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Comparative Effectiveness Research Resource Center

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News
Patient-Reported Quality of Life Analyses From the Phase 3 Momentum Study Compares Momelotiniob vs Danazol for the Treatment of Myelofibrosis
03/02/2023
A phase 3 study comparing danazol vs momelotinib for the treatment of myelofibrosis (MF) found that momelotinib demonstrated greater improvements in disease-related symptoms, physical function, and health-related quality of life among...
A phase 3 study comparing danazol vs momelotinib for the treatment of myelofibrosis (MF) found that momelotinib demonstrated greater improvements in disease-related symptoms, physical function, and health-related quality of life among...
A phase 3 study comparing...
03/02/2023
Journal of Clinical Pathways
Conference Coverage
Researchers Present Status of PACIFICA Trial for Treatment of Primary or Secondary Myelofibrosis and Severe Thrombocytopenia
01/31/2023
At the 64th ASH Annual Meeting, researchers provided information about the multinational, multicenter, randomized, controlled Phase III PACIFICA trial, which aims to gather data to validate the efficacy and safety of pacritinib vs the...
At the 64th ASH Annual Meeting, researchers provided information about the multinational, multicenter, randomized, controlled Phase III PACIFICA trial, which aims to gather data to validate the efficacy and safety of pacritinib vs the...
At the 64th ASH Annual Meeting,...
01/31/2023
Journal of Clinical Pathways
Conference Coverage
Cancer Care Equity and Collaboration
10/16/2022
At the 2022 Oncology Clinical Pathways Congress, Lawrence N Shulman, MD, Abramson Cancer Center University of Pennsylvania, summarized the status of cancer care in the United States and proposed how collaborative care can enhance quality of...
At the 2022 Oncology Clinical Pathways Congress, Lawrence N Shulman, MD, Abramson Cancer Center University of Pennsylvania, summarized the status of cancer care in the United States and proposed how collaborative care can enhance quality of...
At the 2022 Oncology Clinical...
10/16/2022
Journal of Clinical Pathways
News
Ensartinib vs Crizotinib for ALK-Positive NSCLC
09/16/2021
Ensartinib demonstrated superior efficacy to crizotinib for patients with advanced ALK-positive NSCLC in a study published in JAMA Oncology.
Ensartinib demonstrated superior efficacy to crizotinib for patients with advanced ALK-positive NSCLC in a study published in JAMA Oncology.
Ensartinib demonstrated superior...
09/16/2021
Journal of Clinical Pathways
News
Carboplatin Monotherapy vs Carboplatin Plus Paclitaxel for Older Women With Ovarian Cancer
05/12/2021
05/12/2021
Journal of Clinical Pathways
Quiz
Quiz: Acalabrutinib for Patients With CLL
04/19/2021
04/19/2021
Journal of Clinical Pathways
Enfortumab Vedotin vs Chemotherapy for Locally Advanced or Metastatic Urothelial Carcinoma
Videos
Enfortumab Vedotin vs Chemotherapy for Locally Advanced or Metastatic Urothelial Carcinoma
03/23/2021
03/23/2021
Journal of Clinical Pathways
Abiraterone vs Docetaxel for De Novo Prostate Cancer in Real-World and Trial Settings
Videos
Abiraterone vs Docetaxel for De Novo Prostate Cancer in Real-World and Trial Settings
03/18/2021
Daniel Geynisman, MD, discusses results from a study which compared real-world survival among men with de novo metastatic prostate cancer treated with abiraterone acetate or docetaxel and compared these outcomes to those seen in clinical...
Daniel Geynisman, MD, discusses results from a study which compared real-world survival among men with de novo metastatic prostate cancer treated with abiraterone acetate or docetaxel and compared these outcomes to those seen in clinical...
Daniel Geynisman, MD, discusses...
03/18/2021
Journal of Clinical Pathways
Definitive vs Conservative Treatments for Older Men With Prostate Cancer
Videos
Definitive vs Conservative Treatments for Older Men With Prostate Cancer
02/24/2021
02/24/2021
Journal of Clinical Pathways
Enzalutamide vs Apalutamide, Darolutamide, and Bicalutamide for Nonmetastatic CRPC
Videos
Enzalutamide vs Apalutamide, Darolutamide, and Bicalutamide for Nonmetastatic CRPC
02/23/2021
02/23/2021
Journal of Clinical Pathways
News
Sequential or Concurrent Chemoradiation vs Radiation Alone After Hysterectomy for Cervical Cancer
01/28/2021
01/28/2021
Journal of Clinical Pathways

News

News
Patient-Reported Quality of Life Analyses From the Phase 3 Momentum Study Compares Momelotiniob vs Danazol for the Treatment of Myelofibrosis
03/02/2023
A phase 3 study comparing danazol vs momelotinib for the treatment of myelofibrosis (MF) found that momelotinib demonstrated greater improvements in disease-related symptoms, physical function, and health-related quality of life among...
A phase 3 study comparing danazol vs momelotinib for the treatment of myelofibrosis (MF) found that momelotinib demonstrated greater improvements in disease-related symptoms, physical function, and health-related quality of life among...
A phase 3 study comparing...
03/02/2023
Journal of Clinical Pathways
Conference Coverage
Researchers Present Status of PACIFICA Trial for Treatment of Primary or Secondary Myelofibrosis and Severe Thrombocytopenia
01/31/2023
At the 64th ASH Annual Meeting, researchers provided information about the multinational, multicenter, randomized, controlled Phase III PACIFICA trial, which aims to gather data to validate the efficacy and safety of pacritinib vs the...
At the 64th ASH Annual Meeting, researchers provided information about the multinational, multicenter, randomized, controlled Phase III PACIFICA trial, which aims to gather data to validate the efficacy and safety of pacritinib vs the...
At the 64th ASH Annual Meeting,...
01/31/2023
Journal of Clinical Pathways
News
Ensartinib vs Crizotinib for ALK-Positive NSCLC
09/16/2021
Ensartinib demonstrated superior efficacy to crizotinib for patients with advanced ALK-positive NSCLC in a study published in JAMA Oncology.
Ensartinib demonstrated superior efficacy to crizotinib for patients with advanced ALK-positive NSCLC in a study published in JAMA Oncology.
Ensartinib demonstrated superior...
09/16/2021
Journal of Clinical Pathways
News
Carboplatin Monotherapy vs Carboplatin Plus Paclitaxel for Older Women With Ovarian Cancer
05/12/2021
05/12/2021
Journal of Clinical Pathways
News
Sequential or Concurrent Chemoradiation vs Radiation Alone After Hysterectomy for Cervical Cancer
01/28/2021
01/28/2021
Journal of Clinical Pathways
News
Comparative Effectiveness of Systemic Treatments for Metastatic Castration-Sensitive Prostate Cancer
01/27/2021
01/27/2021
Journal of Clinical Pathways
News
Targeted Gene Testing-Directed Treatment Cost-Effective for Metastatic GIST
10/06/2020
10/06/2020
Journal of Clinical Pathways
News
No Significant PFS Improvement With KRd Vs VRd in Newly Diagnosed MM
10/01/2020
10/01/2020
Journal of Clinical Pathways
News
Comparative Effectiveness of Larotrectinib Vs Entrectinib for Metastatic NSCLC
09/09/2020
09/09/2020
Journal of Clinical Pathways
News
Comparative Effectiveness of Digital Breast Tomosynthesis vs Digital Mammography in Community Practice
09/03/2020
09/03/2020
Journal of Clinical Pathways
News
Racial Disparities in Immune Checkpoint Inhibitor Treatment and Survival Among Patients With NSCLC
01/15/2025
Disparities in immune checkpoint inhibitor utilization and survival based on race and socioeconomic factors in patients with metastatic non-small cell lung cancer (NSCLC) underscore the need for improved access to care for vulnerable...
Disparities in immune checkpoint inhibitor utilization and survival based on race and socioeconomic factors in patients with metastatic non-small cell lung cancer (NSCLC) underscore the need for improved access to care for vulnerable...
Disparities in immune checkpoint...
01/15/2025
Journal of Clinical Pathways
News
Social Risks Lower Rates of Preventive Cancer Screenings
01/09/2025
A recent study published in JNCI Cancer Spectrum investigated the pathways through which social risks affect screening outcomes for breast, cervical, and colorectal cancer (CRC) in patients served in community-based clinics across the US.
A recent study published in JNCI Cancer Spectrum investigated the pathways through which social risks affect screening outcomes for breast, cervical, and colorectal cancer (CRC) in patients served in community-based clinics across the US.
A recent study published in JNCI...
01/09/2025
Journal of Clinical Pathways
News
A Deep Learning Model for Predicting Immune Checkpoint Inhibitor Efficacy in NSCLC
01/08/2025
Researchers developed and validated a deep learning model, Deep-IO, designed to predict the efficacy of immune checkpoint inhibitors (ICIs) in treating advanced non-small cell lung cancer (NSCLC), according to a study published in JAMA...
Researchers developed and validated a deep learning model, Deep-IO, designed to predict the efficacy of immune checkpoint inhibitors (ICIs) in treating advanced non-small cell lung cancer (NSCLC), according to a study published in JAMA...
Researchers developed and...
01/08/2025
Journal of Clinical Pathways
News
Neratinib Demonstrates Promising Efficacy for Patients With EGFR-Mutated Non-Small Cell Lung Cancer
01/08/2025
According to results from the phase 2 SUMMIT basket trial, neratinib demonstrated promising efficacy among patients with EGFR-mutated non-small cell lung cancer.
According to results from the phase 2 SUMMIT basket trial, neratinib demonstrated promising efficacy among patients with EGFR-mutated non-small cell lung cancer.
According to results from the...
01/08/2025
Oncology
News
Refining Risk Stratification for Myelofibrosis Using Real-World Data
12/20/2024
Despite advancements in understanding the molecular basis of myelofibrosis (MF), a rare and complex bone marrow disorder, predicting disease outcomes and tailoring treatments remains challenging. A study published in Cancers used real-world...
Despite advancements in understanding the molecular basis of myelofibrosis (MF), a rare and complex bone marrow disorder, predicting disease outcomes and tailoring treatments remains challenging. A study published in Cancers used real-world...
Despite advancements in...
12/20/2024
Journal of Clinical Pathways
News
Travel and Financial Burdens Play a Role in Cancer Care
12/19/2024
The joint stressors of travel burdens and financial hardship can affect the care patients with cancer receive.
The joint stressors of travel burdens and financial hardship can affect the care patients with cancer receive.
The joint stressors of travel...
12/19/2024
Journal of Clinical Pathways
News
An Evaluation of Endometrial Cancer Guidelines for Optimal Patient Care
12/17/2024
A review published in Cancers compares multiple guidelines on managing endometrial cancer, emphasizing the importance of consistent protocols and the role of molecular classification in optimizing treatment for postmenopausal women.
A review published in Cancers compares multiple guidelines on managing endometrial cancer, emphasizing the importance of consistent protocols and the role of molecular classification in optimizing treatment for postmenopausal women.
A review published in Cancers...
12/17/2024
Journal of Clinical Pathways
News
Cancer Predisposition Genes Found in 1 in 10 Patients With Multiple Myeloma
12/17/2024
Approximately 10% of patients with multiple myeloma may have an unknown cancer predisposition syndrome.
Approximately 10% of patients with multiple myeloma may have an unknown cancer predisposition syndrome.
Approximately 10% of patients...
12/17/2024
Journal of Clinical Pathways
News
Exploring Lipid Metabolism Pathways in Endometrial Cancer Growth and Metastasis
12/17/2024
Metabolic disorders such as obesity and dyslipidemia are closely linked to diagnosis and risk of endometrial cancer (EC). With incidence and mortality rates on the rise, a study in Cell Communication and Signaling analyzed how lipid...
Metabolic disorders such as obesity and dyslipidemia are closely linked to diagnosis and risk of endometrial cancer (EC). With incidence and mortality rates on the rise, a study in Cell Communication and Signaling analyzed how lipid...
Metabolic disorders such as...
12/17/2024
Journal of Clinical Pathways
News
Study Highlights Risks and Outcomes of Radiation Therapy in Patients With Endometrial Cancer
12/13/2024
Patients with endometrial cancer who receive adjuvant radiation therapy (RT) may face an increased risk of developing certain second primary malignancies (SPMs).
Patients with endometrial cancer who receive adjuvant radiation therapy (RT) may face an increased risk of developing certain second primary malignancies (SPMs).
Patients with endometrial cancer...
12/13/2024
Journal of Clinical Pathways

Videos

Enfortumab Vedotin vs Chemotherapy for Locally Advanced or Metastatic Urothelial Carcinoma
Videos
Enfortumab Vedotin vs Chemotherapy for Locally Advanced or Metastatic Urothelial Carcinoma
03/23/2021
03/23/2021
Journal of Clinical Pathways
Abiraterone vs Docetaxel for De Novo Prostate Cancer in Real-World and Trial Settings
Videos
Abiraterone vs Docetaxel for De Novo Prostate Cancer in Real-World and Trial Settings
03/18/2021
Daniel Geynisman, MD, discusses results from a study which compared real-world survival among men with de novo metastatic prostate cancer treated with abiraterone acetate or docetaxel and compared these outcomes to those seen in clinical...
Daniel Geynisman, MD, discusses results from a study which compared real-world survival among men with de novo metastatic prostate cancer treated with abiraterone acetate or docetaxel and compared these outcomes to those seen in clinical...
Daniel Geynisman, MD, discusses...
03/18/2021
Journal of Clinical Pathways
Definitive vs Conservative Treatments for Older Men With Prostate Cancer
Videos
Definitive vs Conservative Treatments for Older Men With Prostate Cancer
02/24/2021
02/24/2021
Journal of Clinical Pathways
Enzalutamide vs Apalutamide, Darolutamide, and Bicalutamide for Nonmetastatic CRPC
Videos
Enzalutamide vs Apalutamide, Darolutamide, and Bicalutamide for Nonmetastatic CRPC
02/23/2021
02/23/2021
Journal of Clinical Pathways
BDHC Thumbnail
Videos
Alternative Payment Models in Health Care: Successes, Failures, and What’s Next
01/09/2025
In this Breaking Down Health Care conversation, John Hennessy, MBA, and Michael Kolodziej, MD, discuss the evolution and challenges of alternative payment models, including accountable care organizations (ACOs), the Oncology Care Model (OCM),...
In this Breaking Down Health Care conversation, John Hennessy, MBA, and Michael Kolodziej, MD, discuss the evolution and challenges of alternative payment models, including accountable care organizations (ACOs), the Oncology Care Model (OCM),...
In this Breaking Down Health...
01/09/2025
Cancer Care Business Exchange
BDHC thumbnail
Videos
Precision Medicine in Oncology: From Testing to Therapy
12/05/2024
In this Breaking Down Health Care conversation, John Hennessy, MBA, and Michael Kolodziej, MD, explore the distinction between precision and personalized medicine, the challenges and nuances of next-generation sequencing (NGS) testing in...
In this Breaking Down Health Care conversation, John Hennessy, MBA, and Michael Kolodziej, MD, explore the distinction between precision and personalized medicine, the challenges and nuances of next-generation sequencing (NGS) testing in...
In this Breaking Down Health...
12/05/2024
Cancer Care Business Exchange
Matthew Davids, MD
Videos
Factors Impacting the Development and Selection of Targeted Therapies for Patients With CLL
12/04/2024
Matthew S. Davids, MD, speaks about the latest targeted therapies for treating CLL, the challenges in developing these treatments, and how they are being used in the community oncology setting.
Matthew S. Davids, MD, speaks about the latest targeted therapies for treating CLL, the challenges in developing these treatments, and how they are being used in the community oncology setting.
Matthew S. Davids, MD, speaks...
12/04/2024
Journal of Clinical Pathways
Videos
Driving Innovation in Cancer Care: The Future of Value-Based Care in Oncology
12/04/2024
In this interview, Gordon Kuntz discusses the Delphi Method, a Predictable Cost of Care Model developed by the Predictable Cost of Care Working Group that enhances oncology market access strategies by standardizing and broadening the economic...
In this interview, Gordon Kuntz discusses the Delphi Method, a Predictable Cost of Care Model developed by the Predictable Cost of Care Working Group that enhances oncology market access strategies by standardizing and broadening the economic...
In this interview, Gordon Kuntz...
12/04/2024
Journal of Clinical Pathways
Videos
Building Consensus for Predictable Cancer Care Costs: Applying the Delphi Method to Multidisciplinary Stakeholder Collaboration
12/02/2024
In this interview, Carole Tremonti, RN, MBA, discusses the critical role of clinical pathways in equitable cancer care, the application of the Delphi Method by the Predictable Cost of Care Working Group to foster multidisciplinary...
In this interview, Carole Tremonti, RN, MBA, discusses the critical role of clinical pathways in equitable cancer care, the application of the Delphi Method by the Predictable Cost of Care Working Group to foster multidisciplinary...
In this interview, Carole...
12/02/2024
Journal of Clinical Pathways
Danielle Brander, MD
Videos
Chronic Lymphocytic Leukemia Treatment Trends in Community Oncology Settings
11/26/2024
Danielle Brander, MD, highlights current trends in the community oncology setting for treating chronic lymphocytic leukemia (CLL) and how clinical pathways can assist oncologists with decision making for frontline therapy in CLL.
Danielle Brander, MD, highlights current trends in the community oncology setting for treating chronic lymphocytic leukemia (CLL) and how clinical pathways can assist oncologists with decision making for frontline therapy in CLL.
Danielle Brander, MD, highlights...
11/26/2024
Journal of Clinical Pathways
Videos
The Evolving Role of Pharmacists in Custom Pathway Implementation
11/25/2024
In this interview, Rebecca Maniago, PharmD, discusses the complexities of implementing custom clinical pathways, emphasizing the need for clear goals, robust resources, and ongoing updates, while highlighting the pivotal role of pharmacists...
In this interview, Rebecca Maniago, PharmD, discusses the complexities of implementing custom clinical pathways, emphasizing the need for clear goals, robust resources, and ongoing updates, while highlighting the pivotal role of pharmacists...
In this interview, Rebecca...
11/25/2024
Journal of Clinical Pathways
Danielle Brander, MD
Videos
Insights on BTK Inhibitors as Frontline Treatment for Chronic Lymphocytic Leukemia
11/22/2024
Danielle Brander, MD, discusses the latest National Comprehensive Cancer Network guidelines for chronic lymphocytic leukemia (CLL) and the efficacy of BTK inhibitors as monotherapy in the frontline treatment of CLL.
Danielle Brander, MD, discusses the latest National Comprehensive Cancer Network guidelines for chronic lymphocytic leukemia (CLL) and the efficacy of BTK inhibitors as monotherapy in the frontline treatment of CLL.
Danielle Brander, MD, discusses...
11/22/2024
Journal of Clinical Pathways
Chang Headshot
Videos
Optimizing Pathways in NSCLC With Immunotherapy and Radiation
11/22/2024
Joe Y. Chang, MD, PhD, explores advancements in NSCLC treatment pathways, emphasizing the integration of immunotherapy and precision radiotherapy, the role of value-based care in palliative approaches, and the potential of artificial...
Joe Y. Chang, MD, PhD, explores advancements in NSCLC treatment pathways, emphasizing the integration of immunotherapy and precision radiotherapy, the role of value-based care in palliative approaches, and the potential of artificial...
Joe Y. Chang, MD, PhD, explores...
11/22/2024
Journal of Clinical Pathways
Kolodziej Headshot
Videos
Understanding the Impact of Venture Capital and Private Equity in Oncology
11/18/2024
Michael Kolodziej, MD, discusses the growing influence of venture capital and private equity in oncology care, highlighting the potential for these trends to reshape costs, partnerships, and innovation in the oncology landscape.
Michael Kolodziej, MD, discusses the growing influence of venture capital and private equity in oncology care, highlighting the potential for these trends to reshape costs, partnerships, and innovation in the oncology landscape.
Michael Kolodziej, MD, discusses...
11/18/2024
Journal of Clinical Pathways
Nov-Dec 2024 Issue Cover

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Special Reports

JCP Special Report
Recommendations for Creating an Oncology Clinical Pathways Framework Tool Based on Payer, Provider, and Patient Priorities: Findings From the 2021 Care Pathways Working Group
05/20/2022
The Journal of Clinical Pathways convened the 2021 Care Pathways Working Group to identify and reconcile the different pathway drivers for each stakeholder now and five years into the future, creating a framework tool based on oncology care...
The Journal of Clinical Pathways convened the 2021 Care Pathways Working Group to identify and reconcile the different pathway drivers for each stakeholder now and five years into the future, creating a framework tool based on oncology care...
The Journal of Clinical Pathways...
05/20/2022
Journal of Clinical Pathways

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Journal of Clinical Pathways Newsletter

Recent Stories

News
Patient-Reported Quality of Life Analyses From the Phase 3 Momentum Study Compares Momelotiniob vs Danazol for the Treatment of Myelofibrosis
03/02/2023
A phase 3 study comparing danazol vs momelotinib for the treatment of myelofibrosis (MF) found that momelotinib demonstrated greater improvements in disease-related symptoms, physical function, and health-related quality of life among...
A phase 3 study comparing danazol vs momelotinib for the treatment of myelofibrosis (MF) found that momelotinib demonstrated greater improvements in disease-related symptoms, physical function, and health-related quality of life among...
A phase 3 study comparing...
03/02/2023
Journal of Clinical Pathways
Conference Coverage
Researchers Present Status of PACIFICA Trial for Treatment of Primary or Secondary Myelofibrosis and Severe Thrombocytopenia
01/31/2023
At the 64th ASH Annual Meeting, researchers provided information about the multinational, multicenter, randomized, controlled Phase III PACIFICA trial, which aims to gather data to validate the efficacy and safety of pacritinib vs the...
At the 64th ASH Annual Meeting, researchers provided information about the multinational, multicenter, randomized, controlled Phase III PACIFICA trial, which aims to gather data to validate the efficacy and safety of pacritinib vs the...
At the 64th ASH Annual Meeting,...
01/31/2023
Journal of Clinical Pathways
Conference Coverage
Cancer Care Equity and Collaboration
10/16/2022
At the 2022 Oncology Clinical Pathways Congress, Lawrence N Shulman, MD, Abramson Cancer Center University of Pennsylvania, summarized the status of cancer care in the United States and proposed how collaborative care can enhance quality of...
At the 2022 Oncology Clinical Pathways Congress, Lawrence N Shulman, MD, Abramson Cancer Center University of Pennsylvania, summarized the status of cancer care in the United States and proposed how collaborative care can enhance quality of...
At the 2022 Oncology Clinical...
10/16/2022
Journal of Clinical Pathways
News
Ensartinib vs Crizotinib for ALK-Positive NSCLC
09/16/2021
Ensartinib demonstrated superior efficacy to crizotinib for patients with advanced ALK-positive NSCLC in a study published in JAMA Oncology.
Ensartinib demonstrated superior efficacy to crizotinib for patients with advanced ALK-positive NSCLC in a study published in JAMA Oncology.
Ensartinib demonstrated superior...
09/16/2021
Journal of Clinical Pathways
News
Carboplatin Monotherapy vs Carboplatin Plus Paclitaxel for Older Women With Ovarian Cancer
05/12/2021
05/12/2021
Journal of Clinical Pathways

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