Rapid Refresh

This animation explains the role of BCMA in the life cycle of plasma cells and the effects of overexpression of BCMA on the abnormal survival of these cells.

This animation discusses the role of BCL2 in normal cell function and explains the effects of disruptions in the BCL2 gene on cell signaling.

This animation explains the role of the ALK oncogene in normal cellular functioning and the effect of an abnormal translocation event where ALK fuses to another gene.

This animation explains the role of the 20S proteasome in regulating the cellular life cycle and the effects of disruptions in the ubiquitin proteasome system.

This animation explains the role of the CEACAM5 glycoprotein in the inhibition of cell differentiation and apoptosis, which can promote tumor growth and metastasis.

This animation explains the role of EZH2 in the regulation of cell growth and the effects of EZH2 overexpression.

This animation explains the role of EGFR in the regulation of cell growth and the effects of the overexpression of EGFR.

This animation explains the role of the CD19 antigen in the primary signaling complex on the surface of B-cells and the effect of overexpression of this antigen.

This animation explains the role of Bruton's tyrosine kinase (BTK) in B-cell development and maturation and the effects of aberrant expression of this oncogene.

This animation explains the role of HER2 in the regulation of cell growth and the negative effects of HER2 overexpression.