Chronic Inflammatory Skin Disease Not Associated With Increased Incidence of Venous Thromboembolism

Dermatologist-diagnosed chronic inflammatory skin disease (CISD) does not increase the incidence of venous thromboembolism (VTE).

Researchers examined the incidence rate per 1000 person-years of VTE in patients with CISD and without CISD in a cohort study using commercial insurance claims data from a nationwide US health care database from January 1, 2004, through 2019.

The incidence rate of VTE was .57 in psoriasis, 1.83 in atopic dermatitis, 0.94 in alopecia areata, 0.93 in vitiligo, 1.65 in HS, and 1.53 in CISD overall, compared with 1.76 in patients without a CISD. Incidence rates increased in patients aged 50 years or older and decreased in patients aged 18 to 49 years.

“In this large-scale cohort study, CISDs were not associated with an increased incidence of VTE after controlling for relevant VTE risk factors in a representative dermatology patient population,” concluded the study authors.

Reference
Schneeweiss MC, Kim SC, Wyss R, et al. Incidence of venous thromboembolism in patients with dermatologist-diagnosed chronic inflammatory skin diseases. JAMA Dermatol. Published May 26, 2021. doi:10.1001/jamadermatol.2021.1570