Pascal Meier, MD

Commentary

Defining the Optimal Treatment for Elderly Patients: Lessons from Real-World Data

07/13/2009

The elderly and the very elderly are the most rapidly growing segment of the population in the Western world.1–3 The prevalence of coronary artery disease rises with age, and coronary revascularization is commonly performed in elderly...

The elderly and the very elderly...

07/13/2009

Journal of Invasive Cardiology

Commentary

Drug-Eluting Versus Bare-Metal Stents ‚Äî A One-Horse Race?

01/07/2010

Pascal Meier , MD;

Hitinder S. Gurm , MBBS, MD, FSCAI;

The fact that we are still debating the utility of the bare metal stent (BMS) in 2009 would have seemed unthinkable when the first drug-eluting stent (DES) was approved by the Food and Drug Administration for clinical use in the U.S. in 2003....

The fact that we are still...

01/07/2010

Journal of Invasive Cardiology

Commentary

Anticoagulation during Percutaneous Coronary Intervention in Diabetics ‚Äî Is Simpler Always Better?

02/24/2010

Pascal Meier , MD;

Hitinder S. Gurm , MBBS, MD, FSCAI;

Bivalirudin is theoretically a promising alternative to unfractionated heparin (UFH). It is a direct thrombin inhibitor and has the ability to block circulating and clot-bound thrombin and prevent thrombin-mediated platelet activation.1...

Bivalirudin is theoretically a...

02/24/2010

Journal of Invasive Cardiology

Case Report

The Sword of Damocles: An Illustrative Example of the Life-Saving Effect of the Collateral Circulation

03/01/2011

Pascal Meier , MD;

ABSTRACT: There is an ongoing debate on the effective importance of the collateral network, especially in the current era, where most patients with significant coronary artery disease are revascularized, be it percutaneously or surgically;...

ABSTRACT: There is an ongoing...

03/01/2011

Journal of Invasive Cardiology

Original Contribution

Endothelialization of Sirolimus-Eluting Stents with Slow and Extended Drug Release in the Porcine Overstretch Model

12/01/2008

Daniela Frey , BA;

Michael Billinger , MD;

Pascal Meier , MD;

Olgica Beslac , RN;

Raphael Grossenbacher , RN;

Otto M. Hess , MD, PhD;

ABSTRACT: Background. Vascular healing of intracoronary stents has been shown to be delayed in drug-eluting stents (DES) due to the cytotoxic compounds on the stent surface that prevent stent ingrowth and endothelialization. The lack of...

ABSTRACT: Background. Vascular...

12/01/2008

Journal of Invasive Cardiology

Original Contribution

Endothelial-Cell-Binding Aptamer for Coating of Intracoronary Stents

10/07/2010

Michael Billinger , MD;

Pascal Meier , MD;

Otto M. Hess , MD, PhD;

Yvonne Strahm , BA;

Annina Flueckiger , BA;

Daniel Mettler , DVM;

Susan Weisser , RN;

Thomas Schaffner , MD;

ABSTRACT: Oligonucleotides capturing CD31 endothelial cells (= aptamer) were used for coating of intracoronary stents to improve endothelialization and vascular healing. Methods. Three different coronary stents were implanted in 9 farm-raised...

ABSTRACT: Oligonucleotides...

10/07/2010

Journal of Invasive Cardiology