Effectiveness and Pain Reduction Identified as the Most Important Treatment Attributes in Hidradenitis Suppurativa Management

According to a study published in The Patient, effectiveness and pain reduction are the 2 most important treatment attributes identified by patients in the management of hidradenitis suppurativa.

In a multinational discrete choice experiment, researchers aimed to determine which treatment attributes adult patients with HS in Europe consider the most important in treatment decision-making. Adult patients were given 15 sets of 2 treatment options and asked to choose their preferred treatment. The treatments were characterized by effectiveness, pain reduction, duration of treatment benefit, risk of mild adverse event, risk of serious infection, and mode of administration. Patient preferences were estimated using a random parameter logit model.

A total of 219 patients with hidradenitis suppurativa were included in the study. Of these, 47.9% determined effectiveness to be the most important treatment attribute. Other important treatment attributes included pain reduction (17.3%), annual risk of a mild adverse event (14.4%), annual risk of a serious infection (10.3%), mode of administration (5.3%), and duration of treatment benefit (4.8%). A 75% or 100% reduction in the abscess and inflammatory nodule count was preferred over levels of effectiveness investigated in current clinical trials.

“This study revealed the most important treatment characteristics for patients with hidradenitis suppurativa that can help inform joint patient-physician decision-making in the management of hidradenitis suppurativa,” concluded the study authors.

Reference
Willems D, Hinzpeter EL, Van der Zee HH, et al. Patient preferences in the management of hidradenitis suppurativa: results of a multinational discrete choice experiment in Europe. Patient. Published online ahead of print January 11, 2023. doi:10.1007/s40271-022-00614-7