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Migraine Topic Center

A woman holds her forehead in pain with a migraine
For Episodic Migraine, Emgality Shows Efficacy but Not Superiority
07/24/2023
Jolynn Tumolo
In a head-to-head clinical trial of Emgality (galcanezumab-gnlm) and Nurtec ODT (rimegepant), Emgality did not meet the study’s primary endpoint of statistical superiority.
In a head-to-head clinical trial of Emgality (galcanezumab-gnlm) and Nurtec ODT (rimegepant), Emgality did not meet the study’s primary endpoint of statistical superiority.
In a head-to-head clinical trial...
07/24/2023
Neurology
Young woman sitting in window holding head
News
Researchers Urge for New Menstrual Migraine Diagnostic Criteria
06/09/2023
Evi Arthur
Menstrual migraine (MM) was found to have different clinical characteristics than non-menstrual migraine (non-MM), indicating a need to revisit diagnostic criteria, according to a recent case-control study published in JAMA Network Open.
Menstrual migraine (MM) was found to have different clinical characteristics than non-menstrual migraine (non-MM), indicating a need to revisit diagnostic criteria, according to a recent case-control study published in JAMA Network Open.
Menstrual migraine (MM) was...
06/09/2023
Neurology
A middle-aged man wearing glasses sits holding his temple with migraine pain
News
As-Needed Intranasal Ketamine Relieves Refractory Migraine Pain in Some Patients
06/05/2023
Jolynn Tumolo
Nearly half of patients with refractory chronic migraine interviewed about their use of intranasal ketamine considered the treatment “very effective,” and more than two-thirds said it improved their quality of life.
Nearly half of patients with refractory chronic migraine interviewed about their use of intranasal ketamine considered the treatment “very effective,” and more than two-thirds said it improved their quality of life.
Nearly half of patients with...
06/05/2023
Neurology
Migraines, Cluster Headaches Associated With Circadian System
News
Migraines, Cluster Headaches Associated With Circadian System
05/02/2023
Evi Arthur
These systematic review and meta-analysis results reinforced the importance of the hypothalamus.
These systematic review and meta-analysis results reinforced the importance of the hypothalamus.
These systematic review and...
05/02/2023
Neurology
News
Thalamus May Be Key to Classifying Migraine From Cluster Headache
01/23/2023
Brionna Mendoza
A new study utilizing magnetic resonance imaging (MRI) to identify headache biomarkers suggests that the thalamus may play a central role in classifying migraine from cluster headache patients.
A new study utilizing magnetic resonance imaging (MRI) to identify headache biomarkers suggests that the thalamus may play a central role in classifying migraine from cluster headache patients.
A new study utilizing magnetic...
01/23/2023
Neurology
News
Significantly Higher Odds of Anxiety, Depressive Disorders in Children With Migraine
01/15/2023
Jolynn Tumolo
Children and teens with migraine are at higher risk of experiencing anxiety and depression symptoms and disorders compared with healthy controls, according to results from a systematic review and meta-analysis published in JAMA Pediatrics.
Children and teens with migraine are at higher risk of experiencing anxiety and depression symptoms and disorders compared with healthy controls, according to results from a systematic review and meta-analysis published in JAMA Pediatrics.
Children and teens with migraine...
01/15/2023
Psych Congress Network
News
In Migraine Prevention, Tolerability Higher for Erenumab Versus Topiramate
12/20/2022
Brionna Mendoza
For the treatment and prevention of migraine episodes, erenumab was found to have a higher tolerability versus topiramte among patients. The results from the HER-MES trial, funded by Novartis, were published in Cephalagia, a journal published...
For the treatment and prevention of migraine episodes, erenumab was found to have a higher tolerability versus topiramte among patients. The results from the HER-MES trial, funded by Novartis, were published in Cephalagia, a journal published...
For the treatment and prevention...
12/20/2022
Neurology
News
Genome-Wide Analysis Identifies 86 Previously Unknown Migraine Risk Loci
12/07/2022
Brionna Mendoza
A genome-wide association study (GWAS) of the 2 main migraine subtypes identified 123 risk loci, 86 of which were previously unknown. Results were published in an open-access article in Nature Genetics.
A genome-wide association study (GWAS) of the 2 main migraine subtypes identified 123 risk loci, 86 of which were previously unknown. Results were published in an open-access article in Nature Genetics.
A genome-wide association study...
12/07/2022
Neurology
News
For Women With Chronic Migraine, Worse Anxiety and Sleep
11/22/2022
Jolynn Tumolo
Anxiety, poor sleep, and pain catastrophizing are more common in women with migraine than in healthy women, according to a study published in The Journal of Headache and Pain.
Anxiety, poor sleep, and pain catastrophizing are more common in women with migraine than in healthy women, according to a study published in The Journal of Headache and Pain.
Anxiety, poor sleep, and pain...
11/22/2022
Neurology
quiz
Quiz
What percent of patients with endometriosis experience migraine?
10/21/2022
Take the quiz to test your mental health care knowledge!
Take the quiz to test your mental health care knowledge!
Take the quiz to test your...
10/21/2022
Neurology

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Fremanezumab Shows Positive Results for Pediatric Use in Phase 3 Trial
News
Fremanezumab Shows Positive Results for Pediatric Use in Phase 3 Trial
08/08/2024
In July, Teva announced positive results in a phase 3 trial of migraine medication Ajovy (fremanezumab) for children and adolescents, making it the first anti-CGRP (calcitonin gene-related peptide) monoclonal antibody to be effective in this...
In July, Teva announced positive results in a phase 3 trial of migraine medication Ajovy (fremanezumab) for children and adolescents, making it the first anti-CGRP (calcitonin gene-related peptide) monoclonal antibody to be effective in this...
In July, Teva announced positive...
08/08/2024
Neurology
a hand breaks a wooden human figurine in half
News
Atogepant Reduces Migraine Days in Patients With Pain Medication Overuse
07/18/2024
The calcitonin gene-related peptide inhibitor atogepant reduced monthly migraine and headache days, as well as days using pain medication, in patients with chronic migraine with and without acute medication overuse.
The calcitonin gene-related peptide inhibitor atogepant reduced monthly migraine and headache days, as well as days using pain medication, in patients with chronic migraine with and without acute medication overuse.
The calcitonin gene-related...
07/18/2024
Neurology
A woman suffers from a migraine
News
Patients With Episodic Migraine 6 Time More Likely to Reduce Monthly Migraine Days With Erenumab
04/17/2024
Brionna Mendoza
In episodic migraine, patients treated with erenumab were 6 times more likely to achieve 50% or greater reduction in monthly migraine days, compared to ongoing treatment with nonspecific oral migraine preventive medications (OMPMs). Results...
In episodic migraine, patients treated with erenumab were 6 times more likely to achieve 50% or greater reduction in monthly migraine days, compared to ongoing treatment with nonspecific oral migraine preventive medications (OMPMs). Results...
In episodic migraine, patients...
04/17/2024
Neurology
Different Factors Found to Predict Morning and Later-Day Migraines
News
Different Factors Could Predict Morning and Later-Day Migraines
02/20/2024
Jolynn Tumolo
Poor perceived sleep and decreased energy the day before were each associated with increased risk of having a migraine in the morning. Researchers published the study results in Neurology. 
Poor perceived sleep and decreased energy the day before were each associated with increased risk of having a migraine in the morning. Researchers published the study results in Neurology. 
Poor perceived sleep and...
02/20/2024
Neurology
Secondhand Smoke Exposure Significantly Associated With Headache, Migraines
News
Secondhand Smoke Exposure Significantly Associated With Headache, Migraines
01/25/2024
Evi Arthur
Heavy secondhand smoke (SHS) exposure could increase risk of severe headaches or migraines in people who have never smoked, according to a cross-sectional study published in the journal Headache. 
Heavy secondhand smoke (SHS) exposure could increase risk of severe headaches or migraines in people who have never smoked, according to a cross-sectional study published in the journal Headache. 
Heavy secondhand smoke (SHS)...
01/25/2024
Neurology
News
Epilepsy, Migraine Drug Recalled
01/12/2024
Jolynn Tumolo
Azurity Pharmaceuticals Inc. is recalling 2220 bottles of Eprontia oral solution. According to the January 10, 2024, US Food and Drug Administration (FDA) Enforcement Report, samples of the drug tested out of specification for an impurity...
Azurity Pharmaceuticals Inc. is recalling 2220 bottles of Eprontia oral solution. According to the January 10, 2024, US Food and Drug Administration (FDA) Enforcement Report, samples of the drug tested out of specification for an impurity...
Azurity Pharmaceuticals Inc. is...
01/12/2024
Pharmacy Learning Network
A woman holds her forehead in pain with a migraine while talking to a doctor
News
Novel Migraine Pathways Could Guide Drug Development
11/28/2023
Jolynn Tumolo
An analysis of genetic data from more than 1.3 million people has revealed new biological pathways associated with migraine that could potentially be targeted for drug development.
An analysis of genetic data from more than 1.3 million people has revealed new biological pathways associated with migraine that could potentially be targeted for drug development.
An analysis of genetic data from...
11/28/2023
Neurology
Peripheral Auditory Deficits More Likely in Patients With Migraine, Parkinson, Multiple Sclerosis
News
Peripheral Auditory Deficits More Likely in Patients With Migraine, Parkinson, Multiple Sclerosis
09/18/2023
Jolynn Tumolo
The risk of peripheral auditory deficits are higher in patients with migraine/headache disorders, Parkinson disease, and multiple sclerosis than in healthy individuals, according to a systematic review published in Frontiers in Neurology. 
The risk of peripheral auditory deficits are higher in patients with migraine/headache disorders, Parkinson disease, and multiple sclerosis than in healthy individuals, according to a systematic review published in Frontiers in Neurology. 
The risk of peripheral auditory...
09/18/2023
Neurology
Young woman sitting in window holding head
News
Researchers Urge for New Menstrual Migraine Diagnostic Criteria
06/09/2023
Evi Arthur
Menstrual migraine (MM) was found to have different clinical characteristics than non-menstrual migraine (non-MM), indicating a need to revisit diagnostic criteria, according to a recent case-control study published in JAMA Network Open.
Menstrual migraine (MM) was found to have different clinical characteristics than non-menstrual migraine (non-MM), indicating a need to revisit diagnostic criteria, according to a recent case-control study published in JAMA Network Open.
Menstrual migraine (MM) was...
06/09/2023
Neurology
A middle-aged man wearing glasses sits holding his temple with migraine pain
News
As-Needed Intranasal Ketamine Relieves Refractory Migraine Pain in Some Patients
06/05/2023
Jolynn Tumolo
Nearly half of patients with refractory chronic migraine interviewed about their use of intranasal ketamine considered the treatment “very effective,” and more than two-thirds said it improved their quality of life.
Nearly half of patients with refractory chronic migraine interviewed about their use of intranasal ketamine considered the treatment “very effective,” and more than two-thirds said it improved their quality of life.
Nearly half of patients with...
06/05/2023
Neurology
Fremanezumab Shows Positive Results for Pediatric Use in Phase 3 Trial
News
Fremanezumab Shows Positive Results for Pediatric Use in Phase 3 Trial
08/08/2024
In July, Teva announced positive results in a phase 3 trial of migraine medication Ajovy (fremanezumab) for children and adolescents, making it the first anti-CGRP (calcitonin gene-related peptide) monoclonal antibody to be effective in this...
In July, Teva announced positive results in a phase 3 trial of migraine medication Ajovy (fremanezumab) for children and adolescents, making it the first anti-CGRP (calcitonin gene-related peptide) monoclonal antibody to be effective in this...
In July, Teva announced positive...
08/08/2024
Neurology
brain waves
News
High-Dose Statins May Not Benefit Patients With Mild Ischemic Stroke
08/08/2024
Compared with moderate-dose therapy, high-dose statin therapy in patients with mild ischemic stroke did not decrease the risk of stroke recurrence and was associated with an increased risk of intracranial hemorrhage over 12 months.
Compared with moderate-dose therapy, high-dose statin therapy in patients with mild ischemic stroke did not decrease the risk of stroke recurrence and was associated with an increased risk of intracranial hemorrhage over 12 months.
Compared with moderate-dose...
08/08/2024
Neurology
An illustration of a healthcare provider conducting a telehealth appointment
News
Teleneurology Visits Acceptable to Patients Across Neurologic Conditions
08/05/2024
Regardless of their neurologic condition, patients rated outpatient teleneurology appointments as highly acceptable, according to a study published in the Journal of Neurology.
Regardless of their neurologic condition, patients rated outpatient teleneurology appointments as highly acceptable, according to a study published in the Journal of Neurology.
Regardless of their neurologic...
08/05/2024
Neurology
The US Food and Drug Administration headquarters sign.
News
DMD Gene Therapy Indication Expanded to Include Boys 4 and Older
08/01/2024
The US FDA approved an indication expansion for the gene therapy Elevidys (delandistrogene moxeparvovec-rokl) to include patients with Duchenne muscular dystrophy (DMD) with a confirmed mutation in the DMD gene who are nonambulatory and 4...
The US FDA approved an indication expansion for the gene therapy Elevidys (delandistrogene moxeparvovec-rokl) to include patients with Duchenne muscular dystrophy (DMD) with a confirmed mutation in the DMD gene who are nonambulatory and 4...
The US FDA approved an...
08/01/2024
Neurology
A person walks down a boarded path with sunlight and trees in the background
News
Backward Walking Speed Reserve Reflects Disease Severity in Patients With MS
07/30/2024
Backward walking speed reserve, or the difference between an individual’s preferred and maximal backward walking speed, was associated with disease severity in patients with multiple sclerosis (MS).
Backward walking speed reserve, or the difference between an individual’s preferred and maximal backward walking speed, was associated with disease severity in patients with multiple sclerosis (MS).
Backward walking speed reserve,...
07/30/2024
Neurology
FDA Approves Efgartigimod Alfa/Hyaluronidase for CIDP Treatment
News
FDA Approves Efgartigimod Alfa/Hyaluronidase for CIDP Treatment
07/29/2024
VYVGART Hytrulo (efgartigimod alfa/hyaluronidase) was recently approved by the Food and Drug Administration (FDA) for the treatment of adults with chronic inflammatory demyelinating polyneuropathy (CIDP). 
VYVGART Hytrulo (efgartigimod alfa/hyaluronidase) was recently approved by the Food and Drug Administration (FDA) for the treatment of adults with chronic inflammatory demyelinating polyneuropathy (CIDP). 
VYVGART Hytrulo (efgartigimod...
07/29/2024
Neurology
A middle-aged male running
News
Moderate Physical Activity May Mitigate ALS Risk for Male Patients
07/25/2024
Male individuals who engage in moderate physical activity and fitness may lower their risk for amyotrophic lateral sclerosis (ALS) later in life, according to study findings published in Neurology.
Male individuals who engage in moderate physical activity and fitness may lower their risk for amyotrophic lateral sclerosis (ALS) later in life, according to study findings published in Neurology.
Male individuals who engage in...
07/25/2024
Neurology
Pitolisant Receives FDA Approval for Pediatric Patients With Narcolepsy
News
Pitolisant Receives FDA Approval for Pediatric Patients With Narcolepsy
07/23/2024
The US Food and Drug Administration (FDA) recently approved Wakix (pitolisant) for the treatment of excessive daytime sleepiness in pediatric patients 6 years and older with narcolepsy, US maker Harmony Biosciences announced.
The US Food and Drug Administration (FDA) recently approved Wakix (pitolisant) for the treatment of excessive daytime sleepiness in pediatric patients 6 years and older with narcolepsy, US maker Harmony Biosciences announced.
The US Food and Drug...
07/23/2024
Neurology
Chronic Loneliness Associated With Hiked Stroke Risk in Older Adults
News
Chronic Loneliness Associated With Hiked Stroke Risk in Older Adults
07/22/2024
Chronic loneliness was associated with higher stroke risk, independent of other factors, according to recent prospective cohort study results published in eClinicalMedicine. 
Chronic loneliness was associated with higher stroke risk, independent of other factors, according to recent prospective cohort study results published in eClinicalMedicine. 
Chronic loneliness was...
07/22/2024
Neurology
a hand breaks a wooden human figurine in half
News
Atogepant Reduces Migraine Days in Patients With Pain Medication Overuse
07/18/2024
The calcitonin gene-related peptide inhibitor atogepant reduced monthly migraine and headache days, as well as days using pain medication, in patients with chronic migraine with and without acute medication overuse.
The calcitonin gene-related peptide inhibitor atogepant reduced monthly migraine and headache days, as well as days using pain medication, in patients with chronic migraine with and without acute medication overuse.
The calcitonin gene-related...
07/18/2024
Neurology

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Alzheimer's Disease CME Series

Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient Resources
11/19/2020
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient Resources To view accreditation information/faculty disclosures for the program, click 
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient Resources To view accreditation information/faculty disclosures for the program, click 
Early Alzheimer’s Disease:...
11/19/2020
Neurology
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient Resources
11/19/2020
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient ResourcesOnline Form - PBHLN-NLN Alzheimers Video Series
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient ResourcesOnline Form - PBHLN-NLN Alzheimers Video Series
Early Alzheimer’s Disease:...
11/19/2020
Neurology
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient Resources
11/19/2020
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient ResourcesTo claim credit for the program, click HERE for the evaluation. You will need to log in or create an account with NACCME, and then click...
Early Alzheimer’s Disease: Caregiver Connections, Shared Decision Making, and Patient ResourcesTo claim credit for the program, click HERE for the evaluation. You will need to log in or create an account with NACCME, and then click...
Early Alzheimer’s Disease:...
11/19/2020
Neurology
Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data
11/17/2020
Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early...
11/17/2020
Neurology
Emerging Treatments for Early Alzheimer’s Disease: Efficacy and Safety Data
11/17/2020
Emerging Treatments for Early Alzheimer’s Disease: Efficacy and Safety Data Online Form - PBHLN-NLN Alzheimers Video Series
Emerging Treatments for Early Alzheimer’s Disease: Efficacy and Safety Data Online Form - PBHLN-NLN Alzheimers Video Series
Emerging Treatments for Early...
11/17/2020
Neurology
Emerging Treatments for Early Alzheimer’s Disease: Efficacy and Safety Data
11/17/2020
Emerging Treatments for Early Alzheimer’s Disease: Efficacy and Safety DataTo claim credit for the program, click HERE for the evaluation. You will need to log in or create an account with NACCME, and then click on the evaluation...
Emerging Treatments for Early Alzheimer’s Disease: Efficacy and Safety DataTo claim credit for the program, click HERE for the evaluation. You will need to log in or create an account with NACCME, and then click on the evaluation...
Emerging Treatments for Early...
11/17/2020
Neurology
Emerging Treatments for Early Alzheimer’s Disease: Mechanisms of Action
11/12/2020
Emerging Treatments for Early Alzheimer’s Disease: Mechanisms of Action To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early Alzheimer’s Disease: Mechanisms of Action To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early...
11/12/2020
Neurology
Early Alzheimer’s Disease Overview: Burden of Disease, Quality-of-Life Impacts, and Pathophysiology
11/12/2020
Early Alzheimer’s Disease Overview: Burden of Disease, Quality-of-Life Impacts, and Pathophysiology Online Form - PBHLN-NLN Alzheimers Video Series
Early Alzheimer’s Disease Overview: Burden of Disease, Quality-of-Life Impacts, and Pathophysiology Online Form - PBHLN-NLN Alzheimers Video Series
Early Alzheimer’s Disease...
11/12/2020
Neurology
Claim-Emerging Treatments for Early Alzheimer’s Disease: Mechanisms of Action
11/12/2020
Emerging Treatments for Early Alzheimer’s Disease: Mechanisms of ActionTo claim credit for the program, click HERE for the evaluation. You will need to log in or create an account with NACCME, and then click on the evaluation button...
Emerging Treatments for Early Alzheimer’s Disease: Mechanisms of ActionTo claim credit for the program, click HERE for the evaluation. You will need to log in or create an account with NACCME, and then click on the evaluation button...
Emerging Treatments for Early...
11/12/2020
Neurology
Current Treatment Limitations and Clinical Needs in Early Alzheimer’s Disease
11/10/2020
Current Treatment Limitations and Clinical Needs in Early Alzheimer’s Disease To view accreditation information/faculty disclosures for the program, click 
Current Treatment Limitations and Clinical Needs in Early Alzheimer’s Disease To view accreditation information/faculty disclosures for the program, click 
Current Treatment Limitations...
11/10/2020
Neurology

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