In this video, Dr Monje discusses recent evidence regarding the neuronal regulation of the pathobiology of brain tumors and potential implications of this evidence. Dr Monje was presented with an award for this talk at the American Neurological Association’s 145th Annual Meeting.

Michelle Monje, MD, PhD, is a practicing neuro-oncologist and an associate professor of neurology and neurological sciences at Stanford University in Stanford, California.

References:

1. Monje M. Neuronal regulation of brain tumor pathobiology. Talk presented at: American Neurological Association 2020 Virtual Meeting; October 4-9, 2020. https://2020.myana.org/program/sessions/microenvironment-control-brain-tumor-pathogenesis
2. Venkatesh HS, Johung TB, Caretti V, et al. Neuronal activity promotes glioma growth through neuroligin-3 secretion. Cell. 2015;161(4):803-816. doi:10.1016/j.cell.2015.04.012
3. Venkatesh HS, Tam LT, Woo PJ, et al. Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma. Nature. 2017;549:533-537. doi:10.1038/nature24014
4. Venkatesh HS, Morishita W, Geraghty AC, et al. Electrical and synaptic integration of glioma into neural circuits. Nature. 2019;573:539-545. doi:10.1038/s41586-019-1563-y