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Multiple Sclerosis Topic Center

News
Early Intervention With Teriflunomide May Delay Multiple Sclerosis in Some Individuals
08/23/2023
Brionna Mendoza
For individuals with radiologically isolated syndrome (RIS), early intervention with teriflunomide may prevent the time to development of multiple sclerosis (MS) by as much as 63%.
For individuals with radiologically isolated syndrome (RIS), early intervention with teriflunomide may prevent the time to development of multiple sclerosis (MS) by as much as 63%.
For individuals with...
08/23/2023
Neurology
An illustration of microbiota
News
For Multiple Sclerosis, First Confirmation That T Cell Activation in Gut Dependent on Microbiome
08/02/2023
Brionna Mendoza
For the first time, scientists have charted the activation of gut-based T cells in multiple sclerosis using two-photon imaging in a mouse model. Further, that activation appears to be microbiome-dependent.
For the first time, scientists have charted the activation of gut-based T cells in multiple sclerosis using two-photon imaging in a mouse model. Further, that activation appears to be microbiome-dependent.
For the first time, scientists...
08/02/2023
Neurology
MS Prevalence Most Common in White Individuals, Those in Northern US Latitudes
News
MS Prevalence Most Common in White Individuals, Those in Northern US Latitudes
07/20/2023
Evi Arthur
Non-Hispanic White people have the largest prevalence of multiple sclerosis of any racial group in the United States, followed by non-Hispanic Black individuals, according to a population-based cohort study published in JAMA Neurology. 
Non-Hispanic White people have the largest prevalence of multiple sclerosis of any racial group in the United States, followed by non-Hispanic Black individuals, according to a population-based cohort study published in JAMA Neurology. 
Non-Hispanic White people have...
07/20/2023
Neurology
Pop quiz written on a blackboard with white chalk
Quiz
Which is the superior disease-modifying therapy for MS?
07/10/2023
Put your neurology knowledge to the test with this quick quiz!
Put your neurology knowledge to the test with this quick quiz!
Put your neurology knowledge to...
07/10/2023
Neurology
Pregnant person getting their blood pressure checked
News
Fertility Treatment Does Not Raise MS Relapse Risk, Study Finds
07/10/2023
Evi Arthur
Patients with multiple sclerosis undergoing fertility treatments were not found to be at an elevated relapse risk following treatment, according to a study published in Neurology Neuroimmunology & Neuroinflammation.
Patients with multiple sclerosis undergoing fertility treatments were not found to be at an elevated relapse risk following treatment, according to a study published in Neurology Neuroimmunology & Neuroinflammation.
Patients with multiple sclerosis...
07/10/2023
Neurology
A woman sits on the floor with her head in her hands looking stressed out
News
Lifelong Stress Could Contribute to Worse MS Health, Outcomes
06/20/2023
Brionna Mendoza
Stressors experienced across the lifespan, including poverty, abuse, and divorce, have been linked with worse health and functional outcomes for people living with multiple sclerosis (MS).
Stressors experienced across the lifespan, including poverty, abuse, and divorce, have been linked with worse health and functional outcomes for people living with multiple sclerosis (MS).
Stressors experienced across the...
06/20/2023
Neurology
A neurologist examines brain scans from a multiple sclerosis patient.
News
Pro-Inflammatory Diet Increases MS Relapse Risk
06/06/2023
Brionna Mendoza
A pro-inflammatory diet is associated with a higher relapse risk and more inflammatory brain lesions in multiple sclerosis (MS) patients. Results from the prospective cohort study were published in the Multiple Sclerosis Journal.
A pro-inflammatory diet is associated with a higher relapse risk and more inflammatory brain lesions in multiple sclerosis (MS) patients. Results from the prospective cohort study were published in the Multiple Sclerosis Journal.
A pro-inflammatory diet is...
06/06/2023
Neurology
Up close detail shot of a man in a wheelchair in a park
News
For Relapsing-Remitting MS, Autologous Hematopoietic Stem Cell Transplant May Be Superior Disease-Modifying Therapy
05/23/2023
Brionna Mendoza
For the treatment of relapsing-remitting multiple sclerosis (MS), a new study has found the comparative clinical effectiveness of autologous hematopoietic stem cell transplant (AHSCT) superior to other DMTs.
For the treatment of relapsing-remitting multiple sclerosis (MS), a new study has found the comparative clinical effectiveness of autologous hematopoietic stem cell transplant (AHSCT) superior to other DMTs.
For the treatment of...
05/23/2023
Neurology
Question marks
Quiz
Does fertility treatment affect MS relapse risk?
05/10/2023
Test your knowledge!
Test your knowledge!
Test your knowledge!
05/10/2023
Neurology
Doctor examining a CT scan
News
Older Age Linked With Lower Risk of MS Activity After Stopping DMT
05/08/2023
Jolynn Tumolo
A patient’s age at discontinuation of first-line disease-modifying therapy (DMT) was a significant predictor of the return of inflammatory disease activity and relapse among patients with multiple sclerosis (MS), according to study results...
A patient’s age at discontinuation of first-line disease-modifying therapy (DMT) was a significant predictor of the return of inflammatory disease activity and relapse among patients with multiple sclerosis (MS), according to study results...
A patient’s age at...
05/08/2023
Neurology

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News
Backward Walking Speed Reserve Reflects Disease Severity in Patients With MS
07/30/2024
Backward walking speed reserve, or the difference between an individual’s preferred and maximal backward walking speed, was associated with disease severity in patients with multiple sclerosis (MS).
Backward walking speed reserve, or the difference between an individual’s preferred and maximal backward walking speed, was associated with disease severity in patients with multiple sclerosis (MS).
Backward walking speed reserve,...
07/30/2024
Neurology
A teddy bear against a blue background wearing a mask and stethoscope.
News
Children Exposed to MS Drugs Through Breastfeeding Show No Developmental Harm
03/26/2024
Jolynn Tumolo
Monoclonal antibodies taken for multiple sclerosis (MS) while breastfeeding appears not to affect a child’s development during the first 3 years of life, according to results from a preliminary study.
Monoclonal antibodies taken for multiple sclerosis (MS) while breastfeeding appears not to affect a child’s development during the first 3 years of life, according to results from a preliminary study.
Monoclonal antibodies taken for...
03/26/2024
Neurology
FDA headquarters
News
FDA Declines to Approve Application for Long-Acting Injection Targeting MS
03/13/2024
Brionna Mendoza
The US FDA has declined to approve glatiramer acetate depot 40mg (GA Depot 40), a long-acting investigational formulation of glatiramer acetate for the treatment of relapse-remitting multiple sclerosis (RRMS).
The US FDA has declined to approve glatiramer acetate depot 40mg (GA Depot 40), a long-acting investigational formulation of glatiramer acetate for the treatment of relapse-remitting multiple sclerosis (RRMS).
The US FDA has declined to...
03/13/2024
Neurology
News
In MS, Patients With Central Neuropathic Pain Carry Highest Emotional Burden
12/11/2023
Jolynn Tumolo
Emotional burden and pain severity were greater in patients with multiple sclerosis (MS) who had central neuropathic pain than those who had musculoskeletal pain.
Emotional burden and pain severity were greater in patients with multiple sclerosis (MS) who had central neuropathic pain than those who had musculoskeletal pain.
Emotional burden and pain...
12/11/2023
Neurology
A child sleeps with their hand tucked under their head
News
For Children With MS, More Sleep May Mean a Higher Quality of Life
11/21/2023
Brionna Mendoza
Sleep quality was associated with improved fatigue, depression, and quality of life (QOL) in patients with pediatric onset multiple sclerosis (POMS), according to findings from a cross-sectional study.
Sleep quality was associated with improved fatigue, depression, and quality of life (QOL) in patients with pediatric onset multiple sclerosis (POMS), according to findings from a cross-sectional study.
Sleep quality was associated...
11/21/2023
Neurology
An illustrated picture shows two cartoon doctors, one holding up a magnifying glass to a cartoon brain.
News
No Disease Activity in Two-Thirds of Patients With Relapsing-Remitting MS a Decade After Stem Cell Therapy
10/19/2023
Jolynn Tumolo
More than half of patients with relapsing-remitting multiple sclerosis (MS) who underwent autologous hematopoietic stem cell transplantation (aHSCT) experienced improved disability.
More than half of patients with relapsing-remitting multiple sclerosis (MS) who underwent autologous hematopoietic stem cell transplantation (aHSCT) experienced improved disability.
More than half of patients with...
10/19/2023
Neurology
A man with depressive symptoms looks out the window
News
Psychiatric Morbidity May be Early Sign of MS
10/11/2023
Jolynn Tumolo
Before the onset of multiple sclerosis (MS), patients are nearly twice as likely to experience psychiatric comorbidity, according to a study published in Neurology.
Before the onset of multiple sclerosis (MS), patients are nearly twice as likely to experience psychiatric comorbidity, according to a study published in Neurology.
Before the onset of multiple...
10/11/2023
Neurology
FDA Approves First Biosimilar for Relapsing Forms of MS
News
FDA Approves First Biosimilar for Relapsing Forms of MS
09/14/2023
Jolynn Tumolo
The US Food and Drug Administration (FDA) recently approved Tyruko (natalizumab-sztn), the first biosimilar of Tysabri (natalizumab) injection, for the treatment of adults with relapsing forms of multiple sclerosis (MS).
The US Food and Drug Administration (FDA) recently approved Tyruko (natalizumab-sztn), the first biosimilar of Tysabri (natalizumab) injection, for the treatment of adults with relapsing forms of multiple sclerosis (MS).
The US Food and Drug...
09/14/2023
Neurology
News
Early Intervention With Teriflunomide May Delay Multiple Sclerosis in Some Individuals
08/23/2023
Brionna Mendoza
For individuals with radiologically isolated syndrome (RIS), early intervention with teriflunomide may prevent the time to development of multiple sclerosis (MS) by as much as 63%.
For individuals with radiologically isolated syndrome (RIS), early intervention with teriflunomide may prevent the time to development of multiple sclerosis (MS) by as much as 63%.
For individuals with...
08/23/2023
Neurology
An illustration of microbiota
News
For Multiple Sclerosis, First Confirmation That T Cell Activation in Gut Dependent on Microbiome
08/02/2023
Brionna Mendoza
For the first time, scientists have charted the activation of gut-based T cells in multiple sclerosis using two-photon imaging in a mouse model. Further, that activation appears to be microbiome-dependent.
For the first time, scientists have charted the activation of gut-based T cells in multiple sclerosis using two-photon imaging in a mouse model. Further, that activation appears to be microbiome-dependent.
For the first time, scientists...
08/02/2023
Neurology
Fremanezumab Shows Positive Results for Pediatric Use in Phase 3 Trial
News
Fremanezumab Shows Positive Results for Pediatric Use in Phase 3 Trial
08/08/2024
In July, Teva announced positive results in a phase 3 trial of migraine medication Ajovy (fremanezumab) for children and adolescents, making it the first anti-CGRP (calcitonin gene-related peptide) monoclonal antibody to be effective in this...
In July, Teva announced positive results in a phase 3 trial of migraine medication Ajovy (fremanezumab) for children and adolescents, making it the first anti-CGRP (calcitonin gene-related peptide) monoclonal antibody to be effective in this...
In July, Teva announced positive...
08/08/2024
Neurology
brain waves
News
High-Dose Statins May Not Benefit Patients With Mild Ischemic Stroke
08/08/2024
Compared with moderate-dose therapy, high-dose statin therapy in patients with mild ischemic stroke did not decrease the risk of stroke recurrence and was associated with an increased risk of intracranial hemorrhage over 12 months.
Compared with moderate-dose therapy, high-dose statin therapy in patients with mild ischemic stroke did not decrease the risk of stroke recurrence and was associated with an increased risk of intracranial hemorrhage over 12 months.
Compared with moderate-dose...
08/08/2024
Neurology
An illustration of a healthcare provider conducting a telehealth appointment
News
Teleneurology Visits Acceptable to Patients Across Neurologic Conditions
08/05/2024
Regardless of their neurologic condition, patients rated outpatient teleneurology appointments as highly acceptable, according to a study published in the Journal of Neurology.
Regardless of their neurologic condition, patients rated outpatient teleneurology appointments as highly acceptable, according to a study published in the Journal of Neurology.
Regardless of their neurologic...
08/05/2024
Neurology
The US Food and Drug Administration headquarters sign.
News
DMD Gene Therapy Indication Expanded to Include Boys 4 and Older
08/01/2024
The US FDA approved an indication expansion for the gene therapy Elevidys (delandistrogene moxeparvovec-rokl) to include patients with Duchenne muscular dystrophy (DMD) with a confirmed mutation in the DMD gene who are nonambulatory and 4...
The US FDA approved an indication expansion for the gene therapy Elevidys (delandistrogene moxeparvovec-rokl) to include patients with Duchenne muscular dystrophy (DMD) with a confirmed mutation in the DMD gene who are nonambulatory and 4...
The US FDA approved an...
08/01/2024
Neurology
A person walks down a boarded path with sunlight and trees in the background
News
Backward Walking Speed Reserve Reflects Disease Severity in Patients With MS
07/30/2024
Backward walking speed reserve, or the difference between an individual’s preferred and maximal backward walking speed, was associated with disease severity in patients with multiple sclerosis (MS).
Backward walking speed reserve, or the difference between an individual’s preferred and maximal backward walking speed, was associated with disease severity in patients with multiple sclerosis (MS).
Backward walking speed reserve,...
07/30/2024
Neurology
FDA Approves Efgartigimod Alfa/Hyaluronidase for CIDP Treatment
News
FDA Approves Efgartigimod Alfa/Hyaluronidase for CIDP Treatment
07/29/2024
VYVGART Hytrulo (efgartigimod alfa/hyaluronidase) was recently approved by the Food and Drug Administration (FDA) for the treatment of adults with chronic inflammatory demyelinating polyneuropathy (CIDP). 
VYVGART Hytrulo (efgartigimod alfa/hyaluronidase) was recently approved by the Food and Drug Administration (FDA) for the treatment of adults with chronic inflammatory demyelinating polyneuropathy (CIDP). 
VYVGART Hytrulo (efgartigimod...
07/29/2024
Neurology
A middle-aged male running
News
Moderate Physical Activity May Mitigate ALS Risk for Male Patients
07/25/2024
Male individuals who engage in moderate physical activity and fitness may lower their risk for amyotrophic lateral sclerosis (ALS) later in life, according to study findings published in Neurology.
Male individuals who engage in moderate physical activity and fitness may lower their risk for amyotrophic lateral sclerosis (ALS) later in life, according to study findings published in Neurology.
Male individuals who engage in...
07/25/2024
Neurology
Pitolisant Receives FDA Approval for Pediatric Patients With Narcolepsy
News
Pitolisant Receives FDA Approval for Pediatric Patients With Narcolepsy
07/23/2024
The US Food and Drug Administration (FDA) recently approved Wakix (pitolisant) for the treatment of excessive daytime sleepiness in pediatric patients 6 years and older with narcolepsy, US maker Harmony Biosciences announced.
The US Food and Drug Administration (FDA) recently approved Wakix (pitolisant) for the treatment of excessive daytime sleepiness in pediatric patients 6 years and older with narcolepsy, US maker Harmony Biosciences announced.
The US Food and Drug...
07/23/2024
Neurology
Chronic Loneliness Associated With Hiked Stroke Risk in Older Adults
News
Chronic Loneliness Associated With Hiked Stroke Risk in Older Adults
07/22/2024
Chronic loneliness was associated with higher stroke risk, independent of other factors, according to recent prospective cohort study results published in eClinicalMedicine. 
Chronic loneliness was associated with higher stroke risk, independent of other factors, according to recent prospective cohort study results published in eClinicalMedicine. 
Chronic loneliness was...
07/22/2024
Neurology
a hand breaks a wooden human figurine in half
News
Atogepant Reduces Migraine Days in Patients With Pain Medication Overuse
07/18/2024
The calcitonin gene-related peptide inhibitor atogepant reduced monthly migraine and headache days, as well as days using pain medication, in patients with chronic migraine with and without acute medication overuse.
The calcitonin gene-related peptide inhibitor atogepant reduced monthly migraine and headache days, as well as days using pain medication, in patients with chronic migraine with and without acute medication overuse.
The calcitonin gene-related...
07/18/2024
Neurology

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Alzheimer's Disease CME Series

Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient Resources
11/19/2020
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient Resources To view accreditation information/faculty disclosures for the program, click 
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient Resources To view accreditation information/faculty disclosures for the program, click 
Early Alzheimer’s Disease:...
11/19/2020
Neurology
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient Resources
11/19/2020
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient ResourcesOnline Form - PBHLN-NLN Alzheimers Video Series
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient ResourcesOnline Form - PBHLN-NLN Alzheimers Video Series
Early Alzheimer’s Disease:...
11/19/2020
Neurology
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient Resources
11/19/2020
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient ResourcesTo claim credit for the program, click HERE for the evaluation. You will need to log in or create an account with NACCME, and then click...
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient ResourcesTo claim credit for the program, click HERE for the evaluation. You will need to log in or create an account with NACCME, and then click...
Early Alzheimer’s Disease:...
11/19/2020
Neurology
Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data
11/17/2020
Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early...
11/17/2020
Neurology
Emerging Treatments for Early Alzheimer’s Disease: Efficacy and Safety Data
11/17/2020
Emerging Treatments for Early Alzheimer’s Disease: Efficacy and Safety Data Online Form - PBHLN-NLN Alzheimers Video Series
Emerging Treatments for Early Alzheimer’s Disease: Efficacy and Safety Data Online Form - PBHLN-NLN Alzheimers Video Series
Emerging Treatments for Early...
11/17/2020
Neurology
Emerging Treatments for Early Alzheimer’s Disease: Efficacy and Safety Data
11/17/2020
Emerging Treatments for Early Alzheimer’s Disease: Efficacy and Safety DataTo claim credit for the program, click HERE for the evaluation. You will need to log in or create an account with NACCME, and then click on the evaluation...
Emerging Treatments for Early Alzheimer’s Disease: Efficacy and Safety DataTo claim credit for the program, click HERE for the evaluation. You will need to log in or create an account with NACCME, and then click on the evaluation...
Emerging Treatments for Early...
11/17/2020
Neurology
Emerging Treatments for Early Alzheimer’s Disease: Mechanisms of Action
11/12/2020
Emerging Treatments for Early Alzheimer’s Disease: Mechanisms of Action To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early Alzheimer’s Disease: Mechanisms of Action To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early...
11/12/2020
Neurology
Early Alzheimer’s Disease Overview: Burden of Disease, Quality-of-Life Impacts, and Pathophysiology
11/12/2020
Early Alzheimer’s Disease Overview: Burden of Disease, Quality-of-Life Impacts, and Pathophysiology Online Form - PBHLN-NLN Alzheimers Video Series
Early Alzheimer’s Disease Overview: Burden of Disease, Quality-of-Life Impacts, and Pathophysiology Online Form - PBHLN-NLN Alzheimers Video Series
Early Alzheimer’s Disease...
11/12/2020
Neurology
Claim-Emerging Treatments for Early Alzheimer’s Disease: Mechanisms of Action
11/12/2020
Emerging Treatments for Early Alzheimer’s Disease: Mechanisms of ActionTo claim credit for the program, click HERE for the evaluation. You will need to log in or create an account with NACCME, and then click on the evaluation button...
Emerging Treatments for Early Alzheimer’s Disease: Mechanisms of ActionTo claim credit for the program, click HERE for the evaluation. You will need to log in or create an account with NACCME, and then click on the evaluation button...
Emerging Treatments for Early...
11/12/2020
Neurology
Current Treatment Limitations and Clinical Needs in Early Alzheimer’s Disease
11/10/2020
Current Treatment Limitations and Clinical Needs in Early Alzheimer’s Disease To view accreditation information/faculty disclosures for the program, click 
Current Treatment Limitations and Clinical Needs in Early Alzheimer’s Disease To view accreditation information/faculty disclosures for the program, click 
Current Treatment Limitations...
11/10/2020
Neurology

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