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Clostridioides difficile Topic Center

Featured Article

News
Fecal Microbiota Transplant for Patients With IBD and rCDI: Safety and Efficacy
03/28/2024

Emry Lloyd

Emry Lloyd
Patients with recurrent Clostridioides difficile infection have shown significant results when administered a fecal microbiota transplant. This study evaluated the safety and efficacy of using a fecal microbiota transplant for patients with...
Patients with recurrent Clostridioides difficile infection have shown significant results when administered a fecal microbiota transplant. This study evaluated the safety and efficacy of using a fecal microbiota transplant for patients with...
Patients with recurrent...
03/28/2024
First Report Managed Care
News
Two-Step Testing Linked With Lower Rate of CDI Treatment in Colonized Patients
03/14/2024
Switching to two-step algorithm testing for Clostridioides difficile infection correlated with lower rates of treatment, helping to differentiate colonization from active infection, according to a study published in Clinical Microbiology and...
Switching to two-step algorithm testing for Clostridioides difficile infection correlated with lower rates of treatment, helping to differentiate colonization from active infection, according to a study published in Clinical Microbiology and...
Switching to two-step algorithm...
03/14/2024
First Report Managed Care
News
HexSDF and HexRK are Required for Clostridioides difficile Synthesis, Which Impacts Resistance to Daptomycin and Bacitracin
11/15/2023
“C difficile is a major cause of hospital-acquired diarrhea and represents an urgent concern due to the prevalence of antibiotic resistance and the rate of recurrent infections,” wrote Anthony Pannullo, Department of Microbiology and...
“C difficile is a major cause of hospital-acquired diarrhea and represents an urgent concern due to the prevalence of antibiotic resistance and the rate of recurrent infections,” wrote Anthony Pannullo, Department of Microbiology and...
“C difficile is a major cause of...
11/15/2023
First Report Managed Care
Quiz
CDI Risk Factors
10/23/2023
What is the primary risk factor for Clostridioides difficile infection?
What is the primary risk factor for Clostridioides difficile infection?
What is the primary risk factor...
10/23/2023
First Report Managed Care
alpesh amin
Podcasts
How Does CDI Impact Health Care Utilization, Costs in Older Patients?
10/23/2023
Alpesh Amin, MD, MBA , professor and chair, University of California, discusses the results of a recent study, and explains why better treatments to reduce primary C difficile infection and recurrences in older adults can lower the mortality...
Alpesh Amin, MD, MBA , professor and chair, University of California, discusses the results of a recent study, and explains why better treatments to reduce primary C difficile infection and recurrences in older adults can lower the mortality...
Alpesh Amin, MD, MBA , professor...
10/23/2023
First Report Managed Care
Literature Review
Promising Outcomes for SER-109: A New Approach to Managing Recurrent CDI
10/23/2023
Not only does SER-109 effectively treat CDI, but results show that it can even reduce recurrence. A major benefit when it comes to associated health care costs for patients.
Not only does SER-109 effectively treat CDI, but results show that it can even reduce recurrence. A major benefit when it comes to associated health care costs for patients.
Not only does SER-109...
10/23/2023
First Report Managed Care
News
Comprehensive C difficile Infection Management Approach
10/17/2023
“Clinical treatment and management need to be multifaceted and consider not just pharmaceutical intervention but a holistic approach to the patient’s experience both during and after CDI, acknowledging the potential psychological and social...
“Clinical treatment and management need to be multifaceted and consider not just pharmaceutical intervention but a holistic approach to the patient’s experience both during and after CDI, acknowledging the potential psychological and social...
“Clinical treatment and...
10/17/2023
First Report Managed Care
News
Navigating CDI Prevention Implementation: Frontline Insights from VA Health Care Facilities
10/11/2023
This research examines the key factors influencing Clostridioides difficile infection (CDI) prevention practices, highlighting the role of organizational commitment, communication, standardization, and the limitations of role hierarchies...
This research examines the key factors influencing Clostridioides difficile infection (CDI) prevention practices, highlighting the role of organizational commitment, communication, standardization, and the limitations of role hierarchies...
This research examines the key...
10/11/2023
First Report Managed Care
News
Study Identifies Challenges and Improvement Opportunities Relating to Faecal Microbiota Transplantation for C difficile Infections
10/02/2023
A comprehensive understanding of how to develop and cultivate appropriate faecal microbiota transplantation (FMT) capacity is crucial for both health care providers and policymakers striving to enhance patient care for those with...
A comprehensive understanding of how to develop and cultivate appropriate faecal microbiota transplantation (FMT) capacity is crucial for both health care providers and policymakers striving to enhance patient care for those with...
A comprehensive understanding of...
10/02/2023
First Report Managed Care
News
Study Finds Substantial Gaps in Nurse Understanding of CDI Prevention
09/27/2023
A study published in the journal Antibiotics found that less than one-third of the participating nurses knew that using soap and water is the recommended handwashing method to prevent the spread of CDI effectively.
A study published in the journal Antibiotics found that less than one-third of the participating nurses knew that using soap and water is the recommended handwashing method to prevent the spread of CDI effectively.
A study published in the journal...
09/27/2023
First Report Managed Care
News
Transmission of C difficile Between People and Pets Appears Rare
09/26/2023
“It is unclear why pets appear to only infrequently acquire C difficile from their owners,” researchers wrote. “It may be that the canine gut microbiota is better able to provide colonization resistance against C difficile, even when in an...
“It is unclear why pets appear to only infrequently acquire C difficile from their owners,” researchers wrote. “It may be that the canine gut microbiota is better able to provide colonization resistance against C difficile, even when in an...
“It is unclear why pets appear...
09/26/2023
First Report Managed Care

Newsfeed

News
Fecal Microbiota Transplant for Patients With IBD and rCDI: Safety and Efficacy
03/28/2024

Emry Lloyd

Emry Lloyd
Patients with recurrent Clostridioides difficile infection have shown significant results when administered a fecal microbiota transplant. This study evaluated the safety and efficacy of using a fecal microbiota transplant for patients with...
Patients with recurrent Clostridioides difficile infection have shown significant results when administered a fecal microbiota transplant. This study evaluated the safety and efficacy of using a fecal microbiota transplant for patients with...
Patients with recurrent...
03/28/2024
First Report Managed Care
News
Two-Step Testing Linked With Lower Rate of CDI Treatment in Colonized Patients
03/14/2024
Switching to two-step algorithm testing for Clostridioides difficile infection correlated with lower rates of treatment, helping to differentiate colonization from active infection, according to a study published in Clinical Microbiology and...
Switching to two-step algorithm testing for Clostridioides difficile infection correlated with lower rates of treatment, helping to differentiate colonization from active infection, according to a study published in Clinical Microbiology and...
Switching to two-step algorithm...
03/14/2024
First Report Managed Care
News
HexSDF and HexRK are Required for Clostridioides difficile Synthesis, Which Impacts Resistance to Daptomycin and Bacitracin
11/15/2023
“C difficile is a major cause of hospital-acquired diarrhea and represents an urgent concern due to the prevalence of antibiotic resistance and the rate of recurrent infections,” wrote Anthony Pannullo, Department of Microbiology and...
“C difficile is a major cause of hospital-acquired diarrhea and represents an urgent concern due to the prevalence of antibiotic resistance and the rate of recurrent infections,” wrote Anthony Pannullo, Department of Microbiology and...
“C difficile is a major cause of...
11/15/2023
First Report Managed Care
News
Comprehensive C difficile Infection Management Approach
10/17/2023
“Clinical treatment and management need to be multifaceted and consider not just pharmaceutical intervention but a holistic approach to the patient’s experience both during and after CDI, acknowledging the potential psychological and social...
“Clinical treatment and management need to be multifaceted and consider not just pharmaceutical intervention but a holistic approach to the patient’s experience both during and after CDI, acknowledging the potential psychological and social...
“Clinical treatment and...
10/17/2023
First Report Managed Care
News
Navigating CDI Prevention Implementation: Frontline Insights from VA Health Care Facilities
10/11/2023
This research examines the key factors influencing Clostridioides difficile infection (CDI) prevention practices, highlighting the role of organizational commitment, communication, standardization, and the limitations of role hierarchies...
This research examines the key factors influencing Clostridioides difficile infection (CDI) prevention practices, highlighting the role of organizational commitment, communication, standardization, and the limitations of role hierarchies...
This research examines the key...
10/11/2023
First Report Managed Care
News
Study Identifies Challenges and Improvement Opportunities Relating to Faecal Microbiota Transplantation for C difficile Infections
10/02/2023
A comprehensive understanding of how to develop and cultivate appropriate faecal microbiota transplantation (FMT) capacity is crucial for both health care providers and policymakers striving to enhance patient care for those with...
A comprehensive understanding of how to develop and cultivate appropriate faecal microbiota transplantation (FMT) capacity is crucial for both health care providers and policymakers striving to enhance patient care for those with...
A comprehensive understanding of...
10/02/2023
First Report Managed Care
News
Study Finds Substantial Gaps in Nurse Understanding of CDI Prevention
09/27/2023
A study published in the journal Antibiotics found that less than one-third of the participating nurses knew that using soap and water is the recommended handwashing method to prevent the spread of CDI effectively.
A study published in the journal Antibiotics found that less than one-third of the participating nurses knew that using soap and water is the recommended handwashing method to prevent the spread of CDI effectively.
A study published in the journal...
09/27/2023
First Report Managed Care
News
Transmission of C difficile Between People and Pets Appears Rare
09/26/2023
“It is unclear why pets appear to only infrequently acquire C difficile from their owners,” researchers wrote. “It may be that the canine gut microbiota is better able to provide colonization resistance against C difficile, even when in an...
“It is unclear why pets appear to only infrequently acquire C difficile from their owners,” researchers wrote. “It may be that the canine gut microbiota is better able to provide colonization resistance against C difficile, even when in an...
“It is unclear why pets appear...
09/26/2023
First Report Managed Care
News
Addressing Multiple Negatives During Clostridioides difficile Testing
09/20/2023
Insights are shared from a case report of a patient with multiple negative tests for Clostridioides difficile infection, despite presenting with severe colitis, highlighting the challenges in diagnosing and treating C difficile infections.
Insights are shared from a case report of a patient with multiple negative tests for Clostridioides difficile infection, despite presenting with severe colitis, highlighting the challenges in diagnosing and treating C difficile infections.
Insights are shared from a case...
09/20/2023
First Report Managed Care
News
CDI Associated With Worse Outcomes After Certain Surgical Procedures
09/15/2023
Clostridioides difficile infection (CDI) after surgery is differentially associated with hospital length of stay, costs, readmissions, and mortality across specific procedures in US patients, according to a study published in the journal...
Clostridioides difficile infection (CDI) after surgery is differentially associated with hospital length of stay, costs, readmissions, and mortality across specific procedures in US patients, according to a study published in the journal...
Clostridioides difficile...
09/15/2023
First Report Managed Care
News
Using Deep Learning to Measure MS-Specific Brain Damage Beyond Aging
11/11/2024
A new study published in Neurology aimed to differentiate age-related brain changes from multiple sclerosis (MS)-specific neurodegeneration using MRI.
A new study published in Neurology aimed to differentiate age-related brain changes from multiple sclerosis (MS)-specific neurodegeneration using MRI.
A new study published in...
11/11/2024
First Report Managed Care
News
Adverse Event Data Suggest Selective β1-blockers Pose Asthma Risk
11/11/2024
The risks of asthma and asthma-like adverse events appear to be higher with selective β1-blockers than with nonselective blockers and α- and β-blockers.
The risks of asthma and asthma-like adverse events appear to be higher with selective β1-blockers than with nonselective blockers and α- and β-blockers.
The risks of asthma and...
11/11/2024
First Report Managed Care
News
RNAi Therapies Offer New Hope for Patients With Hereditary Transthyretin Amyloidosis
11/08/2024
RNA interference (RNAi)-based treatments for hereditary transthyretin amyloidosis (ATTR) have shown remarkable promise, offering new hope for patients with this rare but devastating genetic disorder.
RNA interference (RNAi)-based treatments for hereditary transthyretin amyloidosis (ATTR) have shown remarkable promise, offering new hope for patients with this rare but devastating genetic disorder.
RNA interference (RNAi)-based...
11/08/2024
First Report Managed Care
News
Revolutionary Single-Dose Gene Therapy Offers New Hope for Adults with Hemophilia B
11/08/2024
A groundbreaking gene therapy for hemophilia B has shown remarkable success in reducing bleeding episodes and improving the quality of life for adult patients, according to a recent international phase III clinical trial.
A groundbreaking gene therapy for hemophilia B has shown remarkable success in reducing bleeding episodes and improving the quality of life for adult patients, according to a recent international phase III clinical trial.
A groundbreaking gene therapy...
11/08/2024
First Report Managed Care
News
Real-World Evidence Supports Efficacy and Safety of Selexipag in Patients With Pulmonary Arterial Hypertension
11/07/2024
Real-world data shows selexipag effectively improves functional class and risk category outcomes in patients with pulmonary arterial hypertension, regardless of maintenance dose.
Real-world data shows selexipag effectively improves functional class and risk category outcomes in patients with pulmonary arterial hypertension, regardless of maintenance dose.
Real-world data shows selexipag...
11/07/2024
First Report Managed Care
News
Clinical Predictors of One-Year Seizure Freedom After SLAH
11/06/2024
A study published in Annals of Clinical and Translational Neurology aimed to predict 1-year seizure freedom for patients undergoing stereotactic laser amygdalohippocampotomy (SLAH) for mesial temporal lobe epilepsy (MTLE) using a set of...
A study published in Annals of Clinical and Translational Neurology aimed to predict 1-year seizure freedom for patients undergoing stereotactic laser amygdalohippocampotomy (SLAH) for mesial temporal lobe epilepsy (MTLE) using a set of...
A study published in Annals of...
11/06/2024
First Report Managed Care
News
Efficacy and Outcomes of Neoadjuvant Immunotherapy in Lung Cancer
11/05/2024
A meta-analysis of 43 studies suggests that neoadjuvant chemoimmunotherapy may benefit patients with resectable NSCLC and low tumor PD-L1 levels for event-free survival, showing superior outcomes compared to neoadjuvant chemotherapy.
A meta-analysis of 43 studies suggests that neoadjuvant chemoimmunotherapy may benefit patients with resectable NSCLC and low tumor PD-L1 levels for event-free survival, showing superior outcomes compared to neoadjuvant chemotherapy.
A meta-analysis of 43 studies...
11/05/2024
First Report Managed Care
News
FDA Grants Accelerated Approval for Asciminib as First-Line Treatment in Ph+CML-CP
11/01/2024
Novartis received accelerated approval by the US Food and Drug Administration (FDA) for asciminib, a medication for adult patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase (Ph+CML-CP).
Novartis received accelerated approval by the US Food and Drug Administration (FDA) for asciminib, a medication for adult patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase (Ph+CML-CP).
Novartis received accelerated...
11/01/2024
First Report Managed Care
News
HHS Faces Legal Action From 10 Hospitals Over 2023 Medicare Advantage Rule and Reimbursement Calculations
10/30/2024
Ten hospitals sued the US Department of Health and Human Services (HHS), claiming that they were underpaid Medicare reimbursements for serving low-income patients.
Ten hospitals sued the US Department of Health and Human Services (HHS), claiming that they were underpaid Medicare reimbursements for serving low-income patients.
Ten hospitals sued the US...
10/30/2024
First Report Managed Care
News
Impact of Immune Checkpoint Inhibitors on Multiple Sclerosis Treatment Outcomes
10/29/2024
Relapses and progression of multiple sclerosis were rare in patients treated with immune checkpoint inhibitors, according to a study presented at the American Academy of Neurology 2024 Annual Meeting.
Relapses and progression of multiple sclerosis were rare in patients treated with immune checkpoint inhibitors, according to a study presented at the American Academy of Neurology 2024 Annual Meeting.
Relapses and progression of...
10/29/2024
First Report Managed Care

Insights

alpesh amin
Podcasts
How Does CDI Impact Health Care Utilization, Costs in Older Patients?
10/23/2023
Alpesh Amin, MD, MBA , professor and chair, University of California, discusses the results of a recent study, and explains why better treatments to reduce primary C difficile infection and recurrences in older adults can lower the mortality...
Alpesh Amin, MD, MBA , professor and chair, University of California, discusses the results of a recent study, and explains why better treatments to reduce primary C difficile infection and recurrences in older adults can lower the mortality...
Alpesh Amin, MD, MBA , professor...
10/23/2023
First Report Managed Care
gil melmed md gastrolenterologst
Podcasts
Understanding the Indirect, Direct Costs Linked With Recurrent Clostridioides difficile
09/23/2021
According to Gil Melmed, MD, gastroenterologist, recurrent CDI is multifactorial, and when estimating the burden of this condition, both direct and indirect costs should be considered.
According to Gil Melmed, MD, gastroenterologist, recurrent CDI is multifactorial, and when estimating the burden of this condition, both direct and indirect costs should be considered.
According to Gil Melmed, MD,...
09/23/2021
First Report Managed Care
Gil Melmed, MD
Podcasts
Costs, Utilization Linked With Recurrent Clostridioides difficile Infection
06/30/2021
Gil Melmed, MD, gastroenterologist, discusses recurrence rates among patients with Clostridioides difficile infection, and breaks down the treatment challenges, high costs, and higher health care utilization this patient population often...
Gil Melmed, MD, gastroenterologist, discusses recurrence rates among patients with Clostridioides difficile infection, and breaks down the treatment challenges, high costs, and higher health care utilization this patient population often...
Gil Melmed, MD,...
06/30/2021
First Report Managed Care
Headshot of Dr Gil Melmed on a blue background underneath the PopHealth Perspectives logo.
Podcasts
Bringing Awareness to Clostridioides difficile and Reviewing the Typical Treatment Regimen
06/01/2021
In an effort to bring more awareness to Clostridioides difficile, Gil Melmed, MD, gastroenterologist, Cedars Sinai, Los Angeles, breaks down the typical treatment regimen for this patient population, reviews treatment guidelines, and...
In an effort to bring more awareness to Clostridioides difficile, Gil Melmed, MD, gastroenterologist, Cedars Sinai, Los Angeles, breaks down the typical treatment regimen for this patient population, reviews treatment guidelines, and...
In an effort to bring more...
06/01/2021
First Report Managed Care
Videos
Bridging the Gaps in Prior Authorization: Challenges, Solutions, and Collaboration for Better Patient Care
11/13/2024
David Sand, MD, MBA, chief medical officer at ZeOmega, discusses the challenges of prior authorization, emphasizing the need for transparency, evidence-based standards, collaboration between payers and providers, and the potential for...
David Sand, MD, MBA, chief medical officer at ZeOmega, discusses the challenges of prior authorization, emphasizing the need for transparency, evidence-based standards, collaboration between payers and providers, and the potential for...
David Sand, MD, MBA, chief...
11/13/2024
First Report Managed Care
Jason Oswald Headshot
Commentary
The Impact of AI on Health Carrier Underwriting: Insights From Industry Experts
11/08/2024
"As AI continues to evolve, its integration into group health underwriting offers carriers new opportunities to enhance decision-making, streamline operations, and improve overall plan performance," said Jason Oswald, Director of Solution...
"As AI continues to evolve, its integration into group health underwriting offers carriers new opportunities to enhance decision-making, streamline operations, and improve overall plan performance," said Jason Oswald, Director of Solution...
"As AI continues to evolve, its...
11/08/2024
First Report Managed Care
Hawley Headshot
Commentary
Beyond Medical Cost Savings: Optimizing Payment Integrity Value
10/31/2024
Health plan leaders increasingly recognize the value of utilizing technology as a counteroffensive against high medical loss ratios, which are now close to 90% in the large group market. As the industry is poised to face the same pressures in...
Health plan leaders increasingly recognize the value of utilizing technology as a counteroffensive against high medical loss ratios, which are now close to 90% in the large group market. As the industry is poised to face the same pressures in...
Health plan leaders increasingly...
10/31/2024
First Report Managed Care
Richard Lipton, MD
Videos
The Evolving Role of CGRP-targeting Therapies in Migraine Prevention
10/31/2024
Richard Lipton, MD, provides insights on the American Headache Society’s position statement update on calcitonin gene-related peptide (CGRP)-targeting therapies as a first-line option for the prevention of migraine.
Richard Lipton, MD, provides insights on the American Headache Society’s position statement update on calcitonin gene-related peptide (CGRP)-targeting therapies as a first-line option for the prevention of migraine.
Richard Lipton, MD, provides...
10/31/2024
First Report Managed Care
Trushar Dungarani, MD
Interview
The Role of High-Quality Data in Population Health Initiatives
10/24/2024
In this interview, Trushar Dungarani, DO, SFHM, discusses the importance of high-quality, accessible patient data for clinicians to enhance care delivery, address social determinants of health, and drive effective population health...
In this interview, Trushar Dungarani, DO, SFHM, discusses the importance of high-quality, accessible patient data for clinicians to enhance care delivery, address social determinants of health, and drive effective population health...
In this interview, Trushar...
10/24/2024
First Report Managed Care
SV
Interview
Homecare Insights Survey Offers Glimpse at Caregiver Motivations, Perspectives and Priorities
10/18/2024
Learn about the impact of the 2024 Homecare Insights Survey on caregiver satisfaction and how specialized training, recognition, and technology can enhance patient care and support caregiver well-being.
Learn about the impact of the 2024 Homecare Insights Survey on caregiver satisfaction and how specialized training, recognition, and technology can enhance patient care and support caregiver well-being.
Learn about the impact of the...
10/18/2024
First Report Managed Care
Milo Headshot
Commentary
Transforming Health Care Payer Operations With AI
10/11/2024
Health plans today face mounting pressure to enhance member engagement while improving health outcomes and control rising costs. As health care inflation continues to outpace general inflation across the United States, health plans are...
Health plans today face mounting pressure to enhance member engagement while improving health outcomes and control rising costs. As health care inflation continues to outpace general inflation across the United States, health plans are...
Health plans today face mounting...
10/11/2024
First Report Managed Care
Lynn Carroll
Commentary
How Capitation Contracts Can Benefit Provider and Payer Population Health Initiatives
10/04/2024
In response to the vulnerabilities exposed by the COVID-19 pandemic, provider organizations are increasingly turning to capitation payment models to ensure revenue stability, improve care quality, and manage population health.
In response to the vulnerabilities exposed by the COVID-19 pandemic, provider organizations are increasingly turning to capitation payment models to ensure revenue stability, improve care quality, and manage population health.
In response to the...
10/04/2024
First Report Managed Care
Mike Spellman
Commentary
Unlocking Value in Payment Integrity: A New Paradigm for Health Insurers
10/01/2024
From cost-cutting to value creation, learn how payment integrity is shifting towards a more holistic approach in the health care industry to enhance care quality and stakeholder relationships.
From cost-cutting to value creation, learn how payment integrity is shifting towards a more holistic approach in the health care industry to enhance care quality and stakeholder relationships.
From cost-cutting to value...
10/01/2024
First Report Managed Care
Shannon Smith, RN, BSN
Commentary
Navigating the CY 2025 CMS Physician Fee Schedule Proposals: Strategic Insights for Health Care Leaders
09/30/2024
The Centers for Medicare & Medicaid Services (CMS) has released its calendar year (CY) 2025 physician fee schedule proposals. In this commentary, an expert breaks down the key components and their implications for health care organizations.
The Centers for Medicare & Medicaid Services (CMS) has released its calendar year (CY) 2025 physician fee schedule proposals. In this commentary, an expert breaks down the key components and their implications for health care organizations.
The Centers for Medicare &...
09/30/2024
First Report Managed Care
FRMC Volume 21, Issue 3

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