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Psoriasis Severity Increases Mortality Risk

Adults with psoriasis that covers at least 10% of their body surface area have nearly a 2-fold increased risk of mortality than those without psoriasis, according to the results of a recent study.

The researchers used body surface area (BSA), a measurement of the percentage of body surface covered by psoriasis, for their study of 8760 patients with psoriasis and 87,6000 without it. BSA was determined using surveys distributed to the patients’ general practitioners.

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“Other studies that have examined this question, including our own prior research, have looked at patients who were receiving treatment for psoriasis, which is not an objective measurement of severity, making it unclear to whom the prior studies apply,” the researchers explained. “By using BSA, which we can evaluate in a patient’s clinical visit, we can better understand which patients are at highest risk for future medical problems and need preventative care.”          

Over an average follow-up of 4 years, there was an average of 6.39 deaths per 1000 person years in patients with psoriasis that covered more than 10% of their bodies, compared with 3.24 deaths per 1000 person years in those patients without psoriasis. After adjustment for demographic factors, individuals with a BSA of 10% or greater were 1.79 times more likely to die than those without psoriasis.

Further research is required to better define the specific causes of death in patients with psoriasis, the researchers noted.

—Michael Potts

Reference:

Severity of psoriasis linked to increased risk of death [press release]. Penn Medicine News. August 29, 2017. Philadelphia, Pennsylvania. https://www.pennmedicine.org/news/news-releases/2017/august/severity-of-psoriasis-linked-to-increased-risk-of-death.

Adults with psoriasis that covers at least 10% of their body surface area have nearly a 2-fold increased risk of mortality than those without psoriasis, according to the results of a recent study.

The researchers used body surface area (BSA), a measurement of the percentage of body surface covered by psoriasis, for their study of 8760 patients with psoriasis and 87,6000 without it. BSA was determined using surveys distributed to the patients’ general practitioners.

________________________________________________________________________
Related Content
Is This Eruption From Psoriasis Treatment?
Psoriasis May Itch as Intensely as Atopic Dermatitis
________________________________________________________________________

“Other studies that have examined this question, including our own prior research, have looked at patients who were receiving treatment for psoriasis, which is not an objective measurement of severity, making it unclear to whom the prior studies apply,” the researchers explained. “By using BSA, which we can evaluate in a patient’s clinical visit, we can better understand which patients are at highest risk for future medical problems and need preventative care.”          

Over an average follow-up of 4 years, there was an average of 6.39 deaths per 1000 person years in patients with psoriasis that covered more than 10% of their bodies, compared with 3.24 deaths per 1000 person years in those patients without psoriasis. After adjustment for demographic factors, individuals with a BSA of 10% or greater were 1.79 times more likely to die than those without psoriasis.

Further research is required to better define the specific causes of death in patients with psoriasis, the researchers noted.

—Michael Potts

Reference:

Severity of psoriasis linked to increased risk of death [press release]. Penn Medicine News. August 29, 2017. Philadelphia, Pennsylvania. https://www.pennmedicine.org/news/news-releases/2017/august/severity-of-psoriasis-linked-to-increased-risk-of-death.

Adults with psoriasis that covers at least 10% of their body surface area have nearly a 2-fold increased risk of mortality than those without psoriasis, according to the results of a recent study.

The researchers used body surface area (BSA), a measurement of the percentage of body surface covered by psoriasis, for their study of 8760 patients with psoriasis and 87,6000 without it. BSA was determined using surveys distributed to the patients’ general practitioners.

________________________________________________________________________
Related Content
Is This Eruption From Psoriasis Treatment?
Psoriasis May Itch as Intensely as Atopic Dermatitis
________________________________________________________________________

“Other studies that have examined this question, including our own prior research, have looked at patients who were receiving treatment for psoriasis, which is not an objective measurement of severity, making it unclear to whom the prior studies apply,” the researchers explained. “By using BSA, which we can evaluate in a patient’s clinical visit, we can better understand which patients are at highest risk for future medical problems and need preventative care.”          

Over an average follow-up of 4 years, there was an average of 6.39 deaths per 1000 person years in patients with psoriasis that covered more than 10% of their bodies, compared with 3.24 deaths per 1000 person years in those patients without psoriasis. After adjustment for demographic factors, individuals with a BSA of 10% or greater were 1.79 times more likely to die than those without psoriasis.

Further research is required to better define the specific causes of death in patients with psoriasis, the researchers noted.

—Michael Potts

Reference:

Severity of psoriasis linked to increased risk of death [press release]. Penn Medicine News. August 29, 2017. Philadelphia, Pennsylvania. https://www.pennmedicine.org/news/news-releases/2017/august/severity-of-psoriasis-linked-to-increased-risk-of-death.