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Understanding Clostridioides difficile Genetics
03/26/2024

By Emry Lloyd

By Emry Lloyd
Clostridioides difficile is a bacterium that causes gastrointestinal issues in patients. This article describes how physicians can understand Clostridioides difficile and its makeup to determine how to treat or manage infection.
Clostridioides difficile is a bacterium that causes gastrointestinal issues in patients. This article describes how physicians can understand Clostridioides difficile and its makeup to determine how to treat or manage infection.
Clostridioides difficile is a...
03/26/2024
First Report Managed Care
Literature Review
Bladder Cancers: What is Low-Grade Upper Tract Urothelial Carcinoma?
09/16/2022
Edan Stanley
This literature review explores key data related to the epidemiology, clinical presentation, and treatment considerations for patients with low-grade upper tract urothelial carcinoma.
This literature review explores key data related to the epidemiology, clinical presentation, and treatment considerations for patients with low-grade upper tract urothelial carcinoma.
This literature review explores...
09/16/2022
First Report Managed Care
Headshot of Adam Kittai, Ohio State University, on a blue background underneath the PopHealth Perspectives logo.
Podcasts
Second Generation BTK Inhibitors: Reviewing Data on CLL Treatments
06/30/2022
Maria Asimopoulos
Adam Kittai, MD, hematologist and assistant professor of medicine, Ohio State University, shares how second generation BTK inhibitors are changing treatment decisions in chronic lymphocytic leukemia, and adds what payers should keep in mind...
Adam Kittai, MD, hematologist and assistant professor of medicine, Ohio State University, shares how second generation BTK inhibitors are changing treatment decisions in chronic lymphocytic leukemia, and adds what payers should keep in mind...
Adam Kittai, MD, hematologist...
06/30/2022
First Report Managed Care
Headshot of Martin Edelman, Fox Chase Cancer Center, on a blue background underneath the PopHealth Perspectives logo.
Podcasts
Understanding Efficacy, Clinical Use of Lung Cancer Treatment With Phase 3 Data
12/10/2021
Maria Asimopoulos
Martin Edelman, MD, chair, Department of Hematology/Oncology, deputy director of clinical research, Fox Chase Cancer Center, discusses the disease burden of non-small cell lung cancer, as well as the findings from a phase 3 trial that...
Martin Edelman, MD, chair, Department of Hematology/Oncology, deputy director of clinical research, Fox Chase Cancer Center, discusses the disease burden of non-small cell lung cancer, as well as the findings from a phase 3 trial that...
Martin Edelman, MD, chair,...
12/10/2021
First Report Managed Care
Headshot of Saad Usmani, Memorial Sloan Kettering Cancer Center, on a blue background underneath PopHealth Perspectives logo
Podcasts
Financial Burden, Treatment Efficacy and Safety in Multiple Myeloma
12/09/2021
Maria Asimopoulos
Samantha Matthews
Saad Usmani, MD, MBA, FACP, chief of myeloma service, Memorial Sloan Kettering Cancer Center, discusses current challenges in treating multiple myeloma, financial burdens associated with this type of cancer, and where the future of care may...
Saad Usmani, MD, MBA, FACP, chief of myeloma service, Memorial Sloan Kettering Cancer Center, discusses current challenges in treating multiple myeloma, financial burdens associated with this type of cancer, and where the future of care may...
Saad Usmani, MD, MBA, FACP,...
12/09/2021
First Report Managed Care
Ajai Chari, MD, professor of medicine, hematology, and medical oncology, Mount Sinai,
Podcasts
The Costs, Unmet Needs, and Standard of Care Linked With Multiple Myeloma
10/20/2021
Maria Asimopoulos
Julie Gould
Ajai Chari, MD, professor of medicine, hematology, and medical oncology, Mount Sinai, discusses the unmet need in multiple myeloma (MM), challenges specific to treating this disease, why MM is becoming one of the most costly cancers to treat,...
Ajai Chari, MD, professor of medicine, hematology, and medical oncology, Mount Sinai, discusses the unmet need in multiple myeloma (MM), challenges specific to treating this disease, why MM is becoming one of the most costly cancers to treat,...
Ajai Chari, MD, professor of...
10/20/2021
First Report Managed Care
Headshot of Peter Lio, MD, FAAD, on a blue background underneath the PopHealth Perspectives logo.
Podcasts
Addressing Unmet Needs in Patients With Type 2 Inflammatory Conditions
09/28/2021
Edan Stanley
Peter Lio, MD, FAAD, clinical assistant professor of dermatology & pediatrics, Northwestern University Feinberg School of Medicine, and founding director, Chicago Integrative Eczema Center, discusses the common challenges associated with...
Peter Lio, MD, FAAD, clinical assistant professor of dermatology & pediatrics, Northwestern University Feinberg School of Medicine, and founding director, Chicago Integrative Eczema Center, discusses the common challenges associated with...
Peter Lio, MD, FAAD, clinical...
09/28/2021
First Report Managed Care
Literature Review
Examining Dry Eye Disease Flare Treatments
05/28/2021
Edan Stanley
With a newly proposed and easily applicable definition for dry eye disease, researchers believe the condition can be diagnosed with more consistency as well as inform future trials and research. 
With a newly proposed and easily applicable definition for dry eye disease, researchers believe the condition can be diagnosed with more consistency as well as inform future trials and research. 
With a newly proposed and easily...
05/28/2021
First Report Managed Care
Vibegron Proves Effective as Oral Therapy for Patients With Overactive Bladder
First Report
Vibegron Proves Effective as Oral Therapy for Patients With Overactive Bladder
04/12/2021

Edan Stanley

Edan Stanley
While OAB is not associated with high mortality rates, its effects on quality of life and overall burden can be stressful to patients and diagnosis/treatment is often delayed due to patients’ lack of understanding of available treatments.
While OAB is not associated with high mortality rates, its effects on quality of life and overall burden can be stressful to patients and diagnosis/treatment is often delayed due to patients’ lack of understanding of available treatments.
While OAB is not associated with...
04/12/2021
First Report Managed Care
News Connection
Magnetic Seizure Therapy Effective Treatment Option for MDD
11/20/2020
Compared with electroconvulsive therapy, magnetic seizure therapy offered similar antidepressant efficacy but fewer cognitive side effects in patients with major depressive disorder (MDD), according to a study published in the Annals of...
Compared with electroconvulsive therapy, magnetic seizure therapy offered similar antidepressant efficacy but fewer cognitive side effects in patients with major depressive disorder (MDD), according to a study published in the Annals of...
Compared with electroconvulsive...
11/20/2020
First Report Managed Care
Conference Insider
ENIGMA Study: Novel Antibody Appears Safe, Effective for Eosinophilic GI Disorders
11/20/2019
AK002—an anti-SIGLEC8 antibody—may be a safe and effective treatment option in eosinophilic gastritis (EG) and eosinophilic gastroenteritis (EGE), according to results of ENIGMA, a phase 2 clinical trial.
AK002—an anti-SIGLEC8 antibody—may be a safe and effective treatment option in eosinophilic gastritis (EG) and eosinophilic gastroenteritis (EGE), according to results of ENIGMA, a phase 2 clinical trial.
AK002—an anti-SIGLEC8...
11/20/2019
First Report Managed Care

Newsfeed

News
Understanding Clostridioides difficile Genetics
03/26/2024

By Emry Lloyd

By Emry Lloyd
Clostridioides difficile is a bacterium that causes gastrointestinal issues in patients. This article describes how physicians can understand Clostridioides difficile and its makeup to determine how to treat or manage infection.
Clostridioides difficile is a bacterium that causes gastrointestinal issues in patients. This article describes how physicians can understand Clostridioides difficile and its makeup to determine how to treat or manage infection.
Clostridioides difficile is a...
03/26/2024
First Report Managed Care
Literature Review
Examining Dry Eye Disease Flare Treatments
05/28/2021
Edan Stanley
With a newly proposed and easily applicable definition for dry eye disease, researchers believe the condition can be diagnosed with more consistency as well as inform future trials and research. 
With a newly proposed and easily applicable definition for dry eye disease, researchers believe the condition can be diagnosed with more consistency as well as inform future trials and research. 
With a newly proposed and easily...
05/28/2021
First Report Managed Care
Conference Insider
ENIGMA Study: Novel Antibody Appears Safe, Effective for Eosinophilic GI Disorders
11/20/2019
AK002—an anti-SIGLEC8 antibody—may be a safe and effective treatment option in eosinophilic gastritis (EG) and eosinophilic gastroenteritis (EGE), according to results of ENIGMA, a phase 2 clinical trial.
AK002—an anti-SIGLEC8 antibody—may be a safe and effective treatment option in eosinophilic gastritis (EG) and eosinophilic gastroenteritis (EGE), according to results of ENIGMA, a phase 2 clinical trial.
AK002—an anti-SIGLEC8...
11/20/2019
First Report Managed Care
Conference Insider
Budesonide Oral Suspension May Be Effective for Eosinophilic Esophagitis
11/20/2019
Budesonide oral suspension (BOS) appears to be a safe and effective induction therapy for eosinophilic esophagitis (EoE) among adolescents and adults, according to results of a phase 3 clinical trial that were presented at the ACG 2019 Annual...
Budesonide oral suspension (BOS) appears to be a safe and effective induction therapy for eosinophilic esophagitis (EoE) among adolescents and adults, according to results of a phase 3 clinical trial that were presented at the ACG 2019 Annual...
Budesonide oral suspension (BOS)...
11/20/2019
First Report Managed Care
Conference Insider
Immunotherapy Added to Chemotherapy Improves Ovarian Cancer Patients’ Prognosis
05/17/2019
Results from a randomized phase 2 trial presented at the Society for Gynecologic Oncology’s 50th Annual Meeting show that a newly developed immunotherapy treatment combined with standard chemotherapy improve the prognosis for patients with...
Results from a randomized phase 2 trial presented at the Society for Gynecologic Oncology’s 50th Annual Meeting show that a newly developed immunotherapy treatment combined with standard chemotherapy improve the prognosis for patients with...
Results from a randomized phase...
05/17/2019
First Report Managed Care
Conference Insider
Niraparib Shows Promise as Maintenance Therapy for Ovarian Cancer
05/17/2019
According to research presented at the Society for Gynecologic Oncology’s 50th Annual Meeting, patients with recurrent ovarian cancer experienced more time without symptoms or toxicities when taking niraparib as a maintenance therapy. 
According to research presented at the Society for Gynecologic Oncology’s 50th Annual Meeting, patients with recurrent ovarian cancer experienced more time without symptoms or toxicities when taking niraparib as a maintenance therapy. 
According to research presented...
05/17/2019
First Report Managed Care

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Literature Review

Literature Review
Bladder Cancers: What is Low-Grade Upper Tract Urothelial Carcinoma?
09/16/2022
Edan Stanley
This literature review explores key data related to the epidemiology, clinical presentation, and treatment considerations for patients with low-grade upper tract urothelial carcinoma.
This literature review explores key data related to the epidemiology, clinical presentation, and treatment considerations for patients with low-grade upper tract urothelial carcinoma.
This literature review explores...
09/16/2022
First Report Managed Care
Literature Review
Examining Dry Eye Disease Flare Treatments
05/28/2021
Edan Stanley
With a newly proposed and easily applicable definition for dry eye disease, researchers believe the condition can be diagnosed with more consistency as well as inform future trials and research. 
With a newly proposed and easily applicable definition for dry eye disease, researchers believe the condition can be diagnosed with more consistency as well as inform future trials and research. 
With a newly proposed and easily...
05/28/2021
First Report Managed Care
Formulary Frontlines®
CGRP Inhibitors May Offer Significant Benefits for Migraine Patients
10/17/2019

Jeff Craven

Jeff Craven
With the advent of calcitonin gene-related peptide (CGRP) inhibitors, which are either monoclonal antibodies or CGRP receptor agonists that block CGRP proteins in the head and neck, another treatment option has emerged for patients where...
With the advent of calcitonin gene-related peptide (CGRP) inhibitors, which are either monoclonal antibodies or CGRP receptor agonists that block CGRP proteins in the head and neck, another treatment option has emerged for patients where...
With the advent of calcitonin...
10/17/2019
First Report Managed Care
Formulary Frontlines®
Innovations in Managing Hemophilia
08/26/2019

Eileen Koutnik-Fotopoulos

Eileen Koutnik-Fotopoulos
Although hemophilia is designated an orphan disease by the FDA because it affects fewer than 200,000 people in the United States, it imposes a significant financial and burden on patients, caregivers, and society.
Although hemophilia is designated an orphan disease by the FDA because it affects fewer than 200,000 people in the United States, it imposes a significant financial and burden on patients, caregivers, and society.
Although hemophilia is...
08/26/2019
First Report Managed Care
Literature Review
Promising Outcomes for SER-109: A New Approach to Managing Recurrent CDI
10/23/2023

Danielle Sposato

Danielle Sposato
Not only does SER-109 effectively treat CDI, but results show that it can even reduce recurrence. A major benefit when it comes to associated health care costs for patients.
Not only does SER-109 effectively treat CDI, but results show that it can even reduce recurrence. A major benefit when it comes to associated health care costs for patients.
Not only does SER-109...
10/23/2023
First Report Managed Care
Literature Review
Comparing IL-6 Inhibitors and Glucocorticoids in Treating PMR: SAPHYR Trial Results
10/16/2023

Danielle Sposato

Danielle Sposato
The SAPHYR trial has provided researchers with valuable insights into alternative treatment options for PMR due to its larger patient population. The effectiveness of sarilumab and the achieved rates of remission offer promise for enhancing...
The SAPHYR trial has provided researchers with valuable insights into alternative treatment options for PMR due to its larger patient population. The effectiveness of sarilumab and the achieved rates of remission offer promise for enhancing...
The SAPHYR trial has provided...
10/16/2023
First Report Managed Care
Literature Review
A Look at the Impact, Prevalence of Demodex Blepharitis
12/06/2022
Edan Stanley
This article explores the incidence, prevalence, and management of Demodex Blepharitis.
This article explores the incidence, prevalence, and management of Demodex Blepharitis.
This article explores the...
12/06/2022
First Report Managed Care
Literature Review
Anti-CD38 Monoclonal Antibody for Multiple Myeloma: A Review of Clinical Trials
11/29/2022
Maria Asimopoulos
Several ongoing and upcoming clinical trials are testing the efficacy and safety of a monoclonal antibody in combination with other therapies for multiple myeloma.
Several ongoing and upcoming clinical trials are testing the efficacy and safety of a monoclonal antibody in combination with other therapies for multiple myeloma.
Several ongoing and upcoming...
11/29/2022
First Report Managed Care
Literature Review
Isatuximab Demonstrates Significant PFS Among Patients With Multiple Myeloma
09/23/2022
Edan Stanley
This literature review explores the latest progression-free survival data for a multiple myeloma therapy option.
This literature review explores the latest progression-free survival data for a multiple myeloma therapy option.
This literature review explores...
09/23/2022
First Report Managed Care
Literature Review
Bladder Cancers: What is Low-Grade Upper Tract Urothelial Carcinoma?
09/16/2022
Edan Stanley
This literature review explores key data related to the epidemiology, clinical presentation, and treatment considerations for patients with low-grade upper tract urothelial carcinoma.
This literature review explores key data related to the epidemiology, clinical presentation, and treatment considerations for patients with low-grade upper tract urothelial carcinoma.
This literature review explores...
09/16/2022
First Report Managed Care
Literature Review
Examining 177Lu-PSMA-617 as a Treatment for Metastatic Castration-resistant Prostate Cancer
09/16/2021
Jeff Craven
In this literature review, we explore the data from the phase 3 VISION trial recently presented at the 2021 virtual annual meeting of the American Society of Clinical Oncology and published in the New England Journal of Medicine, examining...
In this literature review, we explore the data from the phase 3 VISION trial recently presented at the 2021 virtual annual meeting of the American Society of Clinical Oncology and published in the New England Journal of Medicine, examining...
In this literature review, we...
09/16/2021
First Report Managed Care
Literature Review
Examining Benefits of Cannabidiol for Patients With Seizures
08/12/2021
Edan Stanley
For the purpose of this literature review, we examine the latest data presented at the American Academy of Neurology’s (AAN) 2021 Virtual Annual Meeting regarding the use of CBD for patients with seizure disorders including TSC.  
For the purpose of this literature review, we examine the latest data presented at the American Academy of Neurology’s (AAN) 2021 Virtual Annual Meeting regarding the use of CBD for patients with seizure disorders including TSC.  
For the purpose of this...
08/12/2021
First Report Managed Care
Literature Review
Examining Dry Eye Disease Flare Treatments
05/28/2021
Edan Stanley
With a newly proposed and easily applicable definition for dry eye disease, researchers believe the condition can be diagnosed with more consistency as well as inform future trials and research. 
With a newly proposed and easily applicable definition for dry eye disease, researchers believe the condition can be diagnosed with more consistency as well as inform future trials and research. 
With a newly proposed and easily...
05/28/2021
First Report Managed Care
Literature Review
Examining Lasmiditan for the Acute Treatment of Migraine Compared With Triptans
02/12/2021

Edan Stanley

Edan Stanley
Per the American Migraine foundation, oral and intranasal triptan therapy has proven consistently effective when used to treat migraine earlier in the attack; however, triptan therapy is not effective for all patients with migraine and cannot...
Per the American Migraine foundation, oral and intranasal triptan therapy has proven consistently effective when used to treat migraine earlier in the attack; however, triptan therapy is not effective for all patients with migraine and cannot...
Per the American Migraine...
02/12/2021
First Report Managed Care

First Report

Weekly Dose of Hemophilia Factor VIII Therapy Delivers Significant Bleed Protection
Pegloticase Benefit Enhanced When Combined With Methotrexate for Patients With Chronic Gout
Zanubrutinib Exhibits Superior Overall Response Rate for Adult Patients With Chronic Lymphocytic Leukemia
Addition of Daratumumab to a Treatment Plan for Transplant Ineligible Patients With Multiple Myeloma Proves Beneficial
Atezolizumab Demonstrates Positive Disease-free Survival Benefit Among Patients With NSCLC
Dupilumab Reduces Type 2 Inflammation, May Offer Clinical Benefits for Multiple Comorbid Diseases
Vibegron Proves Effective as Oral Therapy for Patients With Overactive Bladder
Vibegron Proves Effective as Oral Therapy for Patients With Overactive Bladder
First Report
Vibegron Proves Effective as Oral Therapy for Patients With Overactive Bladder
04/12/2021

Edan Stanley

Edan Stanley
While OAB is not associated with high mortality rates, its effects on quality of life and overall burden can be stressful to patients and diagnosis/treatment is often delayed due to patients’ lack of understanding of available treatments.
While OAB is not associated with high mortality rates, its effects on quality of life and overall burden can be stressful to patients and diagnosis/treatment is often delayed due to patients’ lack of understanding of available treatments.
While OAB is not associated with...
04/12/2021
First Report Managed Care
Weekly Dose of Hemophilia Factor VIII Therapy Delivers Significant Bleed Protection
Pegloticase Benefit Enhanced When Combined With Methotrexate for Patients With Chronic Gout
HCRU Burden of Chronic vs Episodic Migraine and Effect of Early vs Late Nonoral Triptan Use
Zanubrutinib Exhibits Superior Overall Response Rate for Adult Patients With Chronic Lymphocytic Leukemia
Access to Acute Treatments for Migraine Can Reduce Costs for Employers, Health Care System
Addition of Daratumumab to a Treatment Plan for Transplant Ineligible Patients With Multiple Myeloma Proves Beneficial
Atezolizumab Demonstrates Positive Disease-free Survival Benefit Among Patients With NSCLC
Data Supports Progression-Free Survival, Overall Survival for Long-Term CLL/SLL Treatment
ICER Report Ranks Value, Clinical Effectiveness of Dupilumab and Other AD Treatments
Dupilumab Reduces Type 2 Inflammation, May Offer Clinical Benefits for Multiple Comorbid Diseases

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June 2024
Volume 21
Issue 2
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Neither lipid levels nor statin use appears to affect the incidence of proliferative diabetic retinopathy and macular edema, according to a new study.
Neither lipid levels nor statin use appears to affect the incidence of proliferative diabetic retinopathy and macular edema, according to a new study.
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Delve into the rising demand for anti-obesity medications, the complexities of obesity management, and the importance of personalized approaches in improving cardiometabolic health in this insightful interview.
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