. 2014;133(2):e305-311. 

Scuccimarri R. Kawasaki disease. Pediatr Clin North Am. 2012;59(2):425-445. 

Harnden A, Takahashi M, Burgner D. Kawasaki disease. BMJ. 2009;338:b1514.

3. Systematic Allergic Contact Dermatitis 

This patient developed a generalized eczematous eruption after ingestion of cetirizine. Patch testing would most likely show a positive reaction to:

d) Ethylenediamine 

Cetirizine and hydroxyzine are structurally related to ethylenediamine, and their ingestion can provoke systemic allergic contact dermatitis. 

Reference

Veien NK. Systemic contact dermatitis. Int J Dermatol. 2011:50(12):1445-1456. 

4. Scleromyxedema (Lichen Myxedematosus) 

What is a documented systematic manifestation of this condition?

d) Monoclonal gammopathy 

Scleromyxedema is frequently associated with a monoclonal gammopathy. Intravenous immunoglobulins are a newly described treatment. 

Reference

Bolton JG, Satter EK. An interstitial granulomatous pattern in localized lichen myxedematosus with associated monoclonal gammopathy. J Cutan Pathol. 2012;39(3):395-398. 

 

Bruce Thiers, MD, FAAD, is professor and chairman of the Department of Dermatology and Dermatologic Surgery at the Medical University of South Carolina in Charleston, SC.