venous leg ulcers

Using Synergy to Address Bioburden During Wound Bed Preparation: A Case Series

Clinical Problem: Routine sharp debridement has been an accepted modality to reduce bioburden1 but scope of practice barriers and site of care limit frequency. Recent evidence suggests no...

Catherine T. Milne , APRN, MSN, CWOCN-AP, ANP, ACNS-BC;

08/19/2021

A comparative effectiveness research study of a bilayered living cellular construct and a cryopreserved cadaveric skin allograft for use in venous leg ulcers

OBJECTIVES: Using real-world data (RWD) we conducted a comparative effectiveness analysis to study the heal rates of venous leg ulcers (VLUs) that were treated with either a bilayered liv...

Michael Leon Sabolinski , MD;

Oscar M. Alvarez , PhD;

08/19/2021

A scientific review of the chemistry of wound healing and hypochlorous acid, why purity of the molecule in a wound cleansing solution matters and why hypochlorite is no longer a must use ingredient.

Objective: Chlorinated species such as molecular chlorine, hypochlorous acid, and sodium hypochlorite all have antimicrobial properties, yet these differ in the cellular response they eli...

Jelena Marjanovic ;

Cheyanne R. Head ;

Irena Pastar , PhD;

Ivan Jozic ;

Marjana Tomic-Canic , PhD;

Rivka Stone ;

Gregory S. Schultz , PhD;

11/23/2020

Review

Clinical and Economic Impact of a Two-layer Compression System for the Treatment of Venous Leg Ulcers: A Systematic Review

01/07/2020

Edward A. Goka ;

Anthea Sutton ;

Praveen Thokala ;

Edith Poku ;

This study evaluates the clinical and cost effectiveness of a 2-layer compression system (2LBA; 3M Coban Two-Layer Compression System; 3M, St Paul, MN) compared with other 2-layer (2LB) and 4-layer (4LB) compression systems in patients with...

This study evaluates the...

01/07/2020

Wounds

The Utilization of a Next-Generation Decellularized Dermal Allograft to Facilitate Closure of a Complex Venous Leg Ulcer

Introduction: The number of individuals with venous leg ulcers (VLU) in the United States continues with up to 5% of the population over 65 years of age and 1.5% of the general population...

Felipe Ruiz ;

11/26/2019

Peripheral Calibrated Gradient Compression Pump for Treatment of Chronic Venous Leg Ulcers

Introduction: Venous leg ulcers (VLUs) can be a difficult to manage wound population, as the underlying vascular compromise can lead to continued peripheral edema and excessive drainage, ...

Brooke Weiss , PA;

Emily Pesek , BS;

Jani Lee , MD;

John C. Lantis II, MD, FACS;

Munir Patel , MD;

Scott Ellis , MD;

11/26/2019

Use of an Innovative Silver Impregnated Active Fluid Management Dressing in Heavily Exudating Venous Leg Wounds: An Expanded Case Series

Introduction: Venous leg ulcers (VLUs) are notoriously heavily draining and slough-covered wounds. During the inflammatory response, blood vessel walls dilate and become more porous, allo...

Windy E. Cole , DPM, CWSP, FACCWS;

11/05/2019

Use of a Novel Combination Dressing in the Management of Venous Leg Wounds

Background: Venous leg ulcers are notoriously heavily draining and slough-covered wounds making them a challenge to treat. Wound exudate is produced as a normal part of the healing p...

Windy E. Cole , DPM, CWSP, FACCWS;

02/09/2019

Current Research

Optimizing Skin Grafting Using Hair-derived Skin Grafts: The Healing Potential of Hair Follicle Pluripotent Stem Cells

03/29/2016

Bernard Nusbaum ;

Robert S. Kirsner , MD, PhD;

Francisco Jimenez ;

Freya Van Driessche ;

Katherine L. Baquerizo-Nole ;

Elizabeth Yim ;

Joshua D. Fox ;

A man in his 60s with recurrent venous leg ulcers (VLUs) presented with an 18-month history of a VLU on his medial left leg measuring 59.3 cm2. He had been treated with multi-component compression bandages without significant decrease in...

A man in his 60s with recurrent...

03/29/2016

Wounds

Original Research

The Effect of Combined Ultrasound and Electric Field Stimulation on Wound Healing in Chronic Ulcerations

07/10/2015

Jonathan I. Rosenblum , DPM;

Michael I. Gazes , DPM, MPH, FACFAS, FACPM;

Sean Rosenblum ;

Ram Avrahami ;

Leib Litman ;

Ultrasound and electric stimulation are known therapies for the treatment of chronic ulcerations. Combined modulated ultrasound and electric field stimulation (CUSEFS) have never been studied as a single modality. The authors evaluate the...

Ultrasound and electric...

07/10/2015

Wounds