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Alzheimer Disease Topic Center

Recent News and Updates

Deferiprone Accelerates Cognitive Decline in Patients With Early AD
News
01/16/2025
Deferiprone administered twice a day at 15 mg/kg may accelerate cognitive decline in patients with amyloid-confirmed early Alzheimer disease (AD), according to recent results from a randomized controlled trial published in JAMA Neurology.
Deferiprone administered twice a day at 15 mg/kg may accelerate cognitive decline in patients with amyloid-confirmed early Alzheimer disease (AD), according to recent results from a randomized controlled trial published in JAMA Neurology.
Deferiprone administered twice a...
01/16/2025
Neurology
a researcher examines MRI scans
News
01/02/2025
Type 2 diabetes and an abnormal amyloid-β concentration in cerebrospinal fluid were associated with accelerated brain atrophy and an earlier progression to mild cognitive impairment (MCI) in a cohort study.
Type 2 diabetes and an abnormal amyloid-β concentration in cerebrospinal fluid were associated with accelerated brain atrophy and an earlier progression to mild cognitive impairment (MCI) in a cohort study.
Type 2 diabetes and an abnormal...
01/02/2025
Neurology
Semaglutide May Lower Risk of Alzheimer Disease in Patients With Type 2 Diabetes
News
11/05/2024
Patients with type 2 diabetes and obesity prescribed semaglutide had a 40% to 70% lower risk of a first-time Alzheimer disease (AD) diagnosis compared with patients taking other antidiabetic medications, according to a study published in...
Patients with type 2 diabetes and obesity prescribed semaglutide had a 40% to 70% lower risk of a first-time Alzheimer disease (AD) diagnosis compared with patients taking other antidiabetic medications, according to a study published in...
Patients with type 2 diabetes...
11/05/2024
Psych Congress Network
From Psych Congress Network
An elderly woman sits on a couch
News
09/09/2024
Increasing depression symptoms in older adults were associated with early amyloid accumulation in regions responsible for emotional control, and may foretell later Alzheimer Disease (AD) development
Increasing depression symptoms in older adults were associated with early amyloid accumulation in regions responsible for emotional control, and may foretell later Alzheimer Disease (AD) development
Increasing depression symptoms...
09/09/2024
Psych Congress Network
From Psych Congress Network
Elderly Patient With Doctor
News
09/03/2024
Patients with MS had about half the rate of amyloid pathology compared with matched control subjects in the Washington University School of Medicine study.
Patients with MS had about half the rate of amyloid pathology compared with matched control subjects in the Washington University School of Medicine study.
Patients with MS had about half...
09/03/2024
Neurology
an older adult lies in a hospital bed with head turned looking out of a window
News
08/29/2024
Suvorexant, a sleep-promoting orexin receptor antagonist, was associated with lower rates of delirium than placebo in hospitalized older adults at high risk of delirium, but the difference was not statistically significant.
Suvorexant, a sleep-promoting orexin receptor antagonist, was associated with lower rates of delirium than placebo in hospitalized older adults at high risk of delirium, but the difference was not statistically significant.
Suvorexant, a sleep-promoting...
08/29/2024
Psych Congress Network
From Psych Congress Network
Dementia in PD May Occur Less Frequently Than Previously Thought
News
08/21/2024
Dementia occurrence in Parkinson disease (PD) may occur less frequently or take more time to develop than previous studies have shown, according to recent results from 2 ongoing prospective studies published in Neurology. 
Dementia occurrence in Parkinson disease (PD) may occur less frequently or take more time to develop than previous studies have shown, according to recent results from 2 ongoing prospective studies published in Neurology. 
Dementia occurrence in Parkinson...
08/21/2024
Neurology
Collaborative Dementia Care Tied with Improved Outcomes
News
08/14/2024
Collaborative dementia care management (CDCM) was associated with improved patient and caregiver outcomes over 3 years after the initial care period, according to results from a randomized controlled trial published in JAMA Network Open. U
Collaborative dementia care management (CDCM) was associated with improved patient and caregiver outcomes over 3 years after the initial care period, according to results from a randomized controlled trial published in JAMA Network Open. U
Collaborative dementia care...
08/14/2024
Neurology
quiz
Quiz
07/11/2024
What percentage of patients presenting with a syndrome suggestive of major or mild frontotemporal neurocognitive disorder (NCD) are found at autopsy to have Alzheimer disease pathology, according to the DSM-5-TR?
What percentage of patients presenting with a syndrome suggestive of major or mild frontotemporal neurocognitive disorder (NCD) are found at autopsy to have Alzheimer disease pathology, according to the DSM-5-TR?
What percentage of patients...
07/11/2024
Psych Congress Network
From Psych Congress Network
The US Food and Drug Administration headquarters sign.
07/02/2024
The US Food and Drug Administration has issued a highly-anticipated decision: the approval of donanemab—to be marketed as Kisunla by manufacturer Eli Lilly—for the treatment of early Alzheimer disease.
The US Food and Drug Administration has issued a highly-anticipated decision: the approval of donanemab—to be marketed as Kisunla by manufacturer Eli Lilly—for the treatment of early Alzheimer disease.
The US Food and Drug...
07/02/2024
Psych Congress Network
From Psych Congress Network
Lecanemab AD Treatment Could Have Low Eligibility
News
06/19/2024
Lecanemab, a recently FDA-approved treatment for Alzheimer disease (AD) may have a low eligibility rate (6.2%) among patients aged 70-89 years, according to recent results published in the journal Neurology. 
Lecanemab, a recently FDA-approved treatment for Alzheimer disease (AD) may have a low eligibility rate (6.2%) among patients aged 70-89 years, according to recent results published in the journal Neurology. 
Lecanemab, a recently...
06/19/2024
Neurology

Quizzes

quiz
Quiz
07/11/2024
What percentage of patients presenting with a syndrome suggestive of major or mild frontotemporal neurocognitive disorder (NCD) are found at autopsy to have Alzheimer disease pathology, according to the DSM-5-TR?
What percentage of patients presenting with a syndrome suggestive of major or mild frontotemporal neurocognitive disorder (NCD) are found at autopsy to have Alzheimer disease pathology, according to the DSM-5-TR?
What percentage of patients...
07/11/2024
Psych Congress Network
Pop quiz!
Quiz
04/23/2024
Put your neurology knowledge to the test with this quiz!
Put your neurology knowledge to the test with this quiz!
Put your neurology knowledge to...
04/23/2024
Neurology
Quiz
02/09/2024
How did pets affect cognitive decline?
How did pets affect cognitive decline?
How did pets affect cognitive...
02/09/2024
Neurology
Which factors were associated with young-onset dementia risk?
Quiz
01/23/2024
Did heart disease, psychedelic use, or social isolation elevate risk?
Did heart disease, psychedelic use, or social isolation elevate risk?
Did heart disease, psychedelic...
01/23/2024
Neurology
How many years of PPI use increased dementia risk?
Quiz
09/28/2023
Pop quiz!
Pop quiz!
Pop quiz!
09/28/2023
Neurology
By how much does Alzheimer Disease increase epilepsy risk?
Quiz
07/21/2023
Test your knowlege!
Test your knowlege!
Test your knowlege!
07/21/2023
Neurology
Did the MIND or Mediterranean diets affect Alzheimer Disease pathology?
Quiz
07/05/2023
Do you remember this study?
Do you remember this study?
Do you remember this study?
07/05/2023
Neurology
An illustrated picture shows two cartoon doctors, one holding up a magnifying glass to a cartoon brain.
Quiz
03/29/2023
Test your clinical knowledge with this neurology quiz!
Test your clinical knowledge with this neurology quiz!
Test your clinical knowledge...
03/29/2023
Neurology
An illustration of a pencil marking answers on a quiz sheet.
Expert Insights Quiz
02/17/2023
Test your clinical knowledge with this quick quiz!
Test your clinical knowledge with this quick quiz!
Test your clinical knowledge...
02/17/2023
Neurology
Four pencils with their erasers spelling out "quiz."
Quiz
09/28/2022
Take the quiz to test your clinical knowledge!
Take the quiz to test your clinical knowledge!
Take the quiz to test your...
09/28/2022
Psych Congress Network
Before what gestational age can brain death not be determined?
Quiz
01/13/2025
Test your guideline knowledge!
Test your guideline knowledge!
Test your guideline knowledge!
01/13/2025
Neurology
Pop quiz written on a blackboard with white chalk
Quiz
01/07/2025
Test your knowledge with this quiz!
Test your knowledge with this quiz!
Test your knowledge with this...
01/07/2025
Neurology
lady writing
Quiz
11/18/2024
According to the new National Association of Epilepsy Centers (NAEC) 2023 Guidelines, what is recommended for epilepsy centers regarding genetic testing protocols? Take the quiz to find out!
According to the new National Association of Epilepsy Centers (NAEC) 2023 Guidelines, what is recommended for epilepsy centers regarding genetic testing protocols? Take the quiz to find out!
According to the new National...
11/18/2024
Neurology
Quiz
11/18/2024
According to the new National Association of Epilepsy Centers (NAEC) 2023 Guidelines, what is recommended for epilepsy centers regarding genetic testing protocols? Take the quiz to find out!
According to the new National Association of Epilepsy Centers (NAEC) 2023 Guidelines, what is recommended for epilepsy centers regarding genetic testing protocols? Take the quiz to find out!
According to the new National...
11/18/2024
Neurology
Pop quiz written on a blackboard with white chalk
Quiz
09/24/2024
Test your knowledge of recent research with this quiz!
Test your knowledge of recent research with this quiz!
Test your knowledge of recent...
09/24/2024
Neurology
Pregnant heart
Clinical Refresh Quiz
09/06/2024
Are you up-to-date on the most recent recommendations for managing antiseizure medications in people with epilepsy of childbearing potential? Take this short, 2-part quiz to refresh your understanding of the evidence-based guidelines.
Are you up-to-date on the most recent recommendations for managing antiseizure medications in people with epilepsy of childbearing potential? Take this short, 2-part quiz to refresh your understanding of the evidence-based guidelines.
Are you up-to-date on the most...
09/06/2024
Neurology
Pop quiz written on a blackboard with white chalk
Quiz
08/15/2024
Take the quiz to test your knowledge!
Take the quiz to test your knowledge!
Take the quiz to test your...
08/15/2024
Neurology
people looking quizzical with question marks over their head
Expert Insights Quiz
08/06/2024
Take the quiz to test your knowledge!
Take the quiz to test your knowledge!
Take the quiz to test your...
08/06/2024
Neurology
quiz
Quiz
07/11/2024
What percentage of patients presenting with a syndrome suggestive of major or mild frontotemporal neurocognitive disorder (NCD) are found at autopsy to have Alzheimer disease pathology, according to the DSM-5-TR?
What percentage of patients presenting with a syndrome suggestive of major or mild frontotemporal neurocognitive disorder (NCD) are found at autopsy to have Alzheimer disease pathology, according to the DSM-5-TR?
What percentage of patients...
07/11/2024
Psych Congress Network
NLN Quiz
Quiz
07/03/2024
Comorbid ADHD is common in people with Tourettes syndrome (TS), with what range of prevalence? In children with tics and ADHD, what treatment does not worsen tics and reduces ADHD symptoms? Find out!
Comorbid ADHD is common in people with Tourettes syndrome (TS), with what range of prevalence? In children with tics and ADHD, what treatment does not worsen tics and reduces ADHD symptoms? Find out!
Comorbid ADHD is common in...
07/03/2024
Neurology

News

Deferiprone Accelerates Cognitive Decline in Patients With Early AD
News
01/16/2025
Deferiprone administered twice a day at 15 mg/kg may accelerate cognitive decline in patients with amyloid-confirmed early Alzheimer disease (AD), according to recent results from a randomized controlled trial published in JAMA Neurology.
Deferiprone administered twice a day at 15 mg/kg may accelerate cognitive decline in patients with amyloid-confirmed early Alzheimer disease (AD), according to recent results from a randomized controlled trial published in JAMA Neurology.
Deferiprone administered twice a...
01/16/2025
Neurology
a researcher examines MRI scans
News
01/02/2025
Type 2 diabetes and an abnormal amyloid-β concentration in cerebrospinal fluid were associated with accelerated brain atrophy and an earlier progression to mild cognitive impairment (MCI) in a cohort study.
Type 2 diabetes and an abnormal amyloid-β concentration in cerebrospinal fluid were associated with accelerated brain atrophy and an earlier progression to mild cognitive impairment (MCI) in a cohort study.
Type 2 diabetes and an abnormal...
01/02/2025
Neurology
Semaglutide May Lower Risk of Alzheimer Disease in Patients With Type 2 Diabetes
News
11/05/2024
Patients with type 2 diabetes and obesity prescribed semaglutide had a 40% to 70% lower risk of a first-time Alzheimer disease (AD) diagnosis compared with patients taking other antidiabetic medications, according to a study published in...
Patients with type 2 diabetes and obesity prescribed semaglutide had a 40% to 70% lower risk of a first-time Alzheimer disease (AD) diagnosis compared with patients taking other antidiabetic medications, according to a study published in...
Patients with type 2 diabetes...
11/05/2024
Psych Congress Network
An elderly woman sits on a couch
News
09/09/2024
Increasing depression symptoms in older adults were associated with early amyloid accumulation in regions responsible for emotional control, and may foretell later Alzheimer Disease (AD) development
Increasing depression symptoms in older adults were associated with early amyloid accumulation in regions responsible for emotional control, and may foretell later Alzheimer Disease (AD) development
Increasing depression symptoms...
09/09/2024
Psych Congress Network
Elderly Patient With Doctor
News
09/03/2024
Patients with MS had about half the rate of amyloid pathology compared with matched control subjects in the Washington University School of Medicine study.
Patients with MS had about half the rate of amyloid pathology compared with matched control subjects in the Washington University School of Medicine study.
Patients with MS had about half...
09/03/2024
Neurology
an older adult lies in a hospital bed with head turned looking out of a window
News
08/29/2024
Suvorexant, a sleep-promoting orexin receptor antagonist, was associated with lower rates of delirium than placebo in hospitalized older adults at high risk of delirium, but the difference was not statistically significant.
Suvorexant, a sleep-promoting orexin receptor antagonist, was associated with lower rates of delirium than placebo in hospitalized older adults at high risk of delirium, but the difference was not statistically significant.
Suvorexant, a sleep-promoting...
08/29/2024
Psych Congress Network
Dementia in PD May Occur Less Frequently Than Previously Thought
News
08/21/2024
Dementia occurrence in Parkinson disease (PD) may occur less frequently or take more time to develop than previous studies have shown, according to recent results from 2 ongoing prospective studies published in Neurology. 
Dementia occurrence in Parkinson disease (PD) may occur less frequently or take more time to develop than previous studies have shown, according to recent results from 2 ongoing prospective studies published in Neurology. 
Dementia occurrence in Parkinson...
08/21/2024
Neurology
Collaborative Dementia Care Tied with Improved Outcomes
News
08/14/2024
Collaborative dementia care management (CDCM) was associated with improved patient and caregiver outcomes over 3 years after the initial care period, according to results from a randomized controlled trial published in JAMA Network Open. U
Collaborative dementia care management (CDCM) was associated with improved patient and caregiver outcomes over 3 years after the initial care period, according to results from a randomized controlled trial published in JAMA Network Open. U
Collaborative dementia care...
08/14/2024
Neurology
Lecanemab AD Treatment Could Have Low Eligibility
News
06/19/2024
Lecanemab, a recently FDA-approved treatment for Alzheimer disease (AD) may have a low eligibility rate (6.2%) among patients aged 70-89 years, according to recent results published in the journal Neurology. 
Lecanemab, a recently FDA-approved treatment for Alzheimer disease (AD) may have a low eligibility rate (6.2%) among patients aged 70-89 years, according to recent results published in the journal Neurology. 
Lecanemab, a recently...
06/19/2024
Neurology
People Experiencing Homelessness at Higher Risk of Dementia
News
05/29/2024
People experiencing homelessness experience a higher burden of dementia compared to housed populations, according to recent population-based, cross-sectional, comparative analysis results published in The Lancet Public Health.
People experiencing homelessness experience a higher burden of dementia compared to housed populations, according to recent population-based, cross-sectional, comparative analysis results published in The Lancet Public Health.
People experiencing homelessness...
05/29/2024
Neurology
A child sleeps in bed on her stomach with her mouth hanging open
News
01/16/2025
Loudness of snoring, regardless of hypoxic burden and obstructive sleep apnea syndrome severity (OSAS), may contribute to hyperactivity in pediatric patients, according to an observational prospective study published in Sleep Medicine.
Loudness of snoring, regardless of hypoxic burden and obstructive sleep apnea syndrome severity (OSAS), may contribute to hyperactivity in pediatric patients, according to an observational prospective study published in Sleep Medicine.
Loudness of snoring, regardless...
01/16/2025
Psych Congress Network
Deferiprone Accelerates Cognitive Decline in Patients With Early AD
News
01/16/2025
Deferiprone administered twice a day at 15 mg/kg may accelerate cognitive decline in patients with amyloid-confirmed early Alzheimer disease (AD), according to recent results from a randomized controlled trial published in JAMA Neurology.
Deferiprone administered twice a day at 15 mg/kg may accelerate cognitive decline in patients with amyloid-confirmed early Alzheimer disease (AD), according to recent results from a randomized controlled trial published in JAMA Neurology.
Deferiprone administered twice a...
01/16/2025
Neurology
a patient with parkinson disease steadies a tremoring hand and wrist
News
01/16/2025
The beta-blocker propranolol reduces Parkinson disease (PD) tremor in both stressful and resting conditions, according to results from a placebo-controlled crossover trial published in the Annals of Neurology.
The beta-blocker propranolol reduces Parkinson disease (PD) tremor in both stressful and resting conditions, according to results from a placebo-controlled crossover trial published in the Annals of Neurology.
The beta-blocker propranolol...
01/16/2025
Neurology
A woman holds her forehead in pain with a migraine
News
01/13/2025
The migraine prevention drug atogepant may work immediately in patients with episodic and chronic migraine, according to a study published in Neurology.
The migraine prevention drug atogepant may work immediately in patients with episodic and chronic migraine, according to a study published in Neurology.
The migraine prevention drug...
01/13/2025
Neurology
Brain health
News
01/09/2025
Mood changes may precede symptom onset in sporadic Creutzfeldt-Jakob disease (sCJD) as early as 3 years, according to the findings from a retrospective case-control study published in JAMA Neurology.
Mood changes may precede symptom onset in sporadic Creutzfeldt-Jakob disease (sCJD) as early as 3 years, according to the findings from a retrospective case-control study published in JAMA Neurology.
Mood changes may precede symptom...
01/09/2025
Neurology
Performance Feedback Improves Quality of Care for Ischemic Stroke
News
01/02/2025
A performance feedback intervention reduced the time from door to groin puncture for patients with ischemic stroke, according to study results published in JAMA Neurology.
A performance feedback intervention reduced the time from door to groin puncture for patients with ischemic stroke, according to study results published in JAMA Neurology.
A performance feedback...
01/02/2025
Neurology
a researcher examines MRI scans
News
01/02/2025
Type 2 diabetes and an abnormal amyloid-β concentration in cerebrospinal fluid were associated with accelerated brain atrophy and an earlier progression to mild cognitive impairment (MCI) in a cohort study.
Type 2 diabetes and an abnormal amyloid-β concentration in cerebrospinal fluid were associated with accelerated brain atrophy and an earlier progression to mild cognitive impairment (MCI) in a cohort study.
Type 2 diabetes and an abnormal...
01/02/2025
Neurology
a person with restless leg syndrome lies in bed
News
12/18/2024
A new clinical practice guideline from the American Academy of Sleep Medicine recommends significant changes in the treatment of patients with restless leg syndrome (RLS), and updates the academy’s previous guidance from 2012.
A new clinical practice guideline from the American Academy of Sleep Medicine recommends significant changes in the treatment of patients with restless leg syndrome (RLS), and updates the academy’s previous guidance from 2012.
A new clinical practice...
12/18/2024
Neurology
β-Blockers Associated With Slower Huntington Disease Onset and Progression
News
12/17/2024
β-blocker use was associated with delayed motor onset in patients with premanifest Huntington disease (HD) and a slower rate of symptom worsening in patients with early motor-manifest HD, according to study findings published in JAMA...
β-blocker use was associated with delayed motor onset in patients with premanifest Huntington disease (HD) and a slower rate of symptom worsening in patients with early motor-manifest HD, according to study findings published in JAMA...
β-blocker use was associated...
12/17/2024
Neurology
a neurologist reviews a brain model with a patient
News
12/10/2024
Older adults with sleep-related daytime dysfunction, consisting of excessive sleepiness and lower enthusiasm, are at increased risk of developing a predementia syndrome called motoric cognitive risk syndrome, according to a study published in...
Older adults with sleep-related daytime dysfunction, consisting of excessive sleepiness and lower enthusiasm, are at increased risk of developing a predementia syndrome called motoric cognitive risk syndrome, according to a study published in...
Older adults with sleep-related...
12/10/2024
Neurology