Successes of Surgical Applications of a Novel Biologic Fish Skin in the Lower Extremity

A novel fish skin acellular dermal matrix (ADM) has been introduced into the family of biological materials for the treatment of wounds and burns. Most wounds are traditionally full-thickness injuries with typical loss of dermal and epidermal components.

Due to the failure rates of full-thickness injuries to regenerate the dermis, it is imperative to use a biological ADM that has properties and structure consistent with human skin to achieve dermal regeneration. The prospective fish skin acellular dermal matrix contains all the necessary components of the extracellular matrix and dermis and epidermis to repair and regenerate these dermal structures from injury.  

The additional component of omega-3 in the fish skin ADM may contribute to the reduction of acute or chronic inflammation and pain in full-thickness wounds. This composite presentation of surgical wound care patients will demonstrate not only efficacy, but reduction in pain and inflammation as well as acceleration of dermal regeneration. Such surgical application can be done remotely in the private office environment, as well as in outpatient wound treatment centers, without the need for the operating room theater.