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Spinal Disorders Resource Center

Gene therapy
News
10/28/2024
Elivaldogene autotemcel (eli-cel) gene therapy for cerebral adrenoleukodystrophy (CALD) helped patients maintain neurological function, but also my have caused hematologic malignancies in some patients.
Elivaldogene autotemcel (eli-cel) gene therapy for cerebral adrenoleukodystrophy (CALD) helped patients maintain neurological function, but also my have caused hematologic malignancies in some patients.
Elivaldogene autotemcel...
10/28/2024
Neurology
Investigational Drug Improves Motor Function in Patients With SMA
News
10/16/2024
Apitegromab, an investigational muscle-targeted therapy, improved motor function in patients with spinal muscular atrophy (SMA), late-stage biopharmaceutical company Scholar Rock recently announced.
Apitegromab, an investigational muscle-targeted therapy, improved motor function in patients with spinal muscular atrophy (SMA), late-stage biopharmaceutical company Scholar Rock recently announced.
Apitegromab, an investigational...
10/16/2024
Neurology
News
11/15/2022
New research has called into question the “watchful waiting” strategy for infants born with spinal muscular atrophy (SMA) and multiple copies of the SMN2 gene.
New research has called into question the “watchful waiting” strategy for infants born with spinal muscular atrophy (SMA) and multiple copies of the SMN2 gene.
New research has called into...
11/15/2022
Neurology
News
03/25/2022
The US Food & Drug Administration recently approved the Evoke® Spinal Cord Stimulation (SCS) System for the treatment of chronic intractable pain of the trunk and/or limbs.
The US Food & Drug Administration recently approved the Evoke® Spinal Cord Stimulation (SCS) System for the treatment of chronic intractable pain of the trunk and/or limbs.
The US Food & Drug...
03/25/2022
Neurology
News
04/01/2021
Onasemnogene abeparvovec yielded clinically meaningful responses and a favorable benefit-risk profile for patients with spinal muscular atrophy type 1, according to findings from a recent phase 3 trial.
Onasemnogene abeparvovec yielded clinically meaningful responses and a favorable benefit-risk profile for patients with spinal muscular atrophy type 1, according to findings from a recent phase 3 trial.
Onasemnogene abeparvovec yielded...
04/01/2021
Neurology
Copper Deficiency Myeloneuropathy
Case Report and Brief Review
07/07/2020
Copper deficiency myeloneuropathy has been well studied in animal species, but the relationship with neurologic disease in humans has been identified only recently. Neurologic findings of copper deficiency are often underrecognized and...
Copper deficiency myeloneuropathy has been well studied in animal species, but the relationship with neurologic disease in humans has been identified only recently. Neurologic findings of copper deficiency are often underrecognized and...
Copper deficiency...
07/07/2020
Neurology
10/29/2019
​A 33-year-old woman with no significant past medical history presented to our family medicine practice with concern for a headache when she laughs or leans her head forward.
​A 33-year-old woman with no significant past medical history presented to our family medicine practice with concern for a headache when she laughs or leans her head forward.
​A 33-year-old woman with no...
10/29/2019
Neurology
12/28/2018
A 74-year-old man presented to his primary care provider with a 1-month history of new-onset low back pain.
A 74-year-old man presented to his primary care provider with a 1-month history of new-onset low back pain.
A 74-year-old man presented to...
12/28/2018
Neurology
News
01/10/2018
The USPSTF first released a screening recommendation for adolescent idiopathic scoliosis in 2004. Recently, the USPSTF evaluated existing evidence on the benefits and harms of screening for the condition in order to update their previous...
The USPSTF first released a screening recommendation for adolescent idiopathic scoliosis in 2004. Recently, the USPSTF evaluated existing evidence on the benefits and harms of screening for the condition in order to update their previous...
The USPSTF first released a...
01/10/2018
Neurology
01/09/2018
Scoliosis, characterized by rotation of the vertebrae by 10° or more, affects 1% to 3% of children between age 10 and 16 years.
Scoliosis, characterized by rotation of the vertebrae by 10° or more, affects 1% to 3% of children between age 10 and 16 years.
Scoliosis, characterized by...
01/09/2018
Neurology