diabetic foot ulcers

Case Series

Use of a Novel Purified Reconstituted Bilayer Matrix for Treatment of Chronic Diabetic Foot Ulcers: A Retrospective Case Series

01/25/2023

Adam L. Isaac

Michael Tritto

This retrospective review examined 10 chronic diabetic foot ulcer patients treated with novel purified reconstituted bilayer matrix to assess safety and efficiency with a primary endpoint of wound closure at 12 weeks.

This retrospective review...

01/25/2023

Wounds

A comparative effectiveness research study of a native Type I collagen matrix plus polyhexamethylene biguanide antimicrobial and a cryopreserved cadaveric skin allograft for use in diabetic foot ulcers – a non-inferiority analysis

OBJECTIVE: Real-world effectiveness was evaluated in a large patient population at 246 US treatment facilities comparing a purified native cross-linked extracellular matrix plus polyhexam...

08/19/2021

12-week RCT Evaluating Impact of Routine Fluorescence Imaging of Bacteria on Diabetic foot ulcer healing rates

Introduction: Bacterial burden >104 CFU/g is known to delay healing1,2 and is challenging to detect in diabetic foot ulcers where co-morbidiites including neuropathy can mask clinical...

08/19/2021

Comparing the Composition of Cutaneous Microbiota on the Plantar Surface and Interdigital Spaces of the Diabetic and Non-diabetic Foot

Introduction: The skin is an ecosystem that contains a wide variety of micro-organisms. Alterations in the cutaneous microbiome not only disrupt the host-microbe relationship but can perm...

08/19/2021

OBL Corner

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Peripheral Arterial Disease

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Initial Experience Using a Broad Spectrum Antimicrobial Wound Gel to Disrupt Biofilm Integrity and Bacterial Recolonization in Diabetic Foot Ulcers

A broad spectrum antimicrobial wound gel* with a polyethylene glycol-based hydrogel, a high osmolarity solution and a surfactant has been developed to bring EPS into solution and lyse enc...

01/28/2021

Use of Oxidized Regenerated Cellulose (ORC)/Collagen/Silver-ORC Dressings in Diabetic Foot Ulcers: A Small Case Series

Development of diabetic foot ulcers (DFUs) has an estimated 15% lifetime incidence rate in diabetic patients.1 Patients with DFUs have increased risk of infection, amputation, or mortalit...

11/23/2020

Digital Transformation of a Multidisciplinary Diabetes Foot Service in South Derbyshire, UK

Abstract Body: South Derbyshire has a well-established, integrated multidisciplinary diabetes foot team (MDFT) service. The service was facing increasing pressures from growing demand and...

11/23/2020

Diabetic Foot Ulcers

Pearls for Best Practice in Treating and Offloading DFUs

09/03/2020

James McGuire, DPM, PT, LPed, FAPWHc

Barbara Aung, DPM, CWS, FAPWHc

Offloading is a large piece of the puzzle for treating diabetic foot ulcers, with non-removable devices providing the best pressure relief. These authors discuss effective offloading devices, addressing challenges with patient adherence to...

Offloading is a large piece of...

09/03/2020

Today's Wound Clinic