Nina Bionda, PhD

Original Research

Synergistic Effect and Antibiofilm Activity of a Skin and Wound Cleanser

08/01/2020

In this study, 3 of the components in a wound cleanser are tested to determine synergy in eradicating biofilms of methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa in vitro.

In this study, 3 of the...

08/01/2020

Wounds

Original Research

Efficacy of Wound Cleansers on Wound-Specific Organisms Using In Vitro and Ex Vivo Biofilm Models

10/30/2020

Joseph C. Salamone , PhD;

Nina Bionda , PhD;

Ann Beal Salamone , MA;

Suprena Poleon , BS;

Rebecca Erin McMahon , MBA, PhD;

The results indicate that 1 PHMB-based cleanser was effective in reducing mature P aeruginosa, MRSA, and C albicans biofilms and that sustained antimicrobial presence was necessary to reduce or eliminate these mature biofilms.

The results indicate that 1...

10/30/2020

Wound Management & Prevention

Development of Peptide-Based Wound Dressings for Prevention and Management of Infected Wounds

Reported here is the development of peptide-based wound dressings, a polyurethane foam dressing and a collagen dressing substrate both containing host defense peptides (HDPs)1-2 as active...

Sunil Saini , PhD;

Brandon Johnson , PhD;

Victoria Stefanelli , PhD;

Nina Bionda , PhD;

Nathaniel Remlinger , PhD;

05/26/2022

Determination of the Debridement Effects of an Enzymatic Hydrogel on Deep Dermal Wounds using a Porcine Model

Establishing and maintaining a pathogen-free environment of acute and chronic wounds is vital for optimum healing.1-4 One of the first steps in preventing biofilm consists of debriding th...

Joel Gil , BS, MS;

Nina Bionda , PhD;

Stephen C. Davis , BS, MS;

Mehmet Ozturk , PhD;

Tricia Conti , MS;

Kimberly Jaskula , MS;

Sara Ryan , BS;

Alexander Higa , MA;

Jillian Patterson , BS;

05/26/2022

Digital Image Processing for High Throughput Microbiological Assays: Implementing Customizable Software to Streamline Data Processing

Typical in vitro microbiology assays that produce high volumes of agar plates for colony counting can be overwhelming, time-consuming, and inaccurate when plates are counted manually. To ...

Sophia He ;

Nina Bionda , PhD;

Aaron D. Strickland , PhD;

Alison Moran ;

12/09/2019

Important Considerations for Wound Dressing Development and Testing Using AATCC Test Method 100

Solid phase dressings are a standard for companies developing antimicrobial dressings for the wound care market. Dressings are available in many form factors, including woven and non-wove...

Aaron D. Strickland , PhD;

Alison Moran ;

James Gras ;

Nina Bionda , PhD;

12/09/2019

Ex Vivo Porcine Dermal Model as a Bridge Between in Vitro and in Vivo Screening for Anti-Biofilm Efficacy

Reported here is the development and implementation of an ex vivo porcine dermal model of mature biofilm compatible for evaluation of an array of wound care therapies. The major advantage...

Aaron D. Strickland , PhD;

James Gras ;

Elizabeth J. Bevels , BS ;

Ellen Lantz ;

Nina Bionda , PhD;

12/06/2019

Candida Auris Biofilms in an Ex Vivo Porcine Dermal Model

Candida auris, a drug-resistant yeast, has recently been reported infecting patients in hospitals and nursing homes worldwide. With the increased attention this pathogen has received, and...

Aaron D. Strickland , PhD;

Alison Moran ;

Elizabeth J. Bevels , BS ;

Nina Bionda , PhD;

12/06/2019

In-Vitro Analysis of Simulated Wound Fluid and MMP Transfer from the Periwound Using a Fluid Management Dressing

Background: Precise regulation of wound matrix metalloproteinases (MMPs) promotes optimal wound healing. For chronic wounds, the balance of MMPs is often disrupted, which may stall t...

Nina Bionda , PhD;

Rajib Mondal ;

Aaron D. Strickland , PhD;

Alison Moran ;

Naomi DeVries , BS;

08/19/2019