Fungicidal Effectiveness of Super-Oxidized Solution In Vitro

Dr. Ranjeni Krishnen shares key details from their original research, “Fungicidal Effectiveness of Super-Oxidized Solution In Vitro: Potential Implications for Wound Care.” Additional authors on the article include Sreedharan Muniandy, MBBS. Read the full paper here.
 

Transcript:

Hello, everyone. My name is Ranjeni Krishnen. I'm a Scientific Advisor at Bactiguard. I hold a degree in Industrial Chemistry and hold a PhD in Civil Engineering. Alongside with my co-author, Dr. Sreedharan and with the support of Bactiguard, we had a privilege to conduct research to study the efficacy of super-oxidized solution against fungal infections in chronic wounds. Today, I'm delighted to share some key insights with you.

In our article, we focused on addressing the pressing issue of drug-resistant fungal infections in chronic wound, which is a significant challenge for clinicians. These infections not only delay the wound healing process, but also promotes the biofilm, which further complicates the treatment process. Hence, there is a crucial need for interventions that can control fungal infections without hindering the wound healing process.

The aim of our study was to explore whether super-oxidized solution could serve as a potential solution to this problem. We conducted an individual time-kill test on 6 common fungus species, including Candida albicans, Candida auris, Candida tropicalis, Candida parapsilosis, Sporothrix schenckii, and Trichophyton mentagrophytes.

The results is remarkable. Super-oxidized solution demonstrated a strong fungicidal effect achieving, an impressive 99.999% reduction in all tested fungi within just one minute of exposure. These findings suggest that super-oxidized solution could be a promising tool for preventing and controlling fungal infections in wound care.

The inspiration came from our previous work with super-oxidized solution which have known for its excellent antimicrobial activities against various bacteria. When news of emergency of Candida auris infections in Singapore rise, it immediately caught our attention. We saw an opportunity in exploring the potential of super-oxidized solution to fight against antimicrobial resistance.

We did not encounter any surprising results, but we were pleased with the significant efficacy of the solution against candida species. These results validate the potential of the super-oxidized solution as a promising tool for preventing and controlling fungal infection in the wound care settings.

Looking ahead, we believe there is a great potential for further research in this area: for example, studying the efficacy of super-oxidized solution against fungal biofilm. Most importantly, we should look into translating these amazing results in clinical setting that can benefit millions of people.