IntroductionChemoradiotherapy (CRT) with surgery is standard for patients (pts) with locally advanced rectal cancer (LARC), and nivolumab (nivo) is active in microsatellite instability-h...
Background In the phase 3, randomized open-label KEYNOTE-177 (NCT02563002) study 1L pembrolizumab versus chemotherapy provided superior progression-free survival (PFS) at second interim a...
Background
Patients with MSI-H/dMMR mCRC treated with chemotherapy have poorer outcomes than patients with microsatellite stable/MMR proficient mCRC. Pembrolizumab monot...