Can NIRS Quantify How Much Oxygen Is Reaching a Wound?
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What research problem or question led your team to this research?
Dr. Patel shared that many wound care providers may see cases present week after week with stalled healing, and that there is not always a concrete way to determine what exactly is stopping that progress. Her team became curious if using near infrared spectroscopy (MIMOSA, Mimosa Diagnostics) could provide feedback on the level of oxygen present in a wound after interventions such as hyperbaric oxygen therapy (HBOT).
How did your team set up and conduct this study, and what were your primary findings?
She noted that the team measured oxygen percentage and temperature before and after hyperbaric dives.1 Adding that these patients have already undergone testing to ensure that macrovascular blood flow itself is adequate to carry oxygen to the wound, she said they wanted to quantify how much was actually reaching the target area.
“We found that most of our patients did increase the percent of oxygen in the wound area and some in the periwound area specifically (after HBOT),” she explained.1 “So knowing that and figuring that out, we concluded that the modality (HBOT) is working in the way we intended.”
What else do you hope clinicians will take away from this research?
“Each patient and each wound have special needs to keep in mind,” said Dr. Patel. “So, we need to ensure that each patient and each wound gets what they need to heal.”
When using a treatment modality, she pointed out that any way to determine the impact or effectiveness of that intervention can help guide future decision-making.
“Are they on the trajectory to heal their wound, or not? If not, we may need to go into different areas to find solutions,” she said.
Overall, Dr. Patel advocated for efforts such as that outlined in this poster to obtain actionable data that could inform clinicians about the results of their treatments.
Jeesha Patel, DPM, is a second-year resident at St. Vincent Hospital in Worcester, MA.
Reference
1. Tickner A, Patel J, Kayani R, et al. Advancing hyperbaric oxygen therapy: Insights from mobile multispectral near infrared spectroscopy imaging. Poster presented at SAWC Fall. October 2024. Las Vegas, NV.
