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How Common Is Squamous Cell Carcinoma in Venous Ulcerations?

Brian McCurdy, Managing Editor

Patients with longstanding venous ulcerations can have a greater chance of squamous cell carcinoma, notes a case study posted presented at the American College of Foot and Ankle Surgeons Scientific Conference.1
 
The case study focused on a 79-year-old man with a longstanding lower extremity venous stasis ulcer. The patient had been receiving treatment for the ulcer but noted pain and the presence of maggots in the ulcer. The poster notes imaging detected an ill-defined lucent lesion in the anterior aspect of the left tibia with overlying soft tissue.
 
A bone biopsy revealed squamous cell carcinoma without a primary source, according to the poster. The patient received radiation but did not respond to it and ultimately had a below-knee amputation. The authors note the importance of a multidisciplinary team and a support system for the patient.
 
Reference
 
1. Qadri A, Wimbley S, Usen N. Squamous cell carcinoma in longstanding venous ulceration. Presented at the American College of Foot and Ankle Surgeons Scientific Conference, Los Angeles, Feb. 9–12, 2023.