Irena Pastar, PhD

Microclimate Comparison of Five-Layer Foam Dressings

Prophylactic use of five-layer foam dressings to reduce the risk of developing a pressure injury (PI) is a key component of a PI prevention protocol. These dressings mitigate contributing...

Hadar A. Lev-Tov , MD, MAS, MSc;

Natasa Strbo , MD, PhD;

Katelyn Rivas , BA;

Irena Pastar , PhD;

Divya Chopra , BS;

Marjana Tomic-Canic , PhD;

Paola Catanuto , PhD;

Martha Roman , BS ;

Lindsey Siegfried , BS;

05/26/2022

Don’t Stop Me Now: Investigating the Influence of Novel Antimicrobial EPC-373K on Keratinocyte Migration In-Vitro

Introduction: Public health concerns over antibiotic-resistant pathogens has spurred the development of non-traditional antimicrobials. These non-traditional antimicrobials offer advantag...

David Goldsmith , PhD;

Stephen C. Davis , BS, MS;

Irena Pastar , PhD;

Hadar A. Lev-Tov , MD, MAS, MSc;

Carla J. Spina , PhD;

Joel Gil , BS, MS;

Phillip Frost ;

Michael Solis , MBA;

Aurelie Boulzemat , PhD;

Bela Kelety , PhD;

05/26/2022

Comparison of a Copper-based Antimicrobial Burn Dressing and KerraCel-Ag, a Commercial Silver Burn Dressing

Introduction: Reported here is a preliminary study of a cost-effective copper-based antimicrobial hydrogel wound dressing intended for the treatment of burn wounds for military applicatio...

Aaron D. Strickland , PhD;

Rebecca Verpile , BS ;

Jingjing Meng , PhD;

Irena Pastar , PhD;

Jamie Burgess , MS;

Marjana Tomic-Canic , PhD;

Hadar A. Lev-Tov , MD, MAS, MSc;

05/26/2022

Inflammation is Induced by Intracellular MRSA Colonization of Diabetic Foot Ulcers

Background: Persistent wound infection frequently complicates diabetic foot ulcers (DFU) treatment and is a leading cause of amputations. Dramatic increase in community-acquired Methicill...

Robert S. Kirsner , MD, PhD;

Marjana Tomic-Canic , PhD;

Rivka Stone ;

Jamie Burgess , MS;

Hadar A. Lev-Tov , MD, MAS, MSc;

Cheyanne R. Head ;

Irena Pastar , PhD;

Andrew Sawaya ;

Ivan Jozic ;

Natasa Strbo , MD, PhD;

Jelena Marjanovic ;

08/19/2021

A scientific review of the chemistry of wound healing and hypochlorous acid, why purity of the molecule in a wound cleansing solution matters and why hypochlorite is no longer a must use ingredient.

Objective: Chlorinated species such as molecular chlorine, hypochlorous acid, and sodium hypochlorite all have antimicrobial properties, yet these differ in the cellular response they eli...

Jelena Marjanovic ;

Cheyanne R. Head ;

Irena Pastar , PhD;

Ivan Jozic ;

Marjana Tomic-Canic , PhD;

Rivka Stone ;

Gregory S. Schultz , PhD;

11/23/2020

Identification and Characterization of Silver Tolerant Bactria in Venous Leg Ulcers

Venous leg ulcers (VLU) are a significant burden on the healthcare system and patients. Silver based therapies are common practice yet recently reports emerge of silver resistant bacteria...

Hadar A. Lev-Tov , MD, MAS, MSc;

Cheyanne R. Head ;

Irena Pastar , PhD;

11/23/2020

Perforin-2: a New Molecule on the Block That Kills Bacteria Inside Human Cells, But Not In Diabetic Foot Ulcers

Bacterial infection contributes to impediment of wound healing process, however the mechanisms by which this occurs are not fully understood. Bacteria can reside inside of human cells hid...

Robert S. Kirsner , MD, PhD;

Cheyanne R. Head ;

Irena Pastar , PhD;

Lulu L. Wong ;

Marjana Tomic-Canic , PhD;

Andrea Ferreira ;

Andrew Sawaya ;

Laura Romero ;

Natasa Strbo , MD, PhD;

02/09/2019