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Multiple Sclerosis Topic Center

News
BTK Inhibitors Show Promise in MS, but Questions Remain
03/27/2023
Clinical trials of Bruton tyrosine kinase inhibitors in patients with multiple sclerosis are yielding encouraging results, but more research is needed to determine their long-term effects and place within the therapeutic landscape.
Clinical trials of Bruton tyrosine kinase inhibitors in patients with multiple sclerosis are yielding encouraging results, but more research is needed to determine their long-term effects and place within the therapeutic landscape.
Clinical trials of Bruton...
03/27/2023
Veterans Health Today
"pop quiz" written in chalk on a blackboard.
Quiz
Does stem cell therapy improve multiple sclerosis?
03/22/2023
Test your clinical knowledge with a quick quiz!
Test your clinical knowledge with a quick quiz!
Test your clinical knowledge...
03/22/2023
Neurology
News
Meta-Analysis Gauges Physical Activity in MS Patients
03/13/2023
People with multiple sclerosis (MS) averaged 21 fewer minutes of moderate-to-vigorous physical activity and 25 fewer minutes of light physical activity per day compared with healthy controls.
People with multiple sclerosis (MS) averaged 21 fewer minutes of moderate-to-vigorous physical activity and 25 fewer minutes of light physical activity per day compared with healthy controls.
People with multiple sclerosis...
03/13/2023
Neurology
News
Biosimilar Matches Reference Natalizumab for Efficacy, Safety in Relapsing-Remitting MS
02/28/2023
The proposed biosimilar natalizumab matches reference natalizumab for efficacy, safety, and immunogenicity in patients with relapsing-remitting MS.
The proposed biosimilar natalizumab matches reference natalizumab for efficacy, safety, and immunogenicity in patients with relapsing-remitting MS.
The proposed biosimilar...
02/28/2023
Neurology
News
Masitinib Appears Promising for Slowing Disability Worsening in Progressive MS
12/19/2022
Masitinib 4.5 mg/kg/d eased disability progression in patients with MS, according to a phase 3, randomized clinical trial published in Neurology: Neuroimmunology & Neuroinflammation.
Masitinib 4.5 mg/kg/d eased disability progression in patients with MS, according to a phase 3, randomized clinical trial published in Neurology: Neuroimmunology & Neuroinflammation.
Masitinib 4.5 mg/kg/d eased...
12/19/2022
Neurology
News
Novel Method Measures Whole-Brain Propagation Delays in Patients with MS
11/29/2022
A new approach described in the Journal of Neuroscience calculates functional delays across the whole brain of patients with multiple sclerosis (MS), providing a more precise measure of myelinic damage that can help guide treatment.
A new approach described in the Journal of Neuroscience calculates functional delays across the whole brain of patients with multiple sclerosis (MS), providing a more precise measure of myelinic damage that can help guide treatment.
A new approach described in the...
11/29/2022
Neurology
News
Study Tracks Immune Cell Regeneration After Stem Cell Therapy for MS
11/21/2022
Memory T cells reappear immediately after blood stem cell transplantation in patients with multiple sclerosis (MS), according to a study published in Science Translational Medicine.
Memory T cells reappear immediately after blood stem cell transplantation in patients with multiple sclerosis (MS), according to a study published in Science Translational Medicine.
Memory T cells reappear...
11/21/2022
Neurology
News
Ocrelizumab Concentration May Aid in SARS-CoV-2 Vaccine Timing for Patients With MS
11/08/2022
Serum ocrelizumab concentration measured at the time of vaccination predicted humoral response after SARS-CoV-2 vaccination in patients with multiple sclerosis (MS), with an accuracy comparable to B-cell count.
Serum ocrelizumab concentration measured at the time of vaccination predicted humoral response after SARS-CoV-2 vaccination in patients with multiple sclerosis (MS), with an accuracy comparable to B-cell count.
Serum ocrelizumab concentration...
11/08/2022
Neurology
News
Disease-Modifying Treatments for Primary Progressive MS May Lower Risk of Wheelchair Dependence
09/12/2022
Disease-modifying treatments in patients with primary progressive multiple sclerosis (MS) and persistent inflammatory activity may lower the risk of becoming wheelchair dependent, according to study findings published online in JAMA Neurology.
Disease-modifying treatments in patients with primary progressive multiple sclerosis (MS) and persistent inflammatory activity may lower the risk of becoming wheelchair dependent, according to study findings published online in JAMA Neurology.
Disease-modifying treatments in...
09/12/2022
Neurology
An array of foods that adhere to the keto diet.
Quiz
How does following a keto diet affect depression and fatigue in MS patients?
07/22/2022
Take the quiz now to test your knowledge!
Take the quiz now to test your knowledge!
Take the quiz now to test your...
07/22/2022
Neurology

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Alone or Together, CBT and Modafinil Improve MS-Related Fatigue
News
Alone or Together, CBT and Modafinil Improve MS-Related Fatigue
11/01/2024
The wake-promoting drug modafinil, CBT, and a combination of both were associated with comparable, significant improvement in fatigue at 12 weeks in patients with MS and problematic fatigue.
The wake-promoting drug modafinil, CBT, and a combination of both were associated with comparable, significant improvement in fatigue at 12 weeks in patients with MS and problematic fatigue.
The wake-promoting drug...
11/01/2024
Neurology
Tolebrutinib Delays Disability Progression in Nonrelapsing Secondary Progressive MS
News
Tolebrutinib Delays Disability Progression in Nonrelapsing Secondary Progressive MS
10/15/2024
Tolebrutinib delayed the time to onset of 6-month confirmed disability progression compared with placebo in patients with nonrelapsing secondary progressive MS, according to results presented at the European Committee for Treatment and...
Tolebrutinib delayed the time to onset of 6-month confirmed disability progression compared with placebo in patients with nonrelapsing secondary progressive MS, according to results presented at the European Committee for Treatment and...
Tolebrutinib delayed the time to...
10/15/2024
Neurology
Anti-CD20 Therapies Do Not Slow Disability Worsening in Primary Progressive MS
News
Anti-CD20 Therapies Do Not Slow Disability Worsening in Primary Progressive MS
10/07/2024
Disability progression was no slower in patients with primary progressive multiple sclerosis (MS) treated with anti-CD20 infusion therapies than in untreated patients, according to a study of real-world patients published in Neurology.
Disability progression was no slower in patients with primary progressive multiple sclerosis (MS) treated with anti-CD20 infusion therapies than in untreated patients, according to a study of real-world patients published in Neurology.
Disability progression was no...
10/07/2024
Neurology
A woman sits on the couch with her arms wrapped around her legs, looking unhappy
News
Comorbidity Burden May Increase Disease Activity in MS Patients
09/30/2024
A higher comorbidity burden in clinical trial participants with multiple sclerosis (MS) was associated with an increased hazard of MS disease activity, according to study results published  in JAMA Neurology.
A higher comorbidity burden in clinical trial participants with multiple sclerosis (MS) was associated with an increased hazard of MS disease activity, according to study results published  in JAMA Neurology.
A higher comorbidity burden in...
09/30/2024
Neurology
a patient sits in a wheelchair
News
Phase 3 Studies Find Mixed Results for Investigational MS Drug
09/18/2024
An investigational drug for patients with multiple sclerosis (MS) yielded mixed results in a trio of phase 3 trials.
An investigational drug for patients with multiple sclerosis (MS) yielded mixed results in a trio of phase 3 trials.
An investigational drug for...
09/18/2024
Neurology
Elderly Patient With Doctor
News
Patients with Multiple Sclerosis Less Likely to Develop Alzheimer Disease
09/03/2024
Patients with MS had about half the rate of amyloid pathology compared with matched control subjects in the Washington University School of Medicine study.
Patients with MS had about half the rate of amyloid pathology compared with matched control subjects in the Washington University School of Medicine study.
Patients with MS had about half...
09/03/2024
Neurology
A person walks down a boarded path with sunlight and trees in the background
News
Backward Walking Speed Reserve Reflects Disease Severity in Patients With MS
07/30/2024
Backward walking speed reserve, or the difference between an individual’s preferred and maximal backward walking speed, was associated with disease severity in patients with multiple sclerosis (MS).
Backward walking speed reserve, or the difference between an individual’s preferred and maximal backward walking speed, was associated with disease severity in patients with multiple sclerosis (MS).
Backward walking speed reserve,...
07/30/2024
Neurology
A teddy bear against a blue background wearing a mask and stethoscope.
News
Children Exposed to MS Drugs Through Breastfeeding Show No Developmental Harm
03/26/2024
Monoclonal antibodies taken for multiple sclerosis (MS) while breastfeeding appears not to affect a child’s development during the first 3 years of life, according to results from a preliminary study.
Monoclonal antibodies taken for multiple sclerosis (MS) while breastfeeding appears not to affect a child’s development during the first 3 years of life, according to results from a preliminary study.
Monoclonal antibodies taken for...
03/26/2024
Neurology
FDA headquarters
News
FDA Declines to Approve Application for Long-Acting Injection Targeting MS
03/13/2024
The US FDA has declined to approve glatiramer acetate depot 40mg (GA Depot 40), a long-acting investigational formulation of glatiramer acetate for the treatment of relapse-remitting multiple sclerosis (RRMS).
The US FDA has declined to approve glatiramer acetate depot 40mg (GA Depot 40), a long-acting investigational formulation of glatiramer acetate for the treatment of relapse-remitting multiple sclerosis (RRMS).
The US FDA has declined to...
03/13/2024
Neurology
News
In MS, Patients With Central Neuropathic Pain Carry Highest Emotional Burden
12/11/2023
Emotional burden and pain severity were greater in patients with multiple sclerosis (MS) who had central neuropathic pain than those who had musculoskeletal pain.
Emotional burden and pain severity were greater in patients with multiple sclerosis (MS) who had central neuropathic pain than those who had musculoskeletal pain.
Emotional burden and pain...
12/11/2023
Neurology
Semaglutide May Lower Risk of Alzheimer Disease in Patients With Type 2 Diabetes
News
Semaglutide May Lower Risk of Alzheimer Disease in Patients With Type 2 Diabetes
11/05/2024
Patients with type 2 diabetes and obesity prescribed semaglutide had a 40% to 70% lower risk of a first-time Alzheimer disease (AD) diagnosis compared with patients taking other antidiabetic medications, according to a study published in...
Patients with type 2 diabetes and obesity prescribed semaglutide had a 40% to 70% lower risk of a first-time Alzheimer disease (AD) diagnosis compared with patients taking other antidiabetic medications, according to a study published in...
Patients with type 2 diabetes...
11/05/2024
Psych Congress Network
Alone or Together, CBT and Modafinil Improve MS-Related Fatigue
News
Alone or Together, CBT and Modafinil Improve MS-Related Fatigue
11/01/2024
The wake-promoting drug modafinil, CBT, and a combination of both were associated with comparable, significant improvement in fatigue at 12 weeks in patients with MS and problematic fatigue.
The wake-promoting drug modafinil, CBT, and a combination of both were associated with comparable, significant improvement in fatigue at 12 weeks in patients with MS and problematic fatigue.
The wake-promoting drug...
11/01/2024
Neurology
Gene therapy
News
Concerns Linger After Gene Therapy Shows Long-Term Benefit for Cerebral Adrenoleukodystrophy
10/28/2024
Elivaldogene autotemcel (eli-cel) gene therapy for cerebral adrenoleukodystrophy (CALD) helped patients maintain neurological function, but also my have caused hematologic malignancies in some patients.
Elivaldogene autotemcel (eli-cel) gene therapy for cerebral adrenoleukodystrophy (CALD) helped patients maintain neurological function, but also my have caused hematologic malignancies in some patients.
Elivaldogene autotemcel...
10/28/2024
Neurology
Patient with family
News
During Recovery, Stroke Patients Benefit from Supportive Social Networks
10/24/2024
Large networks of family and friends are beneficial for blood pressure improvement among patients who experienced a stroke, according to a study published online in the International Journal of Cerebrovascular Disease and Stroke. “In aging...
Large networks of family and friends are beneficial for blood pressure improvement among patients who experienced a stroke, according to a study published online in the International Journal of Cerebrovascular Disease and Stroke. “In aging...
Large networks of family and...
10/24/2024
Neurology
International Stroke Burden Saw Hike Over Last 30 Years
News
International Stroke Burden Saw Hike Over Last 30 Years
10/22/2024
International stroke burden has increased from 1990 to 2021, according to recent findings from a global burden of disease (GBD) study published in The Lancet Neurology.
International stroke burden has increased from 1990 to 2021, according to recent findings from a global burden of disease (GBD) study published in The Lancet Neurology.
International stroke burden has...
10/22/2024
Neurology
Hands holding a head in profile with an illustrated heart over brain
News
Antiseizure Meds May Increase Cardiovascular Risk in Older Adults With Epilepsy
10/21/2024
A lifetime history of epilepsy is associated with new-onset cardiovascular events in older adults, according to study results published in JAMA Neurology.
A lifetime history of epilepsy is associated with new-onset cardiovascular events in older adults, according to study results published in JAMA Neurology.
A lifetime history of epilepsy...
10/21/2024
Neurology
FDA approval stamp
News
FDA Approves Infusion Treatment for Advanced Parkinson Disease in Adults
10/18/2024
AbbVie’s VYALEV (foscarbidopa and foslevodopa), the first 24-hour continuous subcutaneous infusion of levodopa-based therapy for managing motor fluctuations in adults with advanced Parkinson disease (PD), approved by the FDA.
AbbVie’s VYALEV (foscarbidopa and foslevodopa), the first 24-hour continuous subcutaneous infusion of levodopa-based therapy for managing motor fluctuations in adults with advanced Parkinson disease (PD), approved by the FDA.
AbbVie’s VYALEV (foscarbidopa...
10/18/2024
Neurology
Investigational Drug Improves Motor Function in Patients With SMA
News
Investigational Drug Improves Motor Function in Patients With SMA
10/16/2024
Apitegromab, an investigational muscle-targeted therapy, improved motor function in patients with spinal muscular atrophy (SMA), late-stage biopharmaceutical company Scholar Rock recently announced.
Apitegromab, an investigational muscle-targeted therapy, improved motor function in patients with spinal muscular atrophy (SMA), late-stage biopharmaceutical company Scholar Rock recently announced.
Apitegromab, an investigational...
10/16/2024
Neurology
Tolebrutinib Delays Disability Progression in Nonrelapsing Secondary Progressive MS
News
Tolebrutinib Delays Disability Progression in Nonrelapsing Secondary Progressive MS
10/15/2024
Tolebrutinib delayed the time to onset of 6-month confirmed disability progression compared with placebo in patients with nonrelapsing secondary progressive MS, according to results presented at the European Committee for Treatment and...
Tolebrutinib delayed the time to onset of 6-month confirmed disability progression compared with placebo in patients with nonrelapsing secondary progressive MS, according to results presented at the European Committee for Treatment and...
Tolebrutinib delayed the time to...
10/15/2024
Neurology
An orange prescription container with generic pills spilling out in front of it
News
Masked Taper Plus CBT for Insomnia Effective in Benzodiazepine Discontinuation
10/10/2024
A masked drug taper combined with cognitive behavioral therapy for insomnia (CBTI) were associated with improved benzodiazepine receptor agonist discontinuation in patients receiving treatment for insomnia
A masked drug taper combined with cognitive behavioral therapy for insomnia (CBTI) were associated with improved benzodiazepine receptor agonist discontinuation in patients receiving treatment for insomnia
A masked drug taper combined...
10/10/2024
Psych Congress Network

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Alzheimer's Disease CME Series

Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient Resources
11/19/2020
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient Resources To view accreditation information/faculty disclosures for the program, click 
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient Resources To view accreditation information/faculty disclosures for the program, click 
Early Alzheimer’s Disease:...
11/19/2020
Neurology
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient Resources
11/19/2020
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient ResourcesOnline Form - PBHLN-NLN Alzheimers Video Series
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient ResourcesOnline Form - PBHLN-NLN Alzheimers Video Series
Early Alzheimer’s Disease:...
11/19/2020
Neurology
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient Resources
11/19/2020
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient ResourcesTo claim credit for the program, click HERE for the evaluation. You will need to log in or create an account with NACCME, and then click...
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient ResourcesTo claim credit for the program, click HERE for the evaluation. You will need to log in or create an account with NACCME, and then click...
Early Alzheimer’s Disease:...
11/19/2020
Neurology
Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data
11/17/2020
Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early...
11/17/2020
Neurology
Emerging Treatments for Early Alzheimer’s Disease: Efficacy and Safety Data
11/17/2020
Emerging Treatments for Early Alzheimer’s Disease: Efficacy and Safety Data Online Form - PBHLN-NLN Alzheimers Video Series
Emerging Treatments for Early Alzheimer’s Disease: Efficacy and Safety Data Online Form - PBHLN-NLN Alzheimers Video Series
Emerging Treatments for Early...
11/17/2020
Neurology
Emerging Treatments for Early Alzheimer’s Disease: Efficacy and Safety Data
11/17/2020
Emerging Treatments for Early Alzheimer’s Disease: Efficacy and Safety DataTo claim credit for the program, click HERE for the evaluation. You will need to log in or create an account with NACCME, and then click on the evaluation...
Emerging Treatments for Early Alzheimer’s Disease: Efficacy and Safety DataTo claim credit for the program, click HERE for the evaluation. You will need to log in or create an account with NACCME, and then click on the evaluation...
Emerging Treatments for Early...
11/17/2020
Neurology
Emerging Treatments for Early Alzheimer’s Disease: Mechanisms of Action
11/12/2020
Emerging Treatments for Early Alzheimer’s Disease: Mechanisms of Action To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early Alzheimer’s Disease: Mechanisms of Action To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early...
11/12/2020
Neurology
Early Alzheimer’s Disease Overview: Burden of Disease, Quality-of-Life Impacts, and Pathophysiology
11/12/2020
Early Alzheimer’s Disease Overview: Burden of Disease, Quality-of-Life Impacts, and Pathophysiology Online Form - PBHLN-NLN Alzheimers Video Series
Early Alzheimer’s Disease Overview: Burden of Disease, Quality-of-Life Impacts, and Pathophysiology Online Form - PBHLN-NLN Alzheimers Video Series
Early Alzheimer’s Disease...
11/12/2020
Neurology
Claim-Emerging Treatments for Early Alzheimer’s Disease: Mechanisms of Action
11/12/2020
Emerging Treatments for Early Alzheimer’s Disease: Mechanisms of ActionTo claim credit for the program, click HERE for the evaluation. You will need to log in or create an account with NACCME, and then click on the evaluation button...
Emerging Treatments for Early Alzheimer’s Disease: Mechanisms of ActionTo claim credit for the program, click HERE for the evaluation. You will need to log in or create an account with NACCME, and then click on the evaluation button...
Emerging Treatments for Early...
11/12/2020
Neurology
Current Treatment Limitations and Clinical Needs in Early Alzheimer’s Disease
11/10/2020
Current Treatment Limitations and Clinical Needs in Early Alzheimer’s Disease To view accreditation information/faculty disclosures for the program, click 
Current Treatment Limitations and Clinical Needs in Early Alzheimer’s Disease To view accreditation information/faculty disclosures for the program, click 
Current Treatment Limitations...
11/10/2020
Neurology

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