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Alzheimer Disease Topic Center

Recent News and Updates

A doctor and patient talk
News
03/04/2025
Jolynn Tumolo
In older adults with normal cognition, depressive symptoms were not consistently associated with amyloid pathology. Meanwhile, depressive symptoms were associated with a reduced likelihood of amyloid pathology in older adults with mild...
In older adults with normal cognition, depressive symptoms were not consistently associated with amyloid pathology. Meanwhile, depressive symptoms were associated with a reduced likelihood of amyloid pathology in older adults with mild...
In older adults with normal...
03/04/2025
Psych Congress Network
From Psych Congress Network
Intensive Blood Pressure Control Lowers Cognitive Impairment Risk Years Later
News
02/05/2025
Jolynn Tumolo
Just over 3 years of intensive treatment to reduce systolic blood pressure in adults with hypertension and high cardiovascular risk resulted in a lower rate of cognitive impairment 7 years later, according to a study published in Neurology.
Just over 3 years of intensive treatment to reduce systolic blood pressure in adults with hypertension and high cardiovascular risk resulted in a lower rate of cognitive impairment 7 years later, according to a study published in Neurology.
Just over 3 years of intensive...
02/05/2025
Neurology
FDA building
News
01/28/2025
Meagan Thistle
The FDA has approved a supplemental biologics license application for lecanemab-irmb (Leqembi, Eisai Co., Ltd.; Biogen Inc.), an intravenous treatment (IV) for early Alzheimer disease (AD).
The FDA has approved a supplemental biologics license application for lecanemab-irmb (Leqembi, Eisai Co., Ltd.; Biogen Inc.), an intravenous treatment (IV) for early Alzheimer disease (AD).
The FDA has approved a...
01/28/2025
Psych Congress Network
From Psych Congress Network
Deferiprone Accelerates Cognitive Decline in Patients With Early AD
News
01/16/2025
Evi Arthur
Deferiprone administered twice a day at 15 mg/kg may accelerate cognitive decline in patients with amyloid-confirmed early Alzheimer disease (AD), according to recent results from a randomized controlled trial published in JAMA Neurology.
Deferiprone administered twice a day at 15 mg/kg may accelerate cognitive decline in patients with amyloid-confirmed early Alzheimer disease (AD), according to recent results from a randomized controlled trial published in JAMA Neurology.
Deferiprone administered twice a...
01/16/2025
Neurology
a researcher examines MRI scans
News
01/02/2025
Jolynn Tumolo
Type 2 diabetes and an abnormal amyloid-β concentration in cerebrospinal fluid were associated with accelerated brain atrophy and an earlier progression to mild cognitive impairment (MCI) in a cohort study.
Type 2 diabetes and an abnormal amyloid-β concentration in cerebrospinal fluid were associated with accelerated brain atrophy and an earlier progression to mild cognitive impairment (MCI) in a cohort study.
Type 2 diabetes and an abnormal...
01/02/2025
Neurology
Semaglutide May Lower Risk of Alzheimer Disease in Patients With Type 2 Diabetes
News
11/05/2024
Jolynn Tumolo
Patients with type 2 diabetes and obesity prescribed semaglutide had a 40% to 70% lower risk of a first-time Alzheimer disease (AD) diagnosis compared with patients taking other antidiabetic medications, according to a study published in...
Patients with type 2 diabetes and obesity prescribed semaglutide had a 40% to 70% lower risk of a first-time Alzheimer disease (AD) diagnosis compared with patients taking other antidiabetic medications, according to a study published in...
Patients with type 2 diabetes...
11/05/2024
Psych Congress Network
From Psych Congress Network
An elderly woman sits on a couch
News
09/09/2024
Brionna Mendoza
Increasing depression symptoms in older adults were associated with early amyloid accumulation in regions responsible for emotional control, and may foretell later Alzheimer Disease (AD) development
Increasing depression symptoms in older adults were associated with early amyloid accumulation in regions responsible for emotional control, and may foretell later Alzheimer Disease (AD) development
Increasing depression symptoms...
09/09/2024
Psych Congress Network
From Psych Congress Network
Elderly Patient With Doctor
News
09/03/2024
Jolynn Tumolo
Patients with MS had about half the rate of amyloid pathology compared with matched control subjects in the Washington University School of Medicine study.
Patients with MS had about half the rate of amyloid pathology compared with matched control subjects in the Washington University School of Medicine study.
Patients with MS had about half...
09/03/2024
Neurology
an older adult lies in a hospital bed with head turned looking out of a window
News
08/29/2024
Jolynn Tumolo
Suvorexant, a sleep-promoting orexin receptor antagonist, was associated with lower rates of delirium than placebo in hospitalized older adults at high risk of delirium, but the difference was not statistically significant.
Suvorexant, a sleep-promoting orexin receptor antagonist, was associated with lower rates of delirium than placebo in hospitalized older adults at high risk of delirium, but the difference was not statistically significant.
Suvorexant, a sleep-promoting...
08/29/2024
Psych Congress Network
From Psych Congress Network
Dementia in PD May Occur Less Frequently Than Previously Thought
News
08/21/2024
Evi Arthur
Dementia occurrence in Parkinson disease (PD) may occur less frequently or take more time to develop than previous studies have shown, according to recent results from 2 ongoing prospective studies published in Neurology. 
Dementia occurrence in Parkinson disease (PD) may occur less frequently or take more time to develop than previous studies have shown, according to recent results from 2 ongoing prospective studies published in Neurology. 
Dementia occurrence in Parkinson...
08/21/2024
Neurology
Collaborative Dementia Care Tied with Improved Outcomes
News
08/14/2024
Evi Arthur
Collaborative dementia care management (CDCM) was associated with improved patient and caregiver outcomes over 3 years after the initial care period, according to results from a randomized controlled trial published in JAMA Network Open. U
Collaborative dementia care management (CDCM) was associated with improved patient and caregiver outcomes over 3 years after the initial care period, according to results from a randomized controlled trial published in JAMA Network Open. U
Collaborative dementia care...
08/14/2024
Neurology

Quizzes

quiz
Quiz
07/11/2024
What percentage of patients presenting with a syndrome suggestive of major or mild frontotemporal neurocognitive disorder (NCD) are found at autopsy to have Alzheimer disease pathology, according to the DSM-5-TR?
What percentage of patients presenting with a syndrome suggestive of major or mild frontotemporal neurocognitive disorder (NCD) are found at autopsy to have Alzheimer disease pathology, according to the DSM-5-TR?
What percentage of patients...
07/11/2024
Psych Congress Network
Pop quiz!
Quiz
04/23/2024
Put your neurology knowledge to the test with this quiz!
Put your neurology knowledge to the test with this quiz!
Put your neurology knowledge to...
04/23/2024
Neurology
Quiz
02/09/2024
How did pets affect cognitive decline?
How did pets affect cognitive decline?
How did pets affect cognitive...
02/09/2024
Neurology
Which factors were associated with young-onset dementia risk?
Quiz
01/23/2024
Did heart disease, psychedelic use, or social isolation elevate risk?
Did heart disease, psychedelic use, or social isolation elevate risk?
Did heart disease, psychedelic...
01/23/2024
Neurology
How many years of PPI use increased dementia risk?
Quiz
09/28/2023
Pop quiz!
Pop quiz!
Pop quiz!
09/28/2023
Neurology
By how much does Alzheimer Disease increase epilepsy risk?
Quiz
07/21/2023
Test your knowlege!
Test your knowlege!
Test your knowlege!
07/21/2023
Neurology
Did the MIND or Mediterranean diets affect Alzheimer Disease pathology?
Quiz
07/05/2023
Do you remember this study?
Do you remember this study?
Do you remember this study?
07/05/2023
Neurology
An illustrated picture shows two cartoon doctors, one holding up a magnifying glass to a cartoon brain.
Quiz
03/29/2023
Test your clinical knowledge with this neurology quiz!
Test your clinical knowledge with this neurology quiz!
Test your clinical knowledge...
03/29/2023
Neurology
An illustration of a pencil marking answers on a quiz sheet.
Expert Insights Quiz
02/17/2023
Test your clinical knowledge with this quick quiz!
Test your clinical knowledge with this quick quiz!
Test your clinical knowledge...
02/17/2023
Neurology
Four pencils with their erasers spelling out "quiz."
Quiz
09/28/2022
Take the quiz to test your clinical knowledge!
Take the quiz to test your clinical knowledge!
Take the quiz to test your...
09/28/2022
Psych Congress Network
Take the Quiz!
Quiz
03/07/2025
Meagan Thistle
Think you know the key clinical features required to diagnose Parkinson disease? Put your knowledge of MDS criteria to the test!
Think you know the key clinical features required to diagnose Parkinson disease? Put your knowledge of MDS criteria to the test!
Think you know the key clinical...
03/07/2025
Neurology
A wrench with the word 'pain' on it holds the head of a wooden figurine in a vice grip
Quiz
01/28/2025
Test your knowledge of practice guidelines with this quiz!
Test your knowledge of practice guidelines with this quiz!
Test your knowledge of practice...
01/28/2025
Neurology
Before what gestational age can brain death not be determined?
Quiz
01/13/2025
Test your guideline knowledge!
Test your guideline knowledge!
Test your guideline knowledge!
01/13/2025
Neurology
Pop quiz written on a blackboard with white chalk
Quiz
01/07/2025
Test your knowledge with this quiz!
Test your knowledge with this quiz!
Test your knowledge with this...
01/07/2025
Neurology
lady writing
Quiz
11/18/2024
According to the new National Association of Epilepsy Centers (NAEC) 2023 Guidelines, what is recommended for epilepsy centers regarding genetic testing protocols? Take the quiz to find out!
According to the new National Association of Epilepsy Centers (NAEC) 2023 Guidelines, what is recommended for epilepsy centers regarding genetic testing protocols? Take the quiz to find out!
According to the new National...
11/18/2024
Neurology
Quiz
11/18/2024
According to the new National Association of Epilepsy Centers (NAEC) 2023 Guidelines, what is recommended for epilepsy centers regarding genetic testing protocols? Take the quiz to find out!
According to the new National Association of Epilepsy Centers (NAEC) 2023 Guidelines, what is recommended for epilepsy centers regarding genetic testing protocols? Take the quiz to find out!
According to the new National...
11/18/2024
Neurology
Pop quiz written on a blackboard with white chalk
Quiz
09/24/2024
Test your knowledge of recent research with this quiz!
Test your knowledge of recent research with this quiz!
Test your knowledge of recent...
09/24/2024
Neurology
Pregnant heart
Clinical Refresh Quiz
09/06/2024
Are you up-to-date on the most recent recommendations for managing antiseizure medications in people with epilepsy of childbearing potential? Take this short, 2-part quiz to refresh your understanding of the evidence-based guidelines.
Are you up-to-date on the most recent recommendations for managing antiseizure medications in people with epilepsy of childbearing potential? Take this short, 2-part quiz to refresh your understanding of the evidence-based guidelines.
Are you up-to-date on the most...
09/06/2024
Neurology
Pop quiz written on a blackboard with white chalk
Quiz
08/15/2024
Take the quiz to test your knowledge!
Take the quiz to test your knowledge!
Take the quiz to test your...
08/15/2024
Neurology
people looking quizzical with question marks over their head
Expert Insights Quiz
08/06/2024
Take the quiz to test your knowledge!
Take the quiz to test your knowledge!
Take the quiz to test your...
08/06/2024
Neurology

News

A doctor and patient talk
News
03/04/2025
Jolynn Tumolo
In older adults with normal cognition, depressive symptoms were not consistently associated with amyloid pathology. Meanwhile, depressive symptoms were associated with a reduced likelihood of amyloid pathology in older adults with mild...
In older adults with normal cognition, depressive symptoms were not consistently associated with amyloid pathology. Meanwhile, depressive symptoms were associated with a reduced likelihood of amyloid pathology in older adults with mild...
In older adults with normal...
03/04/2025
Psych Congress Network
Intensive Blood Pressure Control Lowers Cognitive Impairment Risk Years Later
News
02/05/2025
Jolynn Tumolo
Just over 3 years of intensive treatment to reduce systolic blood pressure in adults with hypertension and high cardiovascular risk resulted in a lower rate of cognitive impairment 7 years later, according to a study published in Neurology.
Just over 3 years of intensive treatment to reduce systolic blood pressure in adults with hypertension and high cardiovascular risk resulted in a lower rate of cognitive impairment 7 years later, according to a study published in Neurology.
Just over 3 years of intensive...
02/05/2025
Neurology
FDA building
News
01/28/2025
Meagan Thistle
The FDA has approved a supplemental biologics license application for lecanemab-irmb (Leqembi, Eisai Co., Ltd.; Biogen Inc.), an intravenous treatment (IV) for early Alzheimer disease (AD).
The FDA has approved a supplemental biologics license application for lecanemab-irmb (Leqembi, Eisai Co., Ltd.; Biogen Inc.), an intravenous treatment (IV) for early Alzheimer disease (AD).
The FDA has approved a...
01/28/2025
Psych Congress Network
Deferiprone Accelerates Cognitive Decline in Patients With Early AD
News
01/16/2025
Evi Arthur
Deferiprone administered twice a day at 15 mg/kg may accelerate cognitive decline in patients with amyloid-confirmed early Alzheimer disease (AD), according to recent results from a randomized controlled trial published in JAMA Neurology.
Deferiprone administered twice a day at 15 mg/kg may accelerate cognitive decline in patients with amyloid-confirmed early Alzheimer disease (AD), according to recent results from a randomized controlled trial published in JAMA Neurology.
Deferiprone administered twice a...
01/16/2025
Neurology
a researcher examines MRI scans
News
01/02/2025
Jolynn Tumolo
Type 2 diabetes and an abnormal amyloid-β concentration in cerebrospinal fluid were associated with accelerated brain atrophy and an earlier progression to mild cognitive impairment (MCI) in a cohort study.
Type 2 diabetes and an abnormal amyloid-β concentration in cerebrospinal fluid were associated with accelerated brain atrophy and an earlier progression to mild cognitive impairment (MCI) in a cohort study.
Type 2 diabetes and an abnormal...
01/02/2025
Neurology
Semaglutide May Lower Risk of Alzheimer Disease in Patients With Type 2 Diabetes
News
11/05/2024
Jolynn Tumolo
Patients with type 2 diabetes and obesity prescribed semaglutide had a 40% to 70% lower risk of a first-time Alzheimer disease (AD) diagnosis compared with patients taking other antidiabetic medications, according to a study published in...
Patients with type 2 diabetes and obesity prescribed semaglutide had a 40% to 70% lower risk of a first-time Alzheimer disease (AD) diagnosis compared with patients taking other antidiabetic medications, according to a study published in...
Patients with type 2 diabetes...
11/05/2024
Psych Congress Network
An elderly woman sits on a couch
News
09/09/2024
Brionna Mendoza
Increasing depression symptoms in older adults were associated with early amyloid accumulation in regions responsible for emotional control, and may foretell later Alzheimer Disease (AD) development
Increasing depression symptoms in older adults were associated with early amyloid accumulation in regions responsible for emotional control, and may foretell later Alzheimer Disease (AD) development
Increasing depression symptoms...
09/09/2024
Psych Congress Network
Elderly Patient With Doctor
News
09/03/2024
Jolynn Tumolo
Patients with MS had about half the rate of amyloid pathology compared with matched control subjects in the Washington University School of Medicine study.
Patients with MS had about half the rate of amyloid pathology compared with matched control subjects in the Washington University School of Medicine study.
Patients with MS had about half...
09/03/2024
Neurology
an older adult lies in a hospital bed with head turned looking out of a window
News
08/29/2024
Jolynn Tumolo
Suvorexant, a sleep-promoting orexin receptor antagonist, was associated with lower rates of delirium than placebo in hospitalized older adults at high risk of delirium, but the difference was not statistically significant.
Suvorexant, a sleep-promoting orexin receptor antagonist, was associated with lower rates of delirium than placebo in hospitalized older adults at high risk of delirium, but the difference was not statistically significant.
Suvorexant, a sleep-promoting...
08/29/2024
Psych Congress Network
Dementia in PD May Occur Less Frequently Than Previously Thought
News
08/21/2024
Evi Arthur
Dementia occurrence in Parkinson disease (PD) may occur less frequently or take more time to develop than previous studies have shown, according to recent results from 2 ongoing prospective studies published in Neurology. 
Dementia occurrence in Parkinson disease (PD) may occur less frequently or take more time to develop than previous studies have shown, according to recent results from 2 ongoing prospective studies published in Neurology. 
Dementia occurrence in Parkinson...
08/21/2024
Neurology
a human hand holds a Vitamin D supplement pill against a background of clouds in the sky on a sunny day
News
03/20/2025
Jolynn Tumolo
High-dose vitamin D reduced disease activity over 24 months in patients with clinically isolated syndrome typical for multiple sclerosis (MS) and early relapsing-remitting MS, according to study results published in JAMA.
High-dose vitamin D reduced disease activity over 24 months in patients with clinically isolated syndrome typical for multiple sclerosis (MS) and early relapsing-remitting MS, according to study results published in JAMA.
High-dose vitamin D reduced...
03/20/2025
Neurology
illustrated brain with brain waves against a black background
News
03/12/2025
Jolynn Tumolo
A newly developed tool uses algorithms trained on dynamic network models to identify hidden markers of epilepsy from a single routine scalp electroencephalogram (EEG), according to a study published in the Annals of Neurology.
A newly developed tool uses algorithms trained on dynamic network models to identify hidden markers of epilepsy from a single routine scalp electroencephalogram (EEG), according to a study published in the Annals of Neurology.
A newly developed tool uses...
03/12/2025
Neurology
fda building sign
News
03/04/2025
Brionna Mendoza
The US Food and Drug Administration (FDA) has approved tenecteplase (TNKase®), a thrombolytic agent developed by Genentech, for the treatment of acute ischemic stroke (AIS) in adults.
The US Food and Drug Administration (FDA) has approved tenecteplase (TNKase®), a thrombolytic agent developed by Genentech, for the treatment of acute ischemic stroke (AIS) in adults.
The US Food and Drug...
03/04/2025
Neurology
A doctor and patient talk
News
03/04/2025
Jolynn Tumolo
In older adults with normal cognition, depressive symptoms were not consistently associated with amyloid pathology. Meanwhile, depressive symptoms were associated with a reduced likelihood of amyloid pathology in older adults with mild...
In older adults with normal cognition, depressive symptoms were not consistently associated with amyloid pathology. Meanwhile, depressive symptoms were associated with a reduced likelihood of amyloid pathology in older adults with mild...
In older adults with normal...
03/04/2025
Psych Congress Network
A woman lies on the couch holding an ice pack to her head
News
03/03/2025
Jolynn Tumolo
Mild traumatic brain injury (mTBI) that occurred in the context of psychological trauma was associated with poorer long-term outcomes, including greater posttraumatic stress disorder (PTSD) severity, postconcussive symptoms, and disability.
Mild traumatic brain injury (mTBI) that occurred in the context of psychological trauma was associated with poorer long-term outcomes, including greater posttraumatic stress disorder (PTSD) severity, postconcussive symptoms, and disability.
Mild traumatic brain injury...
03/03/2025
Neurology
An illustration of a brain against a blue background, with a deep brain stimulation device connected via electrodes
News
02/25/2025
Brionna Mendoza
On Monday, the United States Food and Drug Administration (FDA) approved an adaptive deep brain stimulation (aDBS) technology for people living with Parkinson disease (PD).
On Monday, the United States Food and Drug Administration (FDA) approved an adaptive deep brain stimulation (aDBS) technology for people living with Parkinson disease (PD).
On Monday, the United States...
02/25/2025
Neurology
A brain puzzle against an orange background
News
02/20/2025
Jolynn Tumolo
Researchers have developed a model that achieved 93% accuracy in predicting neurologic functional independence after carotid revascularization in patients with acute stroke.
Researchers have developed a model that achieved 93% accuracy in predicting neurologic functional independence after carotid revascularization in patients with acute stroke.
Researchers have developed a...
02/20/2025
Neurology
Newer Migraine Drugs Offer No Clinically Important Advantage, ACP Guideline Reports
News
02/14/2025
Jolynn Tumolo
A new clinical guideline from the American College of Physicians (ACP) advises monotherapy for episodic migraine prevention in nonpregnant adults in the outpatient setting. The guideline, published in the Annals of Internal Medicine, provides...
A new clinical guideline from the American College of Physicians (ACP) advises monotherapy for episodic migraine prevention in nonpregnant adults in the outpatient setting. The guideline, published in the Annals of Internal Medicine, provides...
A new clinical guideline from...
02/14/2025
Neurology
A new mom sits on the couch holding her infant, and her forehead
News
02/13/2025
Brionna Mendoza
A recent Swedish cohort study of primiparous women found that those who experienced gestational hypertension, preeclampsia, and eclampsia were at increased risk for new-onset neurological disorders months or years after giving birth.
A recent Swedish cohort study of primiparous women found that those who experienced gestational hypertension, preeclampsia, and eclampsia were at increased risk for new-onset neurological disorders months or years after giving birth.
A recent Swedish cohort study of...
02/13/2025
Neurology
A person holds a cannabis joint in their hands
News
02/11/2025
Jolynn Tumolo
A lifetime history of heavy cannabis use in young adults was associated with lower brain activation during a working memory task, according to a study in JAMA Network Open
A lifetime history of heavy cannabis use in young adults was associated with lower brain activation during a working memory task, according to a study in JAMA Network Open
A lifetime history of heavy...
02/11/2025
Neurology