A New Model for Predicting Complex Mohs Micrographic Surgery

A model to predict the number of stages needed in Mohs micrographic surgery (MMS) and the need for a complex closure was developed in a recent study published in the Journal of the European Academy of Dermatology and Venereology.

Researchers aimed to identify factors associated with complex MMS and develop a predictor model of the number of stages needed in surgery and the need for a complex closure in a nationwide prospective cohort study of patients with a histologic diagnosis of basal cell carcinoma. 

A model to predict the need for 3 or more stages included tumor dimension, immunosuppression, recurrence, location in risk areas, histologic aggressiveness, and previous surgery. Histologic aggressiveness, evolution time, patient age, maximum tumor dimension, and location were used to predict the need for a complex closure.

“We present a model to predict MMS needing 3 or more stages and a complex closure based on epidemiological and clinical data validated in a large population (with real practice variability) including different centers that could be easily implemented in clinical practice,” explained the study authors.

Reference
Montero-Vilchez T, Garcés JR, Rodríguez-Prieto MA, et al. Development and validation of a model to predict complex Mohs micrographic surgery in clinical practice: REGESMOSH scale. J Eur Acad Dermatol Venereol. Published online March 23, 2023. doi:10.1111/jdv.19056