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Activated Platelet Rich Plasma Improves Alopecia

Lisa Kuhns, PhD

According to a study published in the Aesthetic Surgery Journal, a recent systematic review and meta-analysis of activated platelet rich plasma (A-PRP) showed it to be a promising and safe method for treating alopecia.

Researchers aimed to assess the clinical efficacy and safety of autologous A-PRP injections in patients with alopecia by comparing the safety, limitations, and outcomes of A-PRP use with prior alopecia research outcomes. A systematic review was performed using the search databases PubMed, EMBASE, the Cochrane Database, and Google Scholar. Relevant articles that included all primary clinical studies involving patients that evaluated A-PRP were selected.

A total of 29 articles and 864 patients were involved in the analysis. A-PRP was found to be effective in treating alopecia and improving hair density before and after therapy in 27 studies. The studies also showed that A-PRP improved terminal hair density between treatment and control groups and hair counts after therapy, promoted hair regrowth and folliculogenesis, reduced hair loss, and initiated the hair cycle.

“This is the first systematic review and meta-analysis of A-PRP as a treatment option for alopecia,” wrote the study authors. “A-PRP appears to be a promising and safe method for treating alopecia,” they concluded.

Reference
Morkuzu S, McLennan AL, Kanapathy M, Mosahebi A. Use of activated platelet rich plasma (A-PRP) on alopecia: a systematic review and meta-analyses. Aesthet Surg J. Published online March 21, 2023. doi:10.1093/asj/sjad073