Use of Oxidized Regenerated Cellulose (ORC)/Collagen/Silver-ORC Dressings in Diabetic Foot Ulcers: A Small Case Series

Introduction: Development of diabetic foot ulcers (DFUs) has an estimated 15% lifetime incidence rate in diabetic patients.1 Patients with DFUs have increased risk of infection, amputation, or mortality.1

Treatment for DFUs can be complex and often utilizes advanced wound care modalities. One such advanced wound care modality is the oxidized regenerated cellulose (ORC)/collagen/silver-ORC dressing*. This ORC/collagen/silver-ORC dressing helps provide a moist wound environment that promotes granulation tissue formation. The use of ORC/collagen/silver-ORC dressings in 3 patients with diabetic foot wounds is presented.

Methods: Oral or intravenous antibiotics were given as necessary. Each wound underwent sharp debridement, followed by the application of ORC/collagen/silver-ORC dressings. Dressing changes occurred every 2-3 days. Off-loading was recommended for all patients.

Results: Three male patients (age range 61- 73 years) with DFUs (Wagner Grade 1-3) were treated. The most common comorbidities included diabetes, coronary heart disease, peripheral vascular disease, hypertension, and obesity. The average wound age was 220 days (range 180-240 days). Previous treatment included sharp debridement, collagenase ointment, and hydrofiber dressing use. All wounds closed without complications within an average of 87.3 days (range 42-130 days) following ORC/collagen/silver-ORC dressing use.

Conclusions: ORC/collagen/Silver-ORC dressing use in these patients led to full wound closure.