Atopic Dermatitis Associated with Cardiovascular Disease

Patients with atopic dermatitis (AD) and metabolic disorders are at risk for developing cardiovascular disease (CVD) and major cardiovascular events (MACE), according to a study published in Dermatology and Therapy.

Researchers aimed to determine whether CVD and MACE occur at higher incidences and are independent of metabolic disorders in patients with AD in a retrospective study. A large US-based population of patients with AD over the age of 18 years was examined to determine the risk of CVD and MACE.

For patients with AD and no metabolic disorder, the odds ratio (OR) was 1.25 for CVD and 1.22 for MACE. For patients with AD and metabolic disorders, the OR was 1.09 for CVD and 1.14 for MACE. Long-term follow up revealed patients with AD were more likely to develop CVD and MACE compared with patients without AD. Patients with metabolic disorders were at a higher risk.

AD may increase the risk of developing CVD and MACE in adults, regardless of metabolic disorders, concluded the study authors.

Reference

Wu JJ, Amand C, No DJ, et al. The use of real-world data to evaluate the association between atopic dermatitis and cardiovascular disease: a retrospective claims analysis. Dermatol Ther (Heidelb). Published online August 27, 2021. doi:10.1007/s13555-021-00587-9