venous leg ulcers

A comparative effectiveness research study of a bilayered living cellular construct and a cryopreserved cadaveric skin allograft for use in venous leg ulcers

OBJECTIVES: Using real-world data (RWD) we conducted a comparative effectiveness analysis to study the heal rates of venous leg ulcers (VLUs) that were treated with either a bilayered liv...

08/19/2021

Using Synergy to Address Bioburden During Wound Bed Preparation: A Case Series

Clinical Problem: Routine sharp debridement has been an accepted modality to reduce bioburden1 but scope of practice barriers and site of care limit frequency. Recent evidence suggests no...

08/19/2021

A scientific review of the chemistry of wound healing and hypochlorous acid, why purity of the molecule in a wound cleansing solution matters and why hypochlorite is no longer a must use ingredient.

Objective: Chlorinated species such as molecular chlorine, hypochlorous acid, and sodium hypochlorite all have antimicrobial properties, yet these differ in the cellular response they eli...

11/23/2020

Review

Clinical and Economic Impact of a Two-layer Compression System for the Treatment of Venous Leg Ulcers: A Systematic Review

01/07/2020

Edward A. Goka

Edith Poku

Praveen Thokala

Anthea Sutton

This study evaluates the clinical and cost effectiveness of a 2-layer compression system (2LBA; 3M Coban Two-Layer Compression System; 3M, St Paul, MN) compared with other 2-layer (2LB) and 4-layer (4LB) compression systems in patients with...

This study evaluates the...

01/07/2020

Wounds

The Utilization of a Next-Generation Decellularized Dermal Allograft to Facilitate Closure of a Complex Venous Leg Ulcer

Introduction: The number of individuals with venous leg ulcers (VLU) in the United States continues with up to 5% of the population over 65 years of age and 1.5% of the general population...

11/26/2019

Peripheral Calibrated Gradient Compression Pump for Treatment of Chronic Venous Leg Ulcers

Introduction: Venous leg ulcers (VLUs) can be a difficult to manage wound population, as the underlying vascular compromise can lead to continued peripheral edema and excessive drainage, ...

11/26/2019

Use of an Innovative Silver Impregnated Active Fluid Management Dressing in Heavily Exudating Venous Leg Wounds: An Expanded Case Series

Introduction: Venous leg ulcers (VLUs) are notoriously heavily draining and slough-covered wounds. During the inflammatory response, blood vessel walls dilate and become more porous, allo...

11/05/2019

Use of a Novel Combination Dressing in the Management of Venous Leg Wounds

Background: Venous leg ulcers are notoriously heavily draining and slough-covered wounds making them a challenge to treat. Wound exudate is produced as a normal part of the healing p...

02/09/2019

Current Research

Optimizing Skin Grafting Using Hair-derived Skin Grafts: The Healing Potential of Hair Follicle Pluripotent Stem Cells

03/29/2016

Joshua D. Fox

Katherine L. Baquerizo-Nole

Freya Van Driessche

Elizabeth Yim

Bernard Nusbaum

Francisco Jimenez

Robert S. Kirsner

A man in his 60s with recurrent venous leg ulcers (VLUs) presented with an 18-month history of a VLU on his medial left leg measuring 59.3 cm2. He had been treated with multi-component compression bandages without significant decrease in...

A man in his 60s with recurrent...

03/29/2016

Wounds

Original Research

The Effect of Combined Ultrasound and Electric Field Stimulation on Wound Healing in Chronic Ulcerations

07/10/2015

Ram Avrahami

Jonathan Rosenblum

Michael Gazes

Sean Rosenblum

Leib Litman

Ultrasound and electric stimulation are known therapies for the treatment of chronic ulcerations. Combined modulated ultrasound and electric field stimulation (CUSEFS) have never been studied as a single modality. The authors evaluate the...

Ultrasound and electric...

07/10/2015

Wounds