In children with asthma and AD, the number of topical corticosteroid (TCS) preparations used is associated with lower quality of life (QoL) and increased AD severity, according to recent research by Dr Marijie van der Lee, and colleagues.1
The researchers of the study investigated the association of patient characteristics, comorbidities, and impact of AD on children who have both asthma and AD. Included in the study were 140 children with AD who were selected from a larger cohort of children with a reported use of asthma medication. The characteristics of the children that were assessed included, age, sex, and the number and type of atopic comorbidities. Additionally, medication use for AD was defined using the total number of AD prescriptions, the number of different topical AD prescriptions, and the highest potency topical corticosteroid used.
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To assess QoL, researchers used the Children’s Dermatology Life Quality Index (CDLQI), and to measure AD severity, the Self-Assessed Eczema Area and Severity Index (SA-EASI) was used. Further, determinants of AD severity and QoL were evaluated using Spearman rank tests.
The findings showed that the most strongly associated factors resulting in a lower QoL included, characteristics of AD lesions (Spearman Rs = 0.61–0.69, P<0.01), a higher SA-EASI score (Rs = 0.54, P<0.01), and a larger number of different topical AD prescriptions (Rs = 0.38, P<0.01). Additionally, the researchers found that the factors associated with more severe AD included, age (Rs = −0.36, P < 0.01), larger number of different topical corticosteroid preparations used (Rs = 0.27, P < 0.05), and larger number of topical corticosteroid prescriptions (Rs = 0.25, P < 0.05).
Reference:
1. van der Lee M, Arabkhazaeli A, van Erp FC, et al. Atopic dermatitis characteristics and medication-use patterns in school-age children with AD and asthma symptoms [published June 6, 2017]. Clin Exp Dermatol. DOI: 10.1111/ced.13111.
In children with asthma and AD, the number of topical corticosteroid (TCS) preparations used is associated with lower quality of life (QoL) and increased AD severity, according to recent research by Dr Marijie van der Lee, and colleagues.1
The researchers of the study investigated the association of patient characteristics, comorbidities, and impact of AD on children who have both asthma and AD. Included in the study were 140 children with AD who were selected from a larger cohort of children with a reported use of asthma medication. The characteristics of the children that were assessed included, age, sex, and the number and type of atopic comorbidities. Additionally, medication use for AD was defined using the total number of AD prescriptions, the number of different topical AD prescriptions, and the highest potency topical corticosteroid used.
________________________________________________________________________
Related Content
Understanding Itch
Chronic Actinic Dermatitis Differs in Lighter Versus Darker Skin
________________________________________________________________________
To assess QoL, researchers used the Children’s Dermatology Life Quality Index (CDLQI), and to measure AD severity, the Self-Assessed Eczema Area and Severity Index (SA-EASI) was used. Further, determinants of AD severity and QoL were evaluated using Spearman rank tests.
The findings showed that the most strongly associated factors resulting in a lower QoL included, characteristics of AD lesions (Spearman Rs = 0.61–0.69, P<0.01), a higher SA-EASI score (Rs = 0.54, P<0.01), and a larger number of different topical AD prescriptions (Rs = 0.38, P<0.01). Additionally, the researchers found that the factors associated with more severe AD included, age (Rs = −0.36, P < 0.01), larger number of different topical corticosteroid preparations used (Rs = 0.27, P < 0.05), and larger number of topical corticosteroid prescriptions (Rs = 0.25, P < 0.05).
Reference:
1. van der Lee M, Arabkhazaeli A, van Erp FC, et al. Atopic dermatitis characteristics and medication-use patterns in school-age children with AD and asthma symptoms [published June 6, 2017]. Clin Exp Dermatol. DOI: 10.1111/ced.13111.
In children with asthma and AD, the number of topical corticosteroid (TCS) preparations used is associated with lower quality of life (QoL) and increased AD severity, according to recent research by Dr Marijie van der Lee, and colleagues.1
The researchers of the study investigated the association of patient characteristics, comorbidities, and impact of AD on children who have both asthma and AD. Included in the study were 140 children with AD who were selected from a larger cohort of children with a reported use of asthma medication. The characteristics of the children that were assessed included, age, sex, and the number and type of atopic comorbidities. Additionally, medication use for AD was defined using the total number of AD prescriptions, the number of different topical AD prescriptions, and the highest potency topical corticosteroid used.
________________________________________________________________________
Related Content
Understanding Itch
Chronic Actinic Dermatitis Differs in Lighter Versus Darker Skin
________________________________________________________________________
To assess QoL, researchers used the Children’s Dermatology Life Quality Index (CDLQI), and to measure AD severity, the Self-Assessed Eczema Area and Severity Index (SA-EASI) was used. Further, determinants of AD severity and QoL were evaluated using Spearman rank tests.
The findings showed that the most strongly associated factors resulting in a lower QoL included, characteristics of AD lesions (Spearman Rs = 0.61–0.69, P<0.01), a higher SA-EASI score (Rs = 0.54, P<0.01), and a larger number of different topical AD prescriptions (Rs = 0.38, P<0.01). Additionally, the researchers found that the factors associated with more severe AD included, age (Rs = −0.36, P < 0.01), larger number of different topical corticosteroid preparations used (Rs = 0.27, P < 0.05), and larger number of topical corticosteroid prescriptions (Rs = 0.25, P < 0.05).
Reference:
1. van der Lee M, Arabkhazaeli A, van Erp FC, et al. Atopic dermatitis characteristics and medication-use patterns in school-age children with AD and asthma symptoms [published June 6, 2017]. Clin Exp Dermatol. DOI: 10.1111/ced.13111.
